Bone Marrow Transplantation

TABLE 2

FROM:

Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation: joint recommendations of the European Group for Blood and Marrow Transplantation, Center for International Blood and Marrow Transplant Research, and the American Society for Blood and Marrow Transplantation (EBMT/CIBMTR/ASBMT)

J D Rizzo, J R Wingard, A Tichelli, S J Lee, M T Van Lint, L J Burns, S M Davies, J L M Ferrara and G Socié

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Table 2. EBMT–CIBMTR–ASBMT abbreviated summary recommendations for screening and prevention in long-term HCT survivors organized by time after transplantation

Recommended screening/prevention 6 months 1 year Annually
Immunity    
 Encapsulated organism prophylaxis333
 PCP prophylaxis133
 CMV testing33 
 Immunizations 11
 
Oral complications    
 Dental assessment111
 
Liver    
 Liver function testing11+
 Serum ferritin testing 1+
 
Respiratory    
 Clinical pulmonary assessment111
 Smoking tobacco avoidance111
 Pulmonary function testing 2+
 Chest radiography+++
 
Endocrine    
 Thyroid function testing 1+
 Growth velocity children 11
 Gonadal function assessment (pre-pubertal men and women)111
 Gonadal function assessment (post-pubertal women) 11
 
Ocular    
 Ocular clinical symptom evaluation111
 Schirmer's testing 33
 Ocular fundus exam 1+
 
Skeletal    
 Bone density testing (women and patients with prolonged corticosteroid, calcineurin use) 1+
 
Second cancers    
 Second cancer vigilance counseling 11
 Breast/skin/testes self-exam 11
 Clinical screening second cancers 11
 Pap smear/mammogram (over age 40 years) 11
 
Nervous system    
 Neurologic clinical evaluation 1+
 
Kidney    
 Blood pressure screening111
 Urine protein screening11+
 BUN/creatinine testing111
 
Vascular    
 Cardiovascular risk factor assessment 11
 
Psychosocial    
 Psychosocial/QOL clinical assessment111
 Sexual function assessment111

 1=Recommended for all transplant patients.

 2=Recommended for allogeneic patients only.

 3=Recommended for any patient with ongoing cGVHD or immunosuppression.

 +=Reassessment recommended for abnormal testing in a previous time period or new signs/symptoms.

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