TABLE OF CONTENTS
Volume 16, Issue 1 (January 2009)
Special Issue on Autophagy in Aging, Disease and Death
Autophagy ('self-eating') is one of the most intriguing phenomena in cell biology. It is a process by which the cellular content is digested by the lysosomal machinery. Autophagy is functionally related to a diverse range of stress responses, including cell death. In this special issue of Cell Death & Differentiation, prominent scientists review the basic physiology of autophagy, as well as its implications for health and disease, in infection, immune responses, cancer, a range of organ-specific pathologies,and in age-related disorders.
See articles marked 
Editorial
Autophagy in aging, disease and death: the true identity of a cell death impostor
FREE
B Levine and G Kroemer
Cell Death Differ 16: 1-2; doi:10.1038/cdd.2008.139
Reviews
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
FREE
G Kroemer, L Galluzzi, P Vandenabeele, J Abrams, E S Alnemri, E H Baehrecke, M V Blagosklonny, W S El-Deiry, P Golstein, D R Green, M Hengartner, R A Knight, S Kumar, S A Lipton, W Malorni, G Nuñez, M E Peter, J Tschopp, J Yuan, M Piacentini, B Zhivotovsky and G Melino
Cell Death Differ 16: 3-11; advance online publication, October 10, 2008; doi:10.1038/cdd.2008.150
Does autophagy have a license to kill mammalian cells?
FREE
F Scarlatti, R Granata, A J Meijer and P Codogno
Cell Death Differ 16: 12-20; advance online publication, July 4, 2008; doi:10.1038/cdd.2008.101
Autophagy and cell death in model organisms
FREE
N Kourtis and N Tavernarakis
Cell Death Differ 16: 21-30; advance online publication, August 22, 2008; doi:10.1038/cdd.2008.120
The role of autophagy in the heart
FREE
K Nishida, S Kyoi, O Yamaguchi, J Sadoshima and K Otsu
Cell Death Differ 16: 31-38; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.163
Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in
-1-antitrypsin deficiency
FREE
D H Perlmutter
Cell Death Differ 16: 39-45; advance online publication, July 11, 2008; doi:10.1038/cdd.2008.103
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
FREE
S Sarkar, B Ravikumar, R A Floto and D C Rubinsztein
Cell Death Differ 16: 46-56; advance online publication, July 18, 2008; doi:10.1038/cdd.2008.110
Eating the enemy within: autophagy in infectious diseases
FREE
A Orvedahl and B Levine
Cell Death Differ 16: 57-69; advance online publication, September 5, 2008; doi:10.1038/cdd.2008.130
Autophagy and multivesicular bodies: two closely related partners
FREE
C M Fader and M I Colombo
Cell Death Differ 16: 70-78; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.168
Autophagy in CD4+ T-cell immunity and tolerance
FREE
J D Lünemann and C Münz
Cell Death Differ 16: 79-86; advance online publication, July 18, 2008; doi:10.1038/cdd.2008.113
Control of autophagy by oncogenes and tumor suppressor genes
FREE
M C Maiuri, E Tasdemir, A Criollo, E Morselli, J M Vicencio, R Carnuccio and G Kroemer
Cell Death Differ 16: 87-93; advance online publication, September 19, 2008; doi:10.1038/cdd.2008.131
Autophagy genes and ageing
FREE
T Vellai
Cell Death Differ 16: 94-102; advance online publication, September 12, 2008; doi:10.1038/cdd.2008.126
Original Papers
FOXA1 and IRF-1 intermediary transcriptional regulators of PPAR
-induced urothelial cytodifferentiation
C L Varley, E J Bacon, J C Holder and J Southgate
Cell Death Differ 16: 103-114; advance online publication, August 8, 2008; doi:10.1038/cdd.2008.116
Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells
D Kassahn, U Nachbur, S Conus, O Micheau, P Schneider, H-U Simon and T Brunner
Cell Death Differ 16: 115-124; advance online publication, September 12, 2008; doi:10.1038/cdd.2008.133
p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis
M Donaldson, A Antignani, J Milner, N Zhu, A Wood, L Cardwell-Miller, C M Changpriroa and S H Jackson
Cell Death Differ 16: 125-138; advance online publication, September 19, 2008; doi:10.1038/cdd.2008.129
Novel cell death by downregulation of eEF1A1 expression in tetraploids
Y Kobayashi and S Yonehara
Cell Death Differ 16: 139-150; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.136
Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model
E Decrock, E De Vuyst, M Vinken, M Van Moorhem, K Vranckx, N Wang, L Van Laeken, M De Bock, K D'Herde, C P Lai, V Rogiers, W H Evans, C C Naus and L Leybaert
Cell Death Differ 16: 151-163; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.138
Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3
C Tringali, B Lupo, F Cirillo, N Papini, L Anastasia, G Lamorte, P Colombi, R Bresciani, E Monti, G Tettamanti and B Venerando
Cell Death Differ 16: 164-174; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.141
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
J Thorburn, H Horita, J Redzic, K Hansen, A E Frankel and A Thorburn
Cell Death Differ 16: 175-183; advance online publication, October 10, 2008; doi:10.1038/cdd.2008.143
Meeting Report
Family at last: highlights of the first international meeting on proteins killing tumour cells
P Bruno, C R Brinkmann, M-C Boulanger, M Flinterman, P Klanrit, M-C Landry, D Portsmouth, J Borst, M Tavassoli, M Noteborn, C Backendorf and R M E Zimmerman
Cell Death Differ 16: 184-186; doi:10.1038/cdd.2008.164

