TABLE OF CONTENTS

Volume 14, Issue 3 (March 2007)

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News and Commentaries

CD95L pro-drug: a novel Swiss Army Knife in cancer therapy? FREE

D Kassahn, U Nachbur and T Brunner

Cell Death Differ 14: 393-394; advance online publication, December 8, 2006; doi:10.1038/sj.cdd.4402069

Nuclear PTEN: a tale of many tails FREE

A Gil, A Andrés-Pons and R Pulido

Cell Death Differ 14: 395-399; advance online publication, December 22, 2006; doi:10.1038/sj.cdd.4402073

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Review

RIP1, a kinase on the crossroads of a cell's decision to live or die FREE

N Festjens, T Vanden Berghe, S Cornelis and P Vandenabeele

Cell Death Differ 14: 400-410; doi:10.1038/sj.cdd.4402085

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Original Papers

Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis FREE

T Liu, C Laurell, G Selivanova, J Lundeberg, P Nilsson and K G Wiman

Cell Death Differ 14: 411-421; advance online publication, August 18, 2006; doi:10.1038/sj.cdd.4402022

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alpha V beta 3-expressing endothelial cells FREE

A Borgne-Sanchez, S Dupont, A Langonné, L Baux, H Lecoeur, D Chauvier, M Lassalle, O Déas, J-J Brière, M Brabant, P Roux, C Péchoux, J-P Briand, J Hoebeke, A Deniaud, C Brenner, P Rustin, L Edelman, D Rebouillat and E Jacotot

Cell Death Differ 14: 422-435; advance online publication, August 4, 2006; doi:10.1038/sj.cdd.4402018

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells FREE

J Yu, V Baron, D Mercola, T Mustelin and E D Adamson

Cell Death Differ 14: 436-446; advance online publication, September 22, 2006; doi:10.1038/sj.cdd.4402029

Elucidation of some Bax conformational changes through crystallization of an antibody–peptide complex FREE

F W Peyerl, S Dai, G A Murphy, F Crawford, J White, P Marrack and J W Kappler

Cell Death Differ 14: 447-452; advance online publication, September 1, 2006; doi:10.1038/sj.cdd.4402025

Death receptor ligation triggers membrane scrambling between Golgi and mitochondria FREE

S Ouasti, P Matarrese, R Paddon, R Khosravi-Far, M Sorice, A Tinari, W Malorni and M Degli Esposti

Cell Death Differ 14: 453-461; advance online publication, September 29, 2006; doi:10.1038/sj.cdd.4402043

Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons FREE

H Yuan, A A Gerencser, G Liot, S A Lipton, M Ellisman, G A Perkins and E Bossy-Wetzel

Cell Death Differ 14: 462-471; advance online publication, October 20, 2006; doi:10.1038/sj.cdd.4402046

Genistein inhibits Brca1 mutant tumor growth through activation of DNA damage checkpoints, cell cycle arrest, and mitotic catastrophe FREE

Y Tominaga, A Wang, R-H Wang, X Wang, L Cao and C-X Deng

Cell Death Differ 14: 472-479; advance online publication, October 6, 2006; doi:10.1038/sj.cdd.4402037

Membrane-bound CD95 ligand expressed on human antigen-presenting cells prevents alloantigen-specific T cell response without impairment of viral and third-party T cell immunity FREE

G Strauss, W Osen, I Knape, E-M Jacobsen, S M Müller and K-M Debatin

Cell Death Differ 14: 480-488; advance online publication, August 11, 2006; doi:10.1038/sj.cdd.4402019

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells FREE

T Zhao, H Zhang, Y Guo, Q Zhang, G Hua, H Lu, Q Hou, H Liu and Z Fan

Cell Death Differ 14: 489-499; advance online publication, September 29, 2006; doi:10.1038/sj.cdd.4402040

Autophagy delays apoptotic death in breast cancer cells following DNA damage FREE

M J Abedin, D Wang, M A McDonnell, U Lehmann and A Kelekar

Cell Death Differ 14: 500-510; advance online publication, September 22, 2006; doi:10.1038/sj.cdd.4402039

Altered gene expression in cells from patients with lysosomal storage disorders suggests impairment of the ubiquitin pathway FREE

P Bifsha, K Landry, L Ashmarina, S Durand, V Seyrantepe, S Trudel, C Quiniou, S Chemtob, Y Xu, R A Gravel, R Sladek and A V Pshezhetsky

Cell Death Differ 14: 511-523; advance online publication, August 4, 2006; doi:10.1038/sj.cdd.4402013

Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure FREE

G I Perez, B M Acton, A Jurisicova, G A Perkins, A White, J Brown, A M Trbovich, M-R Kim, R Fissore, J Xu, A Ahmady, S G D'Estaing, H Li, W Kagawa, H Kurumizaka, S Yokoyama, H Okada, T W Mak, M H Ellisman, R F Casper and J L Tilly

Cell Death Differ 14: 524-533; advance online publication, October 13, 2006; doi:10.1038/sj.cdd.4402050

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells FREE

P Obexer, K Geiger, P F Ambros, B Meister and M J Ausserlechner

Cell Death Differ 14: 534-547; advance online publication, August 4, 2006; doi:10.1038/sj.cdd.4402017

DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells FREE

M Katayama, T Kawaguchi, M S Berger and R O Pieper

Cell Death Differ 14: 548-558; advance online publication, September 1, 2006; doi:10.1038/sj.cdd.4402030

XLX is an IAP family member regulated by phosphorylation during meiosis FREE

J Greenwood and J Gautier

Cell Death Differ 14: 559-567; advance online publication, September 29, 2006; doi:10.1038/sj.cdd.4402031

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation FREE

R Arnold, C R Frey, W Müller, D Brenner, P H Krammer and F Kiefer

Cell Death Differ 14: 568-575; advance online publication, October 6, 2006; doi:10.1038/sj.cdd.4402042

Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53 FREE

C Constantinou and M J Clemens

Cell Death Differ 14: 576-585; advance online publication, September 22, 2006; doi:10.1038/sj.cdd.4402045

Calnexin-dependent regulation of tunicamycin-induced apoptosis in breast carcinoma MCF-7 cells FREE

F Delom, A Emadali, E Cocolakis, J-J Lebrun, A Nantel and E Chevet

Cell Death Differ 14: 586-596; advance online publication, July 21, 2006; doi:10.1038/sj.cdd.4402012

Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis FREE

S-Y Choi, F Gonzalvez, G M Jenkins, C Slomianny, D Chretien, D Arnoult, P X Petit and M A Frohman

Cell Death Differ 14: 597-606; advance online publication, August 4, 2006; doi:10.1038/sj.cdd.4402020

Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration FREE

H Lin, T-Y Lin and J-L Juang

Cell Death Differ 14: 607-615; advance online publication, August 25, 2006; doi:10.1038/sj.cdd.4402033

Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity FREE

R Yamaguchi, A Andreyev, A N Murphy, G A Perkins, M H Ellisman and D D Newmeyer

Cell Death Differ 14: 616-624; advance online publication, September 15, 2006; doi:10.1038/sj.cdd.4402035

Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons FREE

K M Wright, A E Vaughn and M Deshmukh

Cell Death Differ 14: 625-633; advance online publication, August 25, 2006; doi:10.1038/sj.cdd.4402024

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Letters to the Editor

CD4/CXCR4-mediated cell death in AIDS FREE

E Ritsou, R Breitkreutz, A Benner, T Böhler, M A Weigand, H Walczak, M-L Gougeon and P H Krammer

Cell Death Differ 14: 634-636; advance online publication, November 3, 2006; doi:10.1038/sj.cdd.4402054

Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction FREE

T Kaufmann, R Gugasyan, S Gerondakis, V M Dixit and A Strasser

Cell Death Differ 14: 637-639; advance online publication, November 10, 2006; doi:10.1038/sj.cdd.4402061

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Erratum

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells FREE

J Yu, V Baron, D Mercola, T Mustelin and E D Adamson

Cell Death Differ 14: 640; doi:10.1038/sj.cdd.4402093

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