TABLE OF CONTENTS

Volume 12, Issue 9 (September 2005)

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Editorial

Discovery of the ubiquitin proteasome system and its involvement in apoptosis FREE

G Melino

Cell Death Differ 12: 1155-1157; doi:10.1038/sj.cdd.4401740

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Interviews

Early work on the ubiquitin proteasome system, an interview with Avram Hershko FREE

A Hershko

Cell Death Differ 12: 1158-1161; doi:10.1038/sj.cdd.4401709

Early work on the ubiquitin proteasome system, an interview with Irwin Rose FREE

I Rose

Cell Death Differ 12: 1162-1166; doi:10.1038/sj.cdd.4401700

Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover FREE

A Ciechanover

Cell Death Differ 12: 1167-1177; doi:10.1038/sj.cdd.4401691

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Reviews: Nobel Lectures

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting FREE

A Ciechanover

Cell Death Differ 12: 1178-1190; doi:10.1038/sj.cdd.4401692

The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle FREE

A Hershko

Cell Death Differ 12: 1191-1197; doi:10.1038/sj.cdd.4401702

Ubiquitin at Fox Chase FREE

I Rose

Cell Death Differ 12: 1198-1201; doi:10.1038/sj.cdd.4401710

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News and Commentaries

Nitrosative and oxidative stress links dysfunctional ubiquitination to Parkinson's disease FREE

Z Gu, T Nakamura, D Yao, Z-Q Shi and S A Lipton

Cell Death Differ 12: 1202-1204; doi:10.1038/sj.cdd.4401705

IAPs – the ubiquitin connection FREE

D L Vaux and J Silke

Cell Death Differ 12: 1205-1207; doi:10.1038/sj.cdd.4401696

Ubiquitylation in apoptosis: DIAP1's (N-)en(d)igma FREE

M Ditzel and P Meier

Cell Death Differ 12: 1208-1212; doi:10.1038/sj.cdd.4401711

Proteases, proteasomes and apoptosis: breaking Ub is hard to do FREE

R C Taylor, C Adrain and S J Martin

Cell Death Differ 12: 1213-1217; doi:10.1038/sj.cdd.4401703

Caspase inactivation of the proteasome FREE

G M Cohen

Cell Death Differ 12: 1218; doi:10.1038/sj.cdd.4401693

Serine proteases and calpains fulfill important supporting roles in the apoptotic tragedy of the cellular opera FREE

P Vandenabeele, S Orrenius and B Zhivotovsky

Cell Death Differ 12: 1219-1224; doi:10.1038/sj.cdd.4401719

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Original Papers

Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor FREE

J F Kucharczak, M J Simmons, C S Duckett and C Gélinas

Cell Death Differ 12: 1225-1239; advance online publication, June 17, 2005; doi:10.1038/sj.cdd.4401684

Caspase activation and apoptosis in response to proteasome inhibitors FREE

C J Henderson, E Aleo, A Fontanini, R Maestro, G Paroni and C Brancolini

Cell Death Differ 12: 1240-1254; doi:10.1038/sj.cdd.4401729

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Book Review

Proteasome inhibitors in cancer therapy: death by indigestion FREE

M Rossi, A Oberst, A Emre Sayan and P Salomoni

Cell Death Differ 12: 1255-1257; doi:10.1038/sj.cdd.4401701

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