Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes

doi:doi:10.1038/sj.cdd.4402193

Cell Death and Differentiation (2007) 14, 1842–1844; doi:10.1038/sj.cdd.4402193; published online 6 July 2007

Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes

Z Sarang¹, A Mádi^1,2, C Koy², S Varga³, M O Glocker², D S Ucker⁴, S Kuchay⁵, A H Chishti⁵, G Melino⁶, L Fésüs¹ and Z Szondy¹

¹Department of Biochemistry and Molecular Biology, Signaling and Apoptosis Research Group, Hungarian Academy of Sciences, University of Debrecen, Debrecen H-4012, Hungary
²Proteome Center Rostock, Medical Faculty, University of Rostock, Rostock D-18055, Germany
³Clinical Research Center, Laboratory for Electron Microscopy, University of Debrecen, Debrecen H-4012, Hungary
⁴Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL 60612, USA
⁵Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA
⁶Fondazione S Lucia, Roma, Italy and Medical Research Council, Toxicology Unit, Hodgkin bld, Leicester LE1 9HN, UK

Correspondence: Z Szondy, Department of Biochemistry and Molecular Biology, University of Debrecen, Nagyerdei krt.98., Debrecen H-4012, Hungary. Tel: +36 52 416432; Fax: +36 52 314989; E-mail: szondy@indi.dote.hu

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