TABLE 2
FROM:
Cytoreduction with iodine-131-anti-CD33 antibodies before bone marrow transplantation for advanced myeloid leukemias
J M Burke, P C Caron, E B Papadopoulos, C R Divgi, G Sgouros, K S Panageas, R D Finn, S M Larson, R J O'Reilly, D A Scheinberg and J G Jurcic
BACK TO ARTICLETable 2. Pharmacokinetics and biodistribution of 131I-M195
| Marrow | Liver | Spleen | Whole body t1/2 (h) | ||||
|---|---|---|---|---|---|---|---|
| % ID/g a | t 1/2 (h) | % ID | t 1/2 (h) | % ID | t 1/2 (h) | ||
| All patients (n=8) | 0.011 0.002 | 59 19 | 7.2 3.5 | 38 12 | ND | ND | 56 13 |
| AML (n=3) | 0.01 0 | 59 31 | 10.0 4.4 | 31 11 | ND | ND | 52 12 |
| CML (n=5) | 0.012 0.003 | 59 11 | 5.5 1.6 | 42 13 | 3.7 0.8 | 36 9 | 58 14 |
Values are shown as means
s.d. ND=not done.
a % ID/g was estimated by extrapolation to time of injection for marrow.
