Bone Marrow Transplantation

TABLE 1

FROM:

Selection of cord blood unit(s) for transplantation

D A Wall and K W Chan

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Table 1. Minimum cell doses based on hematopoietic measurement and the effect of higher cell dose on transplant outcomes for unrelated donor CB transplant

Author Engraftment rate Cell dose (kg) recommended Effect of higher cell dose noted on
Rubinstein and Stevens37 (n=861)93%>2.5 times 107 TNCup arrow engraftment, down arrowTRM
Wagner et al. 38 (n=102)88%>1.7 times 105 CD34up arrow engraftment, down arrowTRM, up arrow survival
Migliaccio et al. 32 (n=204)NA>5 times 104 CFCup arrow engraftment, down arrowTRM
Barker et al. 39 (n=608)NA>2.5 times 107 TNCdown arrowTRM

 Abbreviations: CB=cord blood; NA=not reported.

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