TABLE OF CONTENTS

Volume 16, Issue 3 (March 2009)

Special Issue on Cell death mechanisms


Although cell death occurs in many different ways, it uses several common and evolutionarily conserved mechanisms. These control distinct forms of cell demise ranging from necrosis and excitotoxicity to autophagy and apoptosis. This review series comprises state-of the art reviews, which summarise our knowledge of basic mechanisms of cell death in a context of different pathological processes. Articles, written by the leaders in the field, present a comprehensive picture of cell-death routines and their role in shaping diseases. This collection of papers should serve as a key resource to researchers in cell biology, neurobiology, oncology, biochemistry and pharmacology.

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Editorial

The cell death forum  FREE

A Verkhratsky and A Hague

Cell Death Differ 16: 359; doi:10.1038/cdd.2008.180

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Reviews

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

M Vogler, D Dinsdale, M J S Dyer and G M Cohen

Cell Death Differ 16: 360-367; advance online publication, September 19, 2008; doi:10.1038/cdd.2008.137

Tumour cell survival signalling by the ERK1/2 pathway FREE

K Balmanno and S J Cook

Cell Death Differ 16: 368-377; advance online publication, October 10, 2008; doi:10.1038/cdd.2008.148

Astroglia in dementia and Alzheimer's disease FREE

J J Rodríguez, M Olabarria, A Chvatal and A Verkhratsky

Cell Death Differ 16: 378-385; advance online publication, December 5, 2008; doi:10.1038/cdd.2008.172

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Original Papers

Abeta40 promotes neuronal cell fate in neural progenitor cells

Y Chen and C Dong

Cell Death Differ 16: 386-394; advance online publication, June 20, 2008; doi:10.1038/cdd.2008.94

Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc

C-Y Zhu, C-Y Li, Y Li, Y-Q Zhan, Y-H Li, C-W Xu, W-X Xu, H B Sun and X-M Yang

Cell Death Differ 16: 395-405; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.160

Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death

M Delgado, P Anderson, J A Garcia-Salcedo, M Caro and E Gonzalez-Rey

Cell Death Differ 16: 406-416; advance online publication, December 5, 2008; doi:10.1038/cdd.2008.161

Galectin-1 promotes basal and kainate-induced proliferation of neural progenitors in the dentate gyrus of adult mouse hippocampus

K Kajitani, H Nomaru, M Ifuku, N Yutsudo, Y Dan, T Miura, D Tsuchimoto, K Sakumi, T Kadoya, H Horie, F Poirier, M Noda and Y Nakabeppu

Cell Death Differ 16: 417-427; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.162

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations

S Zucchelli, S Vilotti, R Calligaris, Z S Lavina, M Biagioli, R Foti, L De Maso, M Pinto, M Gorza, E Speretta, C Casseler, G Tell, G Del Sal and S Gustincich

Cell Death Differ 16: 428-438; advance online publication, November 21, 2008; doi:10.1038/cdd.2008.169

Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging

T C Jackson, A Rani, A Kumar and T C Foster

Cell Death Differ 16: 439-448; advance online publication, November 28, 2008; doi:10.1038/cdd.2008.171

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

N Moisoi, K Klupsch, V Fedele, P East, S Sharma, A Renton, H Plun-Favreau, R E Edwards, P Teismann, M D Esposti, A D Morrison, N W Wood, J Downward and L M Martins

Cell Death Differ 16: 449-464; advance online publication, November 21, 2008; doi:10.1038/cdd.2008.166

Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages

S Jaillon, P Jeannin, Y Hamon, I Frémaux, A Doni, B Bottazzi, S Blanchard, J-F Subra, A Chevailler, A Mantovani and Y Delneste

Cell Death Differ 16: 465-474; advance online publication, December 12, 2008; doi:10.1038/cdd.2008.173

Polarized fluid movement and not cell death, creates luminal spaces in adult prostate epithelium

J F Pearson, S Hughes, K Chambers and S H Lang

Cell Death Differ 16: 475-482; advance online publication, December 19, 2008; doi:10.1038/cdd.2008.181

Mitotic catastrophe is the predominant response to histone acetyltransferase depletion

G-H Ha, H-S Kim, C G Lee, H-Y Park, E-J Kim, H-J Shin, J-C Lee, K-W Lee and C-W Lee

Cell Death Differ 16: 483-497; advance online publication, December 19, 2008; doi:10.1038/cdd.2008.182

Inhibition of Aurora B kinase sensitizes a subset of human glioma cells to TRAIL concomitant with induction of TRAIL-R2

J Li, M G Anderson, L A Tucker, Y Shen, K B Glaser and O J Shah

Cell Death Differ 16: 498-511; advance online publication, December 12, 2008; doi:10.1038/cdd.2008.174

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Meeting Report

Cell death mechanisms: life in the balance

A Hague and A Verkhratsky

Cell Death Differ 16: 512-514; doi:10.1038/cdd.2008.157

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