TABLE 2
FROM:
Reduced intensity conditioning and allogeneic stem cell transplantation in childhood malignant and nonmalignant diseases
P Satwani, N Cooper, K Rao, P Veys and P Amrolia
BACK TO ARTICLETable 2. Primary immunodeficiencies treated with RIC-SCT
| WASP deficiency | |
| CD40 ligand deficiency | |
| XLP | |
| Hemophagocytic syndromes | |
| Immunodeficiency with partial albinism | |
| Familial HLH | |
| Griscelli disease | |
| Chediak–Higashi syndrome | |
| Phagocytic cell disorders | |
| Schwachman's syndrome | |
| Granule deficiency | |
| LAD | |
| X-linked/AR CGD | |
| Kostmann's syndrome | |
IFN- receptor deficiency | |
| Other | |
| Autoimmune/immune dysregulatory | |
| ALPS, IPEX | |
| Other | |
| Severe combined immunodeficiency (SCID) | |
| Functional | Genetic |
| T- B- NK- | ADA deficiency |
| Reticular dysgenesis | |
| T- B- NK+ | RAG deficiency |
| SCID with Artemis | |
| T- B+ NK- | deficiency (X-linked) |
| Jak 3 kinase deficiency (AR) | |
| T- B+ NK+ | IL7 R deficiency |
| Unspecified | |
| Other | |
| T-cell immunodeficiency/SCID variants | |
| CD4 lymphopenia | |
| Zap 70 kinase deficiency | |
| MHC class II deficiency | |
| PNP deficiency | |
| Omenn's syndrome | |
| Severe DiGeorge complex (22q 11del) | |
| CID with skeletal dysplasia | |
| Cartilage hair hypoplasia |
Abbreviations: ADA=adenosine deaminase deficiency; ALPS=autoimmune lymphoproliferative syndrome; AR CGD=chronic granulomatous disease; CID=combined immunodeficiency disease; HLH=hemophagocytic lymphohistiocytosis; IFN=interferon; IPEX=immune dysregulation, polyendocrinopathy and enteropathy, X-linked; LAD=leukocyte adhesion deficiency; RAG=recombinase activating gene; RIC=reduced intensity conditioning; MHC=major histocompatibility complex; PNP=purine nucleoside phosphorylase; SCT=stem cell transplantation; WASP=Wiskott–Aldrich syndrome protein; XLP=X-linked lymphoproliferative disorder.
