Case Report
Bone Marrow Transplantation (2003) 31, 211–213. doi:10.1038/sj.bmt.1703820
Lymphoid blast crisis of chronic myelogenous leukemia occurring more than 11 years after receiving an allogeneic bone marrow transplant for chronic myelogenous leukemia in myeloid blast crisis at onset
K Fukuno1,2, H Tsurumi2, T Yamada1, M Oyama1, T Matsuyama3, S Terakura4, Y Kodera4 and H Moriwaki2
- 1Department of Internal Medicine, Kisogawa Hospital, Aichi, Japan
- 2First Department of Internal Medicine, Gifu University School of Medicine, Gifu, Japan
- 3Department of Pediatrics, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan
- 4Department of Internal Medicine, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan
Correspondence: Dr H Moriwaki, First Department of Internal Medicine, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan
Received 16 November 2001; Accepted 12 April 2002.
Abstract
A 25-year-old male developed lymphoid blast crisis (BC) of chronic myelogenous leukemia (CML) more than 11 years after receiving an allogeneic bone marrow transplant (alloBMT) for CML with myeloid BC at presentation from his HLA-identical brother. The lymphoid BC of CML probably occurred without a preceding chronic phase of CML. This case illustrates the difficulties involved in determining the appropriate length of follow-up after alloBMT.
Keywords:
chronic myelogenous leukemia, bone marrow transplant, late relapse, lymphoid blast crisis, acute lymphoblastic leukemia
