Case Report
Bone Marrow Transplantation (2004) 33, 451–453. doi:10.1038/sj.bmt.1704370 Published online 29 December 2003
Autologous blood pleurodesis for pneumothorax complicating graft-versus-host disease-related bronchiolitis obliterans
C Chadwick1, S M Marven1 and A J Vora1
1Paediatric Surgical Unit & Department of Paediatric Haematology, Sheffield Children's Hospital, Sheffield, UK
Correspondence: Dr AJ Vora, Sheffield Children's Hospital, Western Bank, Sheffield S10 1TH, UK. E-mail: ajay.vora@sch.nhs.uk
Received 9 August 2002; Accepted 23 June 2003; Published online 29 December 2003.
Abstract
Bronchiolitis obliterans (BO) is a manifestation of chronic graft-versus-host disease (GVHD) after allogeneic haemopoietic stem cell transplantation. Complications associated with this include persistent air-leak syndromes such as pneumothorax. Many methods have been described for treating this condition, both surgical and nonsurgical. We describe an 8-year-old boy with acute lymphoblastic leukaemia complicated by chronic GVHD-related BO, and subsequent pneumothorax with persistent air leak, who was treated successfully with autologous blood pleurodesis.
Keywords:
pneumothorax, blood, pleurodesis, graft-versus-host, child
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