Quality of Life

Bone Marrow Transplantation (2005) 35, 1113–1116. doi:10.1038/sj.bmt.1704963 Published online 11 April 2005

Poor nutritional status prior to peripheral blood stem cell transplantation is associated with increased length of hospital stay

P Horsley1, J Bauer2 and B Gallagher1

  1. 1The Wesley Hospital, Brisbane, Australia
  2. 2The Wesley Research Institute, Brisbane, Australia

Correspondence: Dr J Bauer, Bank of Queensland Medical Research Fellow, The Wesley Research Institute, PO Box 499, Toowong, Queensland 4066, Australia. E-mail: judithba@wesley.com.au

Received 18 November 2004; Accepted 10 February 2005; Published online 11 April 2005.

Top

Abstract

The nutritional status of patients prior to peripheral blood stem cell transplantation (PBSCT) and its impact on length of hospital stay is not well described in the literature. The nutritional status of 66 consecutive patients (46 m:20 f); and the mean age 58.7plusminus12.0 years was determined a maximum of 2 weeks pre-transplantation using the scored Patient-Generated-Subjective Global Assessment (PG-SGA). According to the global assessment, 73% patients were well nourished, 23% moderately malnourished and 4% severely malnourished. There was a significant difference in post transplant length of stay (mean differenceplusminuss.e.m. -7.0plusminus2.1 days) between well-nourished and malnourished patients and a trend towards higher mortality in the malnourished group (2 vs 20%). Although 89% of patients described no problems eating, two or more nutrition impact symptoms were reported in 30% of patients. From stepwise multiple regression analysis, nutritional status as determined by PG-SGA score was significantly associated with length of stay, accounting for 12% of the variance. In conclusion, malnutrition prior to PBSCT is associated with increased length of stay. Routine nutrition assessment of patients prior to PBSCT should be undertaken.

Keywords:

nutrition assessment, Patient-Generated Subjective Global Assessment, malnutrition, peripheral blood stem cell transplantation

Top

MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated

REVIEWS

Nutritional support in patients with chronic liver disease

Nature Clinical Practice Gastroenterology & Hepatology Review (01 Apr 2006)

See all 7 matches for Reviews

Extra navigation

.

naturejobs

ADVERTISEMENT