Bone Marrow Transplantation

TABLE 2

FROM:

GI complications in pediatric patients post-BMT

C C Barker, R A Anderson, R S Sauve and J D Butzner

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Table 2. Means and standard deviations of the highest hepatic laboratory values recorded post transplantation for the transplants that developed hepatic graft-versus-host disease (GVHD), veno-occlusive disease (VOD) and 'other' (hepatic dysfunction without GVHD or VOD complications)

Variable 'Other' hepatic dysfunction (n=90) Hepatic GVHD (n=24) Hepatic VOD (n=13)
ALT (IU/l)122plusminus149430plusminus987a 726plusminus1061a
AST (IU/l)125plusminus171311plusminus962a 1481plusminus2572a
GGT (IU/l)166plusminus205255plusminus140a 572plusminus1147a
Alkaline phosphatase (IU/l)190plusminus122202plusminus120286plusminus290a
Bilirubin (mumol/l)22plusminus2349plusminus31a 223plusminus226a , b

 The 15 transplants that did not develop any hepatic dysfunction are not recorded in this table.

a A comparison of means between the groups found a significant difference between the 'other' group and the hepatic GVHD or the VOD group (P<0.05).

b A significant difference was found between the hepatic GVHD group and VOD group (P<0.05).

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