TABLE OF CONTENTS

Volume 15, Issue 6 (June 2008)

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Reviews

Cancer stem cells – old concepts, new insights

L Vermeulen, M R Sprick, K Kemper, G Stassi and J P Medema

Cell Death Differ 15: 947-958; advance online publication, February 15, 2008; doi:10.1038/cdd.2008.20

The dark side of a tumor suppressor: anti-apoptotic p53

R U Jänicke, D Sohn and K Schulze-Osthoff

Cell Death Differ 15: 959-976; advance online publication, March 21, 2008; doi:10.1038/cdd.2008.33

Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?

V Labi, F Grespi, F Baumgartner and A Villunger

Cell Death Differ 15: 977-987; advance online publication, March 28, 2008; doi:10.1038/cdd.2008.37

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Original Papers

Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells

X-D Zhou and Y M Agazie

Cell Death Differ 15: 988-996; advance online publication, April 18, 2008; doi:10.1038/cdd.2008.54

Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur

J R Cross, A Postigo, K Blight and J Downward

Cell Death Differ 15: 997-1008; advance online publication, February 15, 2008; doi:10.1038/cdd.2008.14

The molecular archaeology of a mitochondrial death effector: AIF in Drosophila

N Joza, K Galindo, J A Pospisilik, P Benit, M Rangachari, E E Kanitz, Y Nakashima, G G Neely, P Rustin, J M Abrams, G Kroemer and J M Penninger

Cell Death Differ 15: 1009-1018; advance online publication, February 29, 2008; doi:10.1038/cdd.2008.24

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute

E M Michalak, A Villunger, J M Adams and A Strasser

Cell Death Differ 15: 1019-1029; advance online publication, February 8, 2008; doi:10.1038/cdd.2008.16

DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death

J-S Mo, M-Y Kim, E-J Ann, J-A Hong and H-S Park

Cell Death Differ 15: 1030-1041; advance online publication, February 29, 2008; doi:10.1038/cdd.2008.26

Bax siRNA promotes survival of cultured and allografted granule cell precursors through blockade of caspase-3 cleavage

S S Zhokhov, A Desfeux, N Aubert, A Falluel-Morel, A Fournier, V Laudenbach, H Vaudry and B J Gonzalez

Cell Death Differ 15: 1042-1053; advance online publication, March 7, 2008; doi:10.1038/cdd.2008.29

The SCFFSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans

M X Gao, E H Liao, B Yu, Y Wang, M Zhen and W B Derry

Cell Death Differ 15: 1054-1062; advance online publication, March 14, 2008; doi:10.1038/cdd.2008.30

BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals

C A Jette, A M Flanagan, J Ryan, U J Pyati, S Carbonneau, R A Stewart, D M Langenau, A T Look and A Letai

Cell Death Differ 15: 1063-1072; advance online publication, April 11, 2008; doi:10.1038/cdd.2008.42

The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila

F S Khan, M Fujioka, P Datta, T Fernandes-Alnemri, J B Jaynes and E S Alnemri

Cell Death Differ 15: 1073-1083; advance online publication, February 15, 2008; doi:10.1038/cdd.2008.19

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Book Review

How to study neuroprotection?

P Tucci and G Bagetta

Cell Death Differ 15: 1084-1085; doi:10.1038/cdd.2008.32

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