TABLE OF CONTENTS

Volume 15, Issue 1 (January 2008)

Special Issue on Tumor stress, cell death and the ensuing immune response

The mechanistic and phenomenological characteristics of cell death play a major role in shaping the immune response. This review series included state-of-the art reviews on the relationship between cell death and the immune system. Comprehensive articles discuss how the stress, agony and demise of virus-infected or transformed cells can determine whether the innate and cognate immune systems are activated or suppressed. Moreover, the question how cell death of immune effectors can regulate immune responses is discussed. This compendium of comprehensive review articles should serve as a key resource to researchers in immunology, cell biology, oncology, virology and pharmacology.

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Editorial

The immune response against dying tumor cells: avoid disaster, achieve cure   FREE

L Zitvogel and G Kroemer

Cell Death Differ 15: 1-2; doi:10.1038/sj.cdd.4402267

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Reviews

Molecular characteristics of immunogenic cancer cell death   FREE

A Tesniere, T Panaretakis, O Kepp, L Apetoh, F Ghiringhelli, L Zitvogel and G Kroemer

Cell Death Differ 15: 3-12; advance online publication, November 16, 2007; doi:10.1038/sj.cdd.4402269

Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all   FREE

R G van der Most, A J Currie, B W S Robinson and R A Lake

Cell Death Differ 15: 13-20; advance online publication, November 16, 2007; doi:10.1038/sj.cdd.4402255

Tumor stress, cell death and the ensuing immune response   FREE

E Ullrich, M Bonmort, G Mignot, G Kroemer and L Zitvogel

Cell Death Differ 15: 21-28; advance online publication, November 9, 2007; doi:10.1038/sj.cdd.4402266

From regulation of dying cell engulfment to development of anti-cancer therapy   FREE

D V Krysko and P Vandenabeele

Cell Death Differ 15: 29-38; advance online publication, November 16, 2007; doi:10.1038/sj.cdd.4402271

Interactions of tumor cells with dendritic cells: balancing immunity and tolerance   FREE

M V Dhodapkar, K M Dhodapkar and A K Palucka

Cell Death Differ 15: 39-50; advance online publication, October 19, 2007; doi:10.1038/sj.cdd.4402247

Killer dendritic cells: mechanisms of action and therapeutic implications for cancer   FREE

A K Wesa and W J Storkus

Cell Death Differ 15: 51-57; advance online publication, October 19, 2007; doi:10.1038/sj.cdd.4402243

The 'kiss of death' by dendritic cells to cancer cells   FREE

C W Chan and F Housseau

Cell Death Differ 15: 58-69; advance online publication, October 19, 2007; doi:10.1038/sj.cdd.4402235

T-cell death and cancer immune tolerance   FREE

B Lu and O J Finn

Cell Death Differ 15: 70-79; advance online publication, November 16, 2007; doi:10.1038/sj.cdd.4402274

Tumour-released exosomes and their implications in cancer immunity   FREE

M Iero, R Valenti, V Huber, P Filipazzi, G Parmiani, S Fais and L Rivoltini

Cell Death Differ 15: 80-88; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402237

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Original Papers

Antagonistic control of cell fates by JNK and p38-MAPK signaling FREE

T Wada, E Stepniak, L Hui, A Leibbrandt, T Katada, H Nishina, E F Wagner and J M Penninger

Cell Death Differ 15: 89-93; advance online publication, August 31, 2007; doi:10.1038/sj.cdd.4402222

The homeobox gene Arx is a novel positive regulator of embryonic myogenesis FREE

S Biressi, G Messina, P Collombat, E Tagliafico, S Monteverde, L Benedetti, M G Cusella De Angelis, A Mansouri, S Ferrari, S Tajbakhsh, V Broccoli and G Cossu

Cell Death Differ 15: 94-104; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402230

Autophagy is required for necrotic cell death in Caenorhabditis elegans  FREE

C Samara, P Syntichaki and N Tavernarakis

Cell Death Differ 15: 105-112; advance online publication, September 28, 2007; doi:10.1038/sj.cdd.4402231

An essential role for the Leishmania major metacaspase in cell cycle progression FREE

A Ambit, N Fasel, G H Coombs and J C Mottram

Cell Death Differ 15: 113-122; advance online publication, September 28, 2007; doi:10.1038/sj.cdd.4402232

Isolation and characterization of a murine resident liver stem cell FREE

A Conigliaro, M Colletti, C Cicchini, M T Guerra, R Manfredini, R Zini, V Bordoni, F Siepi, M Leopizzi, M Tripodi and L Amicone

Cell Death Differ 15: 123-133; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402236

Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A) FREE

G Kostylina, D Simon, M F Fey, S Yousefi and H U Simon

Cell Death Differ 15: 134-142; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402238

Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia FREE

M Wetzel, L Li, K M Harms, T Roitbak, P B Ventura, G A Rosenberg, R Khokha and L A Cunningham

Cell Death Differ 15: 143-151; advance online publication, October 26, 2007; doi:10.1038/sj.cdd.4402246

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO FREE

C Frelin, V Imbert, V Bottero, N Gonthier, A K Samraj, K Schulze-Osthoff, P Auberger, G Courtois and J-F Peyron

Cell Death Differ 15: 152-160; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402240

pp32/PHAPI determines the apoptosis response of non-small-cell lung cancer FREE

S Hoffarth, A Zitzer, R Wiewrodt, P S Hähnel, V Beyer, A Kreft, S Biesterfeld and M Schuler

Cell Death Differ 15: 161-170; advance online publication, October 26, 2007; doi:10.1038/sj.cdd.4402256

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells FREE

Y Chen, E McMillan-Ward, J Kong, S J Israels and S B Gibson

Cell Death Differ 15: 171-182; advance online publication, October 5, 2007; doi:10.1038/sj.cdd.4402233

Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis FREE

M Schiller, I Bekeredjian-Ding, P Heyder, N Blank, A D Ho and H-M Lorenz

Cell Death Differ 15: 183-191; advance online publication, October 12, 2007; doi:10.1038/sj.cdd.4402239

Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor FREE

S-Y Park, M-Y Jung, H-J Kim, S-J Lee, S-Y Kim, B-H Lee, T-H Kwon, R-W Park and I-S Kim

Cell Death Differ 15: 192-201; advance online publication, October 26, 2007; doi:10.1038/sj.cdd.4402242

Proliferative potential after DNA damage and non-homologous end joining are affected by loss of securin FREE

J A Bernal, M Roche, C Méndez-Vidal, A Espina, M Tortolero and J A Pintor-Toro

Cell Death Differ 15: 202-212; advance online publication, October 26, 2007; doi:10.1038/sj.cdd.4402254

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Letters to the Editor

Cytoplasmic p53 is not required for PUMA-induced apoptosis FREE

B A Callus, P G Ekert, J E Heraud, A M Jabbour, A Kotevski, J E Vince, J Silke and D L Vaux

Cell Death Differ 15: 213-215; advance online publication, November 9, 2007; doi:10.1038/sj.cdd.4402245

Response to Callus et al on 'Cytoplasmic p53 is not required for PUMA-induced apoptosis' FREE

J E Chipuk and D R Green

Cell Death Differ 15: 215-216; advance online publication, November 9, 2007; doi:10.1038/sj.cdd.4402248

Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis FREE

S A Danovi, M Rossi, K Gudmundsdottir, M Yuan, G Melino and S Basu

Cell Death Differ 15: 217-219; advance online publication, September 7, 2007; doi:10.1038/sj.cdd.4402226

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