Bone Marrow Transplantation

TABLE 2

FROM:

What would Karl Landsteiner do? The ABO blood group and stem cell transplantation

J M Heal, J L Liesveld, G L Phillips and N Blumberg

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Table 2. Limitations of studies of ABO nonidentical transplants and transfusions

Figure and tables index
Stem cell transplantation
 No randomized controlled trials of ABO identical vs nonidentical donors as the graft source, nor the relative importance of ABO vs minor HLA mismatching
 Studies do not differentiate between identical and nonidentical transplants, but employ various red cell transfusion-based definitions of 'compatibility' that may not be applicable to stem cell transplants
 
Transfusion studies
 Randomized trials involve induction therapy for acute leukemia in adults, but not stem cell transplantation or other diseases or pediatrics
 Randomized trials of ABO mismatching employed nonleukoreduced transfusions
Figure and tables index
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