Bone Marrow Transplantation

TABLE 4

FROM:

Results of donor lymphocyte infusions for relapsed myelodysplastic syndrome after hematopoietic cell transplantation

P V Campregher, T Gooley, B L Scott, C Moravec, B Sandmaier, P J Martin, H J Deeg, E H Warren and M E D Flowers

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Table 4. Summary of previous reports and current series of treatment with DLI for recurrent MDS

Study No. of patients Donor type Median age Median months from transplant to relapse DLI cell dose kg -1 (median) Complete response (%)
Current series1612 MRD/4 MUD4871 times 108 CD3+3/14 (20)
Depil et al. 7 1413 MRD/1 MUD46106.3 times 107 CD3+2/14 (14)
Shiobara et al. 14 1110 MRD/1 MMUD2483.9 times 108 TNC3/11 (27)
Ho et al. 19 106 MRD/4 MUD53NA0.8 times 107 CD3+4/10 (40)
Collins et al. 10 66 MRD40NA7.3 times 108 MNC2/5 (40)
Kolb et al. 11 55 MRD39127.6 times 108 MNC1/4 (25)

 Abbreviations: MRD=matched related donors; MUD=matched unrelated donors; NA=not available.

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