TABLE OF CONTENTS

Volume 16, Issue 1 (January 2009)

Special Issue on Autophagy in Aging, Disease and Death


Autophagy ('self-eating') is one of the most intriguing phenomena in cell biology. It is a process by which the cellular content is digested by the lysosomal machinery. Autophagy is functionally related to a diverse range of stress responses, including cell death. In this special issue of Cell Death & Differentiation, prominent scientists review the basic physiology of autophagy, as well as its implications for health and disease, in infection, immune responses, cancer, a range of organ-specific pathologies,and in age-related disorders.

See articles marked  

Top

Editorial

Autophagy in aging, disease and death: the true identity of a cell death impostor   FREE

B Levine and G Kroemer

Cell Death Differ 16: 1-2; doi:10.1038/cdd.2008.139

Top

Reviews

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009   FREE

G Kroemer, L Galluzzi, P Vandenabeele, J Abrams, E S Alnemri, E H Baehrecke, M V Blagosklonny, W S El-Deiry, P Golstein, D R Green, M Hengartner, R A Knight, S Kumar, S A Lipton, W Malorni, G Nuñez, M E Peter, J Tschopp, J Yuan, M Piacentini, B Zhivotovsky and G Melino

Cell Death Differ 16: 3-11; advance online publication, October 10, 2008; doi:10.1038/cdd.2008.150

Does autophagy have a license to kill mammalian cells?   FREE

F Scarlatti, R Granata, A J Meijer and P Codogno

Cell Death Differ 16: 12-20; advance online publication, July 4, 2008; doi:10.1038/cdd.2008.101

Autophagy and cell death in model organisms   FREE

N Kourtis and N Tavernarakis

Cell Death Differ 16: 21-30; advance online publication, August 22, 2008; doi:10.1038/cdd.2008.120

The role of autophagy in the heart   FREE

K Nishida, S Kyoi, O Yamaguchi, J Sadoshima and K Otsu

Cell Death Differ 16: 31-38; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.163

Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency   FREE

D H Perlmutter

Cell Death Differ 16: 39-45; advance online publication, July 11, 2008; doi:10.1038/cdd.2008.103

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies   FREE

S Sarkar, B Ravikumar, R A Floto and D C Rubinsztein

Cell Death Differ 16: 46-56; advance online publication, July 18, 2008; doi:10.1038/cdd.2008.110

Eating the enemy within: autophagy in infectious diseases   FREE

A Orvedahl and B Levine

Cell Death Differ 16: 57-69; advance online publication, September 5, 2008; doi:10.1038/cdd.2008.130

Autophagy and multivesicular bodies: two closely related partners   FREE

C M Fader and M I Colombo

Cell Death Differ 16: 70-78; advance online publication, November 14, 2008; doi:10.1038/cdd.2008.168

Autophagy in CD4+ T-cell immunity and tolerance   FREE

J D Lünemann and C Münz

Cell Death Differ 16: 79-86; advance online publication, July 18, 2008; doi:10.1038/cdd.2008.113

Control of autophagy by oncogenes and tumor suppressor genes   FREE

M C Maiuri, E Tasdemir, A Criollo, E Morselli, J M Vicencio, R Carnuccio and G Kroemer

Cell Death Differ 16: 87-93; advance online publication, September 19, 2008; doi:10.1038/cdd.2008.131

Autophagy genes and ageing   FREE

T Vellai

Cell Death Differ 16: 94-102; advance online publication, September 12, 2008; doi:10.1038/cdd.2008.126

Top

Original Papers

FOXA1 and IRF-1 intermediary transcriptional regulators of PPARbold italic gamma-induced urothelial cytodifferentiation

C L Varley, E J Bacon, J C Holder and J Southgate

Cell Death Differ 16: 103-114; advance online publication, August 8, 2008; doi:10.1038/cdd.2008.116

Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells

D Kassahn, U Nachbur, S Conus, O Micheau, P Schneider, H-U Simon and T Brunner

Cell Death Differ 16: 115-124; advance online publication, September 12, 2008; doi:10.1038/cdd.2008.133

p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis

M Donaldson, A Antignani, J Milner, N Zhu, A Wood, L Cardwell-Miller, C M Changpriroa and S H Jackson

Cell Death Differ 16: 125-138; advance online publication, September 19, 2008; doi:10.1038/cdd.2008.129

Novel cell death by downregulation of eEF1A1 expression in tetraploids

Y Kobayashi and S Yonehara

Cell Death Differ 16: 139-150; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.136

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model

E Decrock, E De Vuyst, M Vinken, M Van Moorhem, K Vranckx, N Wang, L Van Laeken, M De Bock, K D'Herde, C P Lai, V Rogiers, W H Evans, C C Naus and L Leybaert

Cell Death Differ 16: 151-163; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.138

Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3

C Tringali, B Lupo, F Cirillo, N Papini, L Anastasia, G Lamorte, P Colombi, R Bresciani, E Monti, G Tettamanti and B Venerando

Cell Death Differ 16: 164-174; advance online publication, September 26, 2008; doi:10.1038/cdd.2008.141

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

J Thorburn, H Horita, J Redzic, K Hansen, A E Frankel and A Thorburn

Cell Death Differ 16: 175-183; advance online publication, October 10, 2008; doi:10.1038/cdd.2008.143

Top

Meeting Report

Family at last: highlights of the first international meeting on proteins killing tumour cells

P Bruno, C R Brinkmann, M-C Boulanger, M Flinterman, P Klanrit, M-C Landry, D Portsmouth, J Borst, M Tavassoli, M Noteborn, C Backendorf and R M E Zimmerman

Cell Death Differ 16: 184-186; doi:10.1038/cdd.2008.164

Extra navigation

.

naturejobs

ADVERTISEMENT