FIGURE 2
FROM:
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
T M Ganten, T L Haas, J Sykora, H Stahl, M R Sprick, S C Fas, A Krueger, M A Weigand, A Grosse-Wilde, W Stremmel, P H Krammer and H Walczak
BACK TO ARTICLEFigure 2.
Sensitisation of Hep3b cells for TRAIL-induced apoptosis with chemotherapeutic drugs. (a) Hep3b cells (black bars) and HepG2-TR cells (grey bars) were treated with different chemotherapeutic drugs at the indicated concentrations for 24 h in the presence or absence of 1 
g/ml TRAIL. Apoptosis was determined by subdiploid DNA content. (b) HepG2 cells were treated with different concentrations of TRAIL in the presence (
) or absence (
) of 5-FU (25 g/ml). After 24 h, cell survival was analysed by MTT assay as described in Materials and methods. Data are shown as the mean
S.D. of three independent experiments