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  • Special Report
  • Published:

Hematopoietic stem cell transplantation activity in Europe 1999

Abstract

This survey on transplantation of hematopoietic stem cells from blood or bone marrow in Europe, the 10th in a series, reports the numbers of transplants performed in 1999 and concentrates on changes in indications and donor types. Members of the European Group for Blood and Marrow Transplantation and associated teams are invited every year to report their transplant numbers by indication, donor type and stem cell source. In 1999, a total 21 430 transplants were performed by 580 teams in 35 European countries. Of these transplants 18 720 were first transplants, 5879 (31%) allogeneic, 12 841 (69%) autologous; an additional 562 allogeneic and 2148 autologous transplants were re- or multiple transplants. Ninety-five percent of the autologous transplants and 45% of the allogeneic transplants were peripheral blood stem cell transplants. A total of 103, respectively 1.8% of the allogeneic transplants, were cord blood cell transplants. Main indications in 1999 were leukemias with 6289 transplants (34%), 70% thereof allogeneic transplants; lymphomas with 8219 transplants (44%), 92% thereof autologous transplants; solid tumors with 3302 transplants (18%), 99% thereof autologous transplants; nonmalignant disorders with 715 transplants (4%), 85% thereof allogeneic transplants. Absolute numbers of allogeneic transplants continued to increase as in previous years by 10%, in contrast, there was for the first time in 10 years a decrease in autologous transplants, mainly for solid tumors. Reasons therefore are discussed. These data reflect the most recent changes in utilisation and document current status of blood and marrow transplantation in Europe. Bone Marrow Transplantation (2001) 27, 899–916.

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Acknowledgements

The co-operation of all participating teams and their staff (listed in the appendix), the EBMT secretariat (A Urbano-Ispizua, A Baur), the European EBMT Data Office in Paris (V Chesnels, P Palut, NC Gorin), the EBMT Registry Subcommittee (P Ljungman, C Ruiz de Elvira), the French Registry SFGM (JP Vernant, M-L Tanguy), the Dutch Registry (T de Witte, A v Biezen, N Tazelaar), the Austrian Registry (D Niederwieser, B Gritsch), the Italian Registry (M Vignetti, A Bacigalupo, R Oneto, C Palazzi), the German Registry (H Ottinger, C Müller, B Kubanek, N Schmitz, UW Schaefer), the Swiss Registry (J Passweg, H Baldomero), the British Registry (A Eades), the Belgium Registry, (Y Beguin), and the Spanish Transplantation Office (ONT) (M Naya) is greatly appreciated. The authors also thank A Maerki for excellent secretarial assistance, as well as L John and O Baldomero for technical assistance with data management. The work was supported in part by a grant from the Swiss National Research Foundation, 32–52756.97, and the Swiss Cancer League. EBMT is supported by grants from the corporate members: Hoffmann-La Roche Ltd, Amgen Europe, Chugai Rhone-Poulenc Rorer, Baxter, Astra, Cobe International, Nextar, Liposome Co, Imtix, Octapharma, Stem Cell Technologies, ICN Pharmaceuticals and Bristol-Meyers Squibb.

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Consortia

Appendix 1999

Appendix 1999

List of transplant centers and numbers of patients with first transplants only performed in 1999 (numbers in brackets show total number of transplants followed by allografts/autografts)

Albania: no report

Andorra: no report

Armenia: no report

Austria (14 teams; 311, 98/213)

Graz, University Hospital, CIC 308, W Linkesch, (43, 11/32)

Graz, University Hospital, Onco, CIC 278, H Samonigg, M Schmid (9, 0/9)

Graz, Universitäts-Kinderklinik, CIC 593, Ch Urban (8, 5/3)

Innsbruck, Universitätsspital (hem, onco), CIC 271, G Gastl, D Nachbaur (34, 15/19)

Klagenfurt, General Hospital Klagenfurt CIC 716, D Geissler, M Heistinger (0, 0/8)

Linz, 1 Medizinische Abteilung, AO Krankenhaus, MA Fridrik (5, 0/5)

Linz, AOK der Elisabethinen, CIC 594, D Lutz (38, 7/31)

Salzburg, LKA Salzburg (Onco), CIC 356, Prof Hausmaninger (10, 0/10)

Vienna-Lainz, Krankenhaus der Stadt Wien-Lainz, 5 Med Onko, CIC 362, G Baumgartner, E Ulsperger, Dr Mayer (5, 0/5)

Vienna, St Anna Kinderspital, CIC 528, H Gadner, C Peters (23, 14/9)

Vienna, Donauspital, CIC 767, W Hinterberger (10, 0/10)

Vienna, Universitätsklinik für Innere Medizin I-AKH, CIC 227, HT Greinix, P Kalhs (87, 43/33)

Vienna, Wilhelminerspital, CIC 828, H. Ludwig (18, 3/15)

Vienna, Hanusch-Krankenhaus, CIC 743, R. Raisner, E. Pittermann (13, 0/13)

Azerbaijan: no report

Republic of Belarus (3 teams; 56, 16/40)

Minsk, Belorussian Center, CIC 591, O Aleinikova (23, 8/15)

Minsk, Hospital No 9, CIC 801, N Milanovitch (33, 8/25)

Minsk, Institute of Haematology, CIC 326, V Ivanov ()*

Belgium (25 teams; 497; 133/364)

Aalst, OLV Ziehenhuis, E Wouters ()*

Antwerpen, AZ Middelheim, CIC 783, R de Bock (7, 0/7)

Antwerpen, Stuivenberg ZH, CIC 339, P Zachée (21, 0/21)

Brugge, AZ St Jan, CIC 506, D Selleslag, A Van Hoof, (39, 16/23)

Brussels, Children's University Hospital, CIC 644, C Devalck, E Sariban (6, 0/6)

Brussels, Clinique Général Saint Jean, CIC 779, C Dubois, (2, 0/2)

Brussels, Hôpital Erasme, CIC 596, W Feremans (13, 0/13)

Brussels, Clinique universitaire St Luc (Adults), CIC 234, A Ferrant (44, 17/27)

Brussels, Institut Jules Bordet, CIC 215, D Bron (47, 17/30)

Brussels, University Hospital, CIC 630, B van Camp, A Schots (28, 15/13)

Brussels, Cliniques Universitaires St Luc, (onco), M Symann (4, 0/4)**

Brussels, Inst Edith Cavelle Marie Depage (onco), C Vanhaelen ()*

Brussels, Clinique Universitaire St Luc (peds), CIC 234, C Vermylen (11, 6/5)

Charleroi, Hopital Notre-Dame, M André (22, 2/20)

Edegem, University Antwerpen, CIC 648, W Schroyens (25, 4/21)

Gent, University Hospital, CIC 744, LA Noens (39, 20/19)

Haine St Paul, Hôpital de Jolimont, CIC 234, A Delannoy, C Ravoet (6, 0/6)

Hasselt, Virgajesse Ziekenhuis CIC 632, D Vanstraelen, Dr Janssen (25, 0/25)

Jumet, Hôpital Civil de Jumet, A Duvivier ()*

Leuven, University Hospital Gasthuisberg, CIC 209, MA Boogaerts, J Maertens, P Vandenberghe (68, 15/53)

Liège, University Hospital Sart-Tilman, CIC 726, Y Béguin (43, 19/24)

Liège, CHR-Citadelle, CIC 353, B De Prijck (10, 0/10)

Liège, Centre Hospitalier St Joseph (hem), L Longree ()*

Roeselare, H Hartziekenhuis, Van Aelst, J Tytgat, J Demol (17, 0/17)

Yvoir, Clinique universitaire de Mont-Godinne CIC 234, C Doyen (24, 2/22)

Bosnia-Herzegovina: no report

Bulgaria (1 team; 10, 0/10)

Sofia, Uni Hospital ‘Queen Johanna’, CIC 346, (peds hem-onco), D Bobev (10, 0/10)

Croatia (2 teams; 79, 22/57)

Zagreb, Hospital Merkur, B Jaksic (21, 1/20)

Zagreb, Clinical Hospital Center, CIC 302, B Labar, D Nemet, M Mrsic (58, 21/37)

Cyprus (1 team; 12, 0/12)

Nicosia Makarious Hospital III, N Papaminas (12, 0/12)

Czech Republic (10 teams; 417, 81/336)

Brno, Masaryk University Hospital, CIC 597, J Vorlicek (85, 13/72)

Hradec Kralovè, Charles University, CIC 729, S Filip, M Blaha (53, 6/47)

Olomouc, University Hospital, CIC 574, K Indràk (44, 0/44)

Pilsen, Faculty Hospital, CIC 718, V Koza (73, 22/51)

Prague, Thomayer Memorial Hospital, CIC 375, J Abrahamova, J Nepomucka, L Boublikova (11, 0/11)

Prague, University Hospital Motol (peds onco), P Kavan (27, 0/27)

Prague, Clinical Haematology, Charles University, CIC 318, T Kozak (35, 0/35)

Prague, University Hospital Motol (peds hem), J Stary (19, 18/1)

Prague, Charles University, CIC 745, M Trneny (43, 0/43)

Prague, Institute of Hematology and Blood Transfusion, CIC 656, A Vitek, P Kobylka (27, 22/5)

Denmark (3 teams; 188, 38/150

Aarhus, Amtssygehus, CIC 634, A Boesen (62, 0/62)

Copenhagen, Rigshospitalet, CIC 206, N Jacobsen (85, 38/47)

Copenhagen, Herlev Hospital, University, CIC 568, HE Johnson (41, 0/41)

Estonia (1 team; 14, 1/13)

Tartu, University Hospital, CIC 746, H Everaus (14, 1/13)

Finland (6 teams; 221, 87/134)

Helsinki, University Hospital, Dept Oncology, CIC 833, H Joensuu, T Wiklund (14, 0/14)

Helsinki, University Hospital, Third Dept of Medicine, CIC 515, T Ruutu (85, 55/30)

Helsinki, Children's Hospital, CIC 219, U Pihkala, S Vettenranta (26, 18/8)

Kuopio, Department of Medicine, University Hospital, E Jantunen, T Nousiainen (27, 0/27)

Tampere, University Hospital, CIC 635, M Lehtinen (27, 0/27)

Turku, University Central Hospital, CIC 225, K Remes (42, 14/28)

France (83 teams; 2870, 687/2183)

Amiens, CHU d'Amiens, B Desablens, ()*

Angers, Paul Papin, Dr Gamelin (3, 0/3) SFGM

Angers, Centre Hospitalier, CIC 650, N Ifrah 53, 10/43)

Argenteuil, Centre Hospitalier, M Urbajtel (27, 5/22)

Besançon, Hôpital Jean Minjoz and Hôpital St Jacques (adults and peds), CIC 233, P Hervé, J-Y Cahn, MN Cailleux, Dr Surowka (73, 24/49)

Bobigny, Hôpital Avicenne (hem), P Casassus ()*

Bordeaux, CHU Hôpital de Bordeaux Enfants, Y Perely ()*

Brest, Centre Hospitalier, C Berthou (49, 0/49)

Caen, Hôpital Cote de Nacre (peds hem onco), P Boutard (4, 0/4)

Caen, Centre Hospitalier Régional, CIC 251, O Reman (13, 0/13)

Caen, Centre Régional François Baclesse, AM Peny (21, 0/21)

Clermont Ferrand, Hotel Dieu (peds), F Démeocq (44, 4/40) SFGM

Clermont Ferrand, Centre Jean Perrin, CIC 273, J-O Bay, (65, 8/57)

Clichy, Hôpital Beaujon, J Brière (20, 0/20) SFGM

Colmar, Hôpital civil, B Audhuy (1, 0/1) SFGM

Corbeil Essonne, Hôpital Gilles de Corbeil, A Devidas (5, 0/5)

Créteil, Hôpital H Mondor, CIC 252, C Cordonnier, M Kuentz (56, 23/33)

Dijon, Hôpital d'Enfants, D Caillot (52, 0/52)

Grenoble, Centre Hospitalier (ads, allo peds), CIC 270, JJ Sotto, L Molina, F Nicolini (52, 18/34)

Grenoble, Centre Hospitalier (auto peds), D Plantaz, M Bost (4, 0/4)

Lille, Hôpital Claude Huriez, CIC 277, F Bauters, JP Jouet (134, 45/89)

Lille, Hôpital Jeanne de Flandre, Dr Nelken (3, 0/3)

Lille, Centre Oscar Lambret (onco), Dr Depadt, Dr Defachelles (17, 0/17)

Limoges, Centre Hospitalier Dupuytren (ads), CIC 977, D Bordessoule, P Turlure (41, 0/41) SFGM

Limoges, Centre Hospitalier Dupuytren (peds), Prof De Lumley (4, 2/2)

Lyon Sud (Pierre Benite), Centre Hospitalier, B Coiffier (95, 0/95)**

Lyon, Hôpital Edouard Herriot, CIC 671, D Fiere, E Archimbaud, A Belhabri, M Michallet (76, 37/39)

Lyon, Centre Léon Bérard, CIC 241, P Biron, T Philip (69, 0/69)

Lyon, Hôpital Debrousse, CIC 806, N Phillipe, G Souillet (24, 23/1)

Marseille, Inst Paoli-Calmettes, CIC 230, D Blaise (220, 34/186)

Marseille, Hôpital d'Enfants de la Timone (onco), CIC 301, C Coze (8, 0/8)

Marseille, Hôpital d'Enfants de la Timone, G Michel (18, 15/3)

Meaux, Centre Hospitalier de Meaux, C Soussain (8, 0/8)

Metz, Thionville Hôpital Notre-Dame de Bon-Secours (hem), V Dorvaux (21, 0/21)**

Montpellier, CHU de Montpelier Hôpital Arnaud de Villeneuve, F Bernard ()*

Montpellier, Centre Rég De Lutte contre de Cancer, M Fabbro, J-B Dubois (21, 0/21)

Montpellier, CHR Lapeyronie, JF Rossi (78, 10/68)

Mulhouse, Hôpital du Hasenrain, Ph Hénon, Dr Becker (9, 0/9) SFGM

Nantes, Hotel Dieu, CIC 253, JL Harousseau, N Milpied (116, 34/82)

Nice, Hôpital de Cimiez, CIC 523, JG Fuzibet, JP Cassuto, N Gratecos (24, 10/14)

Nice, Fondation Lenval (peds), Dr Soler, Dr De Ricaud (1 patient transplanted in Marseille 1, 1/0)

Nice, Centre Antoine Lacassagne, A Thyss (21, 0/21)

Paris, Hôpital Laennec, JM Andrieu, C Le Maignan (5, 0/5)

Paris, Hôpital d'Instruction des Armées Percy, Clamart, T de Revel, G Nedellec (24, 6/18)

Paris, Hôpital Cochin, J-P Levy, F Dreyfus (25, 0/25)

Paris, Hôpital Necker des enfants malades, CIC 210, A Fischer (44, 39/5)

Paris, Hôpital St Antoine, CIC 213, C Gorin, L Fouillard (35, 5/30)

Paris, Hôpital St Louis (auto), CIC 805, G Gisselbrecht (60, 0/60)

Paris, Hôpital St Louis (allo), CIC 207, E Gluckman (75, 74/1)

Paris, Hôpital St Louis (peds), CIC 748, A Baruchel, M-F Auclerc (7, 2/5)

Paris, Hôpital St Louis (auto immuno-Haem), CIC 969, J-C Brouet, B Royer, J-P Fermand (74, 0/74)

Paris, Hôpital St Louis (auto-leuk), CIC 960, H Dombret, L Degos, P Rousselot (8, 0/8)

Paris, Hôpital Pitié Salpétière (onco), CIC 262, D Khayat (2, 0/2)

Paris, Hôpital Pitié Salpétière, CIC 262, J-P Vernant, V Leblond (82, 22/60)

Paris, Hôpital d'enfants Armand-Trousseau, G Leverger, A Auvrignon (16, 0/16)

Paris, Hôpital Tenon, JP Lotz (22, 0/22)

Paris, Hôpital Robert Debré, P Rohrlich, E Vilmer (22, 20/2)

Paris, Hôpital Necker (ads), CIC 201, B Varet, C Bélanger, A Veil (53, 28/25)

Paris, Hôtel Dieu (hem), CIC 222, J-P Marie, B Rio (36, 11/25)

Paris, Hotel Dieu (onco), Prof Bernadou, L Chauvenet (1, 0/1)

Paris, Institut Curie (ads/onco/peds), CIC 702, P Pouillart, J Michon, JM Zucker (41, 0/41)

Pessac, Hôpital Haut-Lévèque, CIC 267, J Reiffers, Dr Fabères (108, 29/79)

Poitiers, Hôpital Jean Bernard, CIC 264, A Sadoun (45, 7/38) SFGM

Pontoise, Hospital Renè Dubois, CIC 961, Dr Morvan, Y Kernéis (7, 0/7)

Reims, Hopital Robert Debré, JC Etienne (12, 0/12) SFGM

Reims, Institute Jean Godinot (onco), Dr Eymard ()*

Rennes, Hôpital Pontchaillou, C Dauriac ()*

Rennes, CHRU, Clinique Médical Infantil, E Le Gall, V Gandemer (7, 2/5)

Rouen, Centre Henri Becquerel, H Tilly, P Lenain (67, 18/49)

Rouen, Hôpital Charles Nicolle, P Tron (17, 7/10)

St Cloud, Centre René Huguenin, M Janvier (5, 0/5)

St Etienne, Hôpital Etienne, D Guyotat, JL Stephan (29, 5/24) SFGM

Strasburg, Hôpital de Hautepierre, B Lioure (74, 16/58)

Strasburg, Hospices Civils, Service de Pédiatrie 5, P Lutz (9, 6/3)

Toulouse, Hôpital de Purpan (hem), CIC 624, M Attal (98, 31/67)

Toulouse, Hôpital de Purpan (peds), A Robert (10, 0/10) SFGM

Toulouse, Centre Claudius Régaud, H Roche, C Chevreau (11, 0/11)

Tours, Hôpital Bretonneau, CIC 272, P Colombat (78, 0/78)

Valenciennes, Hosp De Valenciennes, Dr M Simon ()*

Vandeuvre-les-Nancy, Hôpital d'Enfants, P Bordigoni (50, 33/17)

Vandeuvre-les-Nancy, CHU Nancy-Brabois (hem auto), P Lederlin, F Witz (49, 0/49)

Villejuis, Institut G. Roussy (ads and peds), CIC 503, O Hartmann; CIC 666, JL Pico (119, 23/96)

Villejuif, Hôpital Paul Brousse, B Delmas-Marsalet (9, 0/9)

Georgia: no report

Germany (100 teams; 3637, 1416/2221)

Aachen, Universitätsklinikum RWTH, Med Klinik IV, R Osieka (12, 0/12)

Augsburg, Zentralklinikum, Med Klinik II, G Schlimok (29, 2/27)

Bad Saarow, Humaine Klinikum, G Schultze (40, 2/38)

Berlin, Universitätsklinikum Charité Campus Mitte, II Med Klinik, CIC 807, R Arnold (62, 38/24)

Berlin, Univ Charité der Humboldt Universität Campus, Robert-Rössle Klinik (onco), CIC 518, B Dörken (21, 0/21)

Berlin, Charité Virchow Klinikum (peds), CIC 336, W Ebell (33, 28/5)

Berlin, Charité Virchow Klinikum (ads), CIC 293, W Siegert (76, 29/47)

Berlin, Universitäts-Klinik der FU Benjamin Franklin, CIC 590, W Knauf, E Thiel (32, 10/22)

Bielefeld, Bethel KKS Gilead, U Krümpelmann, FK Lindemann (4, 0/4)

Bielefeld, Franziska Hospital, Prof Weh (8, 0/8)

Bonn, Med Uni Klinik Bonn, T Sauerbruch, I Schmidt-Wolf, R Kleinschmidt (20, 0/20)

Bonn, Universitäts Kinderklinik, U Bode, C Hasan (9, 0/9)

Bremen, CIC 602, ZKK St Jürgen-stasse, C Meier, H Rasch (17, 0/17)

Bremen, DIAKO, DRST 28001, Dr Wolff, KH Pflüger (16, 0/16)

Chemnitz, KH Küchwald, F Fliedler (10, 0/10)

Cottbus, Carl-Thiem Klinikum, Med Klinik II, Ch Rudolf (25, 0/25)

Dortmund, St Johannes Hospital, H Plelken (3, 0/3)

Dresden, Universitätsklinikum Carl Gustav Carus, CIC 808, G Ehninger (150, 92/58)

Duisburg, St Johannes Hospital, CIC 519, M Westerhausen, J Anhuf (22, 0/22)

Duisburg, Klinikum Kalkweg (onco), H Gerhartz (1, 0/1)

Düsseldorf, Heinrich-Heine Universität; Zentrum für Kinderheilkunde, CIC 651, U Gobel, W Nürnberger (25, 18/7)

Düsseldorf, Heinrich-Heine Universität; Medizinische Klinik (haem, onco), CIC 390, C Aul, A Heyll, R Haas (104, 29/75)

Erlangen, Universitäts-Klinik für Kinder und Jugendliche, CIC 809, JD Beck, J Greil (6, 6/0)

Erlangen, Universität Erlangen-Nuremberg, Med Klinikum III, CIC 809, M Gramatzki, W Roesler (30, 9/21)

Eschweiler, St Antonius Hospital, Prof Fuchs (5, 0/5)

Essen, Evangelisches Krankenhaus Essen-Werden GmbH, CIC 784, W Heit (74, 0/74)

Essen, Universitäts-Klinik (hem), G Brittinger, U Dührsen, R Noppeney, J Novotny (11, 0/11)

Essen, West German Cancer Center, S Seeber, A Harstrick, P Bojko (78, 0/78)

Essen, Universitäts-Klinik (ads, peds), CIC 259, UW Schaefer, DW Beelen, V Runde, B Kremens, W Havers, O Basu (146, 130/16)

Frankfurt aM, JW Goethe-Universität (ads, peds), CIC 297, D Hoelzer, H Martin B Kornhuber, D Schwabe (55, 34/21)

Frankfurt, KH Nordwest, A Knuth, E Jäger (4, 0/4)

Freiburg i Br, Universitätsklinik (ads), Med Klinik I, CIC 810, J Finke, W Lange, S Fetscher (130, 69/61)

Freiburg i Br, UniversitätsKinderklinik, CIC 810, C Niemeyer, M Brandis, U Duffiser, B Bächle (20, 16/4)

Göttingen, Georg-August Universität, T Hiddemann, B Wörmann (41, 0/41)

Greifswald, Ernst-Moritz-Arndt Universität (ads + peds), CIC530, G Dölken (26, 8/18)

Gütersloh, Städtkrankenhaus, C Gropp (9, 0/9)

Hagen, Kath Krankenhaus, H Eimermacher, HW Lindemann (8, 0/8)

Halle, Martin Luther Universität, CIC 338 + CIC 654, H-J Schmoll, Dr Wolf, S Burdach (17, 0/17)

Hamburg, Allgemeines Krankenhaus, D Braumann, K Hümmel (13, 0/13)

Hamburg, Eppendorf-Krankenhaus (hem, onco), CIC 673, D Hossfeld (42, 0/42)

Hamburg, Eppendorf-Krankenhaus (KMT) CIC 614, AR Zander (83, 70/13)

Hamburg, KH St George, Dr Lamersdorf, R Kuse (4, 0/4)

Hameln, Kreiskrankenhaus Hameln, H Schmidt (10, 0/10)

Hannover, Medizinische Hochschule, CIC 295, A Ganser, B Hertenstein (66, 32/34)

Hannover, Medizinische Hochschule, Abt Kinderheilkunde, CIC 295, A Reiter, K Welte (26, 19/7)

Hannover, KH Siloah, H Kirchner (16, 0/16)

Heidelberg, Ruprecht-Karls Universitäts-Poliklinik, CIC 524, AD Ho (180, 29/151)

Homburg/Saar, Universität des Saarlandes, CIC 785, L Trümper, M Pfreudschuh (43, 18/25)

Idar-Oberstein, Klinik für Hëmato-/Onkologie, CIC 592, AA Fauser (79, 73/6)

Jena, Klinik fur Innere Medizin II, CIC 533, HG Sayer, K Hoeffken (55, 21/34)

Jena, Universitäts-Kinderklinik, CIC 750, F Zintl, D Fuchs (19, 16/3)

Kaiserslautern, Westpfalzklinikum, F-G Hagmann, H Link, C Wollermann (16, 0/16)

Karlsruhe, Städtisches Klinikum, J Fischer (9, 0/9)

Kassel, Städtische Kliniken, WD Hirschmann, K Schultes (7, 0/7)

Kiel, Christian-Albrechts-Universität (ads, peds), CIC 256, N Schmitz, J Schaub, M Suttorp (89, 22/67)

Köln, Kinderonkologie der Universitäts-Klinik, F Berthold (2, 0/2)

Köln, Universitäts-Klinik, CIC 534, V Diehl, D Söhngen, Ch Scheid (46, 1/45)

Krefeld, Klinikum Krefeld, Med Klinik III, M Planker, R Peceny (8, 0/8)

Leipzig, Universitäts-Klinik, D Niederwieser, W Helbig, R Krahl (107, 73/34)

Lemgo, Klinikum Lippe, HP Lohrmann (11, 0/11)

Lübeck, Städt KH Sud, M Thalheimer, H Bartels (8, 0/8)

Lübeck, Med Universität, T Wagner (19, 0/19)

Lübeck, Klinik für Kinder und Jugendmedizin, P Bucsky, Ch Schultz, K Kruse (2, 0/2)

Magdeburg, Otto-von-Guericke Universität, A Frank, H-G Höffkese (14, 0/14)

Mainz, Medizinische Klinik der Universität, CIC 786, C Huber, K Kolbe, H-G Derigs (97, 43/54)

Mannheim, III Med Klinik, R Hehlmann (7, 0/7)

Marburg, Med Universitätsklinik der Philipps Universität, CIC 645, A Neubauer, R Weide, U Kaiser (45, 15/30)

Minden/Westfallen, Med Klinik, H Bodenstein (19, 0/19)

Mönchengladbach, KH Maria Hilf II, G Trenu, D Kohl, H-E Reis (4, 0/4)

Munich, Städt Krankenhaus Schwabing (peds), L Stengel-Rutkowski (7, 5/2)

Munich, Klinikum Innenstadt, B Emmerich, C Straka (34, 0/34)

Munich, Klinikum Grosshadern (ads) CIC 513, H-J Kolb (157, 107/50)

Munich, Klinikum Grosshadern (peds), CIC 513, C Bender-Götze (9, 6/3)

Munich, Dr v Haunersches Kinderspital (hem and onco) RJ Haas, D Stachel, Dr Schmid (11, 10/1)

Munich, SKH München-Harlaching, R Hartenstein, N Brack (11, 0/11)

München, SKH München-Schwabing, Ch Nerl, N Fischer (21, 0/21)

München, Klinikum rechts der Isar, M Sandherr C Peschel (42, 0/42)

Münster, Westfälische Wilhelms-Universitäts Klinik, Innere Med. CIC 680, W Berdel, J Kienast, Th Büchner, H Ostermann (88, 21/67)

Münster, Westfälische Wilhelms-Universitäts kinderkKlinik (hem and onco), CIC 505, H Jürgens, M Paulussen, J Vormoor (15, 1/14)

Neuss, Lukaskrankenhaus, T Wieberding, P Czygan (4, 0/4)

Nürnberg, Klinikum, CIC 625, H Wandt, K Schäfer-Eckart (40, 12/28)

Offenburg, Klinikum Offenburg, Med Klinik III, B Weber, F Hirsch (0, 0/0)

Oldenburg, Städtische Kliniken, CIC 749, B Metzner (45, 0/45)

Osnabrück, Paracelsus Klinik, OM Koch, G Innig (2, 0/2)

Potsdam, Klinikum Potsdam, A Haas, R Pasold (9, 0/9)

Regensburg, Universitäts Klinikum, CIC 787, E Holler, R Andreesen, A Reichle (105, 38/67)

Rostock, Universitäts Klinikum, CIC 585, M Freund, J Casper (50, 18/32)

Stuttgart, Bürgerhospital, H Benöhr, W Grimminger, D Hahn, (15, 0/15)

Stutttgart, Olgahospital, Pädiatrisches Zentrum, CIC 701, U Gross, J Treuner, E Koscielniak (5, 0/5)

Stuttgart, Diakonissen Krankenhaus, E Heidemann (6, 0/6)

Stuttgart, Robert-Bosch-Krankenhaus, CIC 145, S Martin, W Aulitzky (30, 0/30)

Stuttgart, Katharinenhospital, U Rüther, H Fiechtner, J Schleicher, H-G Mergenthaler (10, 0/10)

Tübingen, Medizinische Universitäts-Klinik, CIC 223, L Kanz, W Brugger, C Faul (123, 59/64)

Tübingen, Medizinische Universitäts-Klinik, Abteilung Pädiatrie, CIC 535, D Niethammer, T Klingebiel (44, 35/9)

Ulm, Medizinische Universitäts-Klinik, CIC 204, D Bunjes (79, 44/35)

Ulm, Kinderklinik der Universität, CIC 204, W Friedrich (47, 45/2)

Wiesbaden, Deutsche Klinik für Diagnostik, CIC 311, R Schwerdtfeger (69, 63/6)

Wiesbaden, Dr Horst-Schmidt Klinikum, CIC 586, N Frickhofen (13, 0/13)

Wuppertal, Klinikum Wuppertal (St Antonius), A Raghavachar (2, 0/2)

Würzburg, Universitätsklinikum, Würzburg, M Wilhelm, K Wilms, M Braun (19, 0/19)

Greece (11 teams; 192, 81/111)

Alexandroupolis, Thrace University Medical School (Haem), G Bourikas (2, 0/2)

Athens, Hellenic Cancer Institute St Savas, CIC 751, A Efremedis, M Stamatellou, K Papanastassiou, M Pouli (40, 5/35)

Athens, ‘Aghia Sophia’ Children's Hospital, CIC 752, S Graphakos (27, 17/10)

Athens, Evanghelismos Hospital, CIC 622, D Karakasis, A Skandalis, N Harhalakis, E Nikiforakis (46, 32/14)

Athens, Diagnosis and Therapy Centre ‘Hygeia’, Maroussi, CIC 643, G Karianakis (12, 4/8)

Athens, Medical Center, CIC 603, A Pigadito, (2, 0/2)

Athens, University of Athens, CIC 604, I Dervenoulas (1, 0/1)

Athens, Laikon General Hospital, CIC 328, Y Rombos, N Stavroyianni, V Kalotychou (10, 0/10)

Crete, University Hospital of Heraklion (peds, hem-onco), CIC 352, M Kalmanti (0, 0/0)

Thessaloniki, The George Papanicolaou General Hospital, CIC 561, AS Fassas (45, 22/23)

Patras, University Medical School, NC Zoumbos, M Tiniakou (7, 1/6)

Hungary (4 teams; 103, 35/68)

Budapest, National Institute of Hematology, CIC 504, K Palocz, R Denes (21, 10/11)

Budapest, Szent Laszlo Hospital, CIC 739, T Masszi, P Reményl, G Kriván (68, 22/46)

Miskolc, Postgraduate Medical School (peds), CIC 599, N Kalman, K Kiss, G Marton (13, 3/10)

Pécs, University of Péfz, CIC 682, H Losonczy (1, 0/1)

Iceland (1 team; 0, 0/0)

Reykjavik, National University Hospital, CIC 605, S Reykdal (0, 0/0) starting in 2000

Iran (1 team; 54, 33/21)

Teheran, Shariati Hospital (Hem-Onco), CIC 633, A Ghavamzadeh (54, 33/21)

Ireland (3 teams; 58, 45/13)

Dublin, St James's Hospital, CIC 257, SR McCann (49, 38/11)

Dublin, St Vincent's Hospital, CIC 541, J Crown ()*

Dublin, Our Lady's Hospital of Sick Children, Crumlin, CIC 774, A O'Meara (9, 7/2)

Israel (5 teams; 363, 150/213)

Haifa, Rambam Medical Center, J Rowe (126, 40/86)

Jerusalem, Hadassah University Hospital, CIC 258, R Or, S Slavin (114, 80/34)

Petach-Tikva, Children's Medical Center, CIC 755, J Stein (33, 15/18)

Revohot, Kaplan Hospital, CIC 327, A Berribi (10, 0/10)

Tel Aviv, University, Chaim Sheba Medical Center (hem) CIC 754, I Ben-Bassat (80, 15/65)

Italy (95 teams; 2918, 810/2108)

Alessandria, SS Antonio e Biagio e C Arrigo, CIC 825, A Levis, A Allione, M Pnin, F Salvi (10, 0/10)

Ancona, Ospedale Toarette, CIC 788, P Leoni, A Olivieri (39, 2/37)

Ancona, Ospedale Toarette (onco), CIC 229, Prof Cellarini (0, 0/0)

Avellino, Giovanni di Guglielmo, CIC 789, E Volpe (16, 0/16)

Avezzano, Ospedale Civile di Avezzano, CIC 921, F Recchia (8, 0/8)

Bari, Policlinico, CIC 649, V Pavone, V Liso (7, 1/6)

Bergamo, Ospedale Riuniti, CIC 658, T Barbui (65, 16/49)

Bologna, St Orsola-Malpighi (haem), CIC 240, G Bandini, G Rosti, S Rizzi (131, 41/90)

Bologna, St Orsola-Malpighi, Oncologia Medica, CIC 657, A Martoni, C Zamagni (14, 0/14)

Bologna, Clinica pediatrica III, CIC 790, A Pession (21, 12/9)

Bolzano, Ospedale S Maurizio, CIC 299, P Coser (38, 2/36)

Brescia, Ospedali Civili, CIC 288, T Izzi (25, 2/23)

Brescia, Università, CIC 741, F Porta (14, 14/0)

Brindisi, Perrino Hospital, CIC 920, G Quarta, S Pinna (5, 0/5)

Cagliari, Ospedale Oncologica, CIC 791, G Broccia, P Dessalvi (45, 9/36)

Cagliari, II Clinica Pediatrica, CIC 820, F Argiolu, A Cao (13, 11/2)

Cagliari, Cattedra di Genetica, University of Cagliari CIC 811, L Contu, G La Nasa (3, 2/1)

Catania, Università, CIC 792, R Giustolisi, G Milone (30, 11/19)***

Cremona, Medicina II, CIC 226, S Morandi (12, 0/12)

Cuneo, Hospital S Croce E Carle (hem), CIC 606, A Gallamini (19, 2/17)

Cuneo, Hospital S Croce E Carle (onco), CIC 355, P Laciura (0, 0/0)

Ferrara, St Anna Hospital, CIC 330, F Lanza, G Castoldi (21, 0/21)

Firenze, Policlinico di Careggi, CIC 304, A Bosi (66, 30/36)

Firenze, Azienda Ospedale, ‘A Meyer’, CIC 600, L Faulkner (14, 0/14)

Forli, Morgagni-Pierantoni Hospital, CIC 298, GL Frassineti, D Amadori (19, 0/19)

Genova, Ospedale S Martino, CIC 217, A Bacigalupo, A Carella, G Santini (143, 73/70)

Genova, Istituto Giannina Gaslini, CIC 274, G Dini (43, 21/22)

Genova, Università, CIC 139, F Patrone (40, 0/40)

Genova, 1st Nat per la Ricercas Cancro, CIC 340, M Venturini (6, 0/6)

Latina, Ospedale S Maria Goretti, A De Blasio (7, 0/7)

Lodi, Ospedale Maggiore Lodi, G Nalli, V Fregoni, (9, 0/9)

Milano, Istituto Scientifico HS Raffaele, CIC 813, C Bordignon (25, 11/14)

Milano, Istituto Nazionale Tumori, CIC 616, A Gianni (49, 0/49)

Milano, Università, CIC 265, G Lambertenghi Deliliers (37, 18/19)

Milano, 1st Nat del Tumore, CIC 381, R Luksch (25, 0/25)

Milano, Ospedale di Niguarda, CIC 294, P Marenco, R Cairoli (35, 11/24)

Milano, Ospedale di Niguarda (hem/oncoST), CIC 294/2, S Siena, P Pedrazzoli, R Schiavo (15, 0/15)

Milano, Istituto Europeo di Oncologia, CIC 331, G Martinelli (113, 0/113)

Milano, Ospedale Fatebenefratelli e Oftalmico (onco), CIC 269, A Scanni, C Bianchi, D Pedretti (5, 0/5)

Milano, 1st Clinico Humanitas (hem-onco), CIC 354, A Santoro, L Castagna (55, 4/51)

Milano, S. Carlo Borromeo Hospital (onco), L Tedeschi (0, 0/0)

Modena, University of Modena, CIC 543, F Narni, A Donelli, R Sabbatini (34, 1/33)

Monza, Ospedale S Gerardo, CIC 279, C Uderzo (30, 20/10)

Monza, Inst Di Scienze Biomediche, CIC 544, P Pioltelli, E Pogliani (39, 11/28)

Napoli, Div. Di Oncologia, CIC 313, C Battista, G Pacilio, B Chiurazzi, G Iodice (18, 0/18)

Napoli, Università, CIC 766, B Rotoli, C Selleri, G De Rosa (31, 13/18)

Napoli, Hospital ‘Pausilipon’ (hem peds), CIC 341, V Poggi, M Ripaldi (3, 1/2)

Napoli, Cardarelli Hospital (hem), CIC 607, F Ferrara (21, 0/21)

Nuoro, Ospedale San Francesco, CIC 793, A Gabbas, A Palmas (12, 0/12)

Orbassano, Ospedale San Luigi Gonzaga, G Saglio (25, 0/25)

Padova, Centro Leucemie Infantili, CIC 285, C Messina, S Cesaro (26, 16/10)

Padova, Centro Oncologia Regionale, CIC 319, S Aversa, S Monfardini (12, 0/12)

Palermo Policlinico (hem), CIC 814, M Mariani (55, 10/45)

Palermo, Ospedale V Cervello, CIC 392, I Majolino, R Scimè, A Cavallaro (72, 23/49)

Palermo, Ospedale ‘La Maddalena’, M Musso, F Porretto, A Crescinanno (0, 0/0)

Parma, Ospedaliera Di Parma (onco), CIC 364, G Cocconi, V Franciosi, G Vasini (0, 0/0)

Parma, Università degli studi, CIC 245, V Rizzoli (24, 4/20)

Pavia, Policlinico S Matteo (hem), CIC 286, C Bernasconi (65, 30/35)

Pavia, Policlinico St Matteo peds), CIC 557, F Locatelli (54, 36/18)

Pavia, Policlinico St Matteo (onco), CIC 562, E Ascari, M Danova (27, 0/27)

Pavia, Fondazione Clinica del Lavoro, CIC 771, A Zambelli, G Robustelli della Cuna (32, 1/31)

Perugia, Silvestrini Hospital, A Amici (3, 1/2)

Perugia, Policlinico Monteluce, Università, CIC 794, MF Martelli, F Aversa (99, 60/39)

Perugia, Policlinico Monteluce, CIC 573, F Grignani (14, 0/14)

Pesaro, Ospedale, CIC 529, G Lucarelli (53, 40/13)

Pescara, Ospedale Civile, CIC 248, P di Bartolomeo (35, 33/2)

Pisa, University of Pisa (Ads hem, peds hem and onco), CIC 795, P Macchia, M Petrini, (34, 15/19)

Pisa, St Chirara Hospital (ads onco) CIC 320, PF Conte, C Bengala (21, 2/19)

Ravenna, Ospedale Civile, CIC 306, G Rosti (49, 0/49)

Reggio di Calabria, Azienda Ospedale ‘Riuniti e Morelli’, CIC 587, P Lacopino (84, 10/74)

Roma, Università S. Eugenio, CIC 756, S Amadori, L Cudillo (41, 15/26)

Roma, Università ‘La Sapienza’, CIC 232, W Arcese, F Mandelli, G Meloni (100, 46/54)

Roma, Università Cattolica, CIC 307, S Cuore, S Sica, G Leone (52, 15/37)

Roma, Ospedale Bambino Gesu, CIC 796, G Deb (17, 0/17)

Roma, Ospedale S. Camillo, CIC 287, A De Laurenzi (39, 7/32)

Roma, Ospedale Bambino Gesu, G De Rossi (12, 7/5)

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (onco), CIC 314, G Lelli (14, 0/14)

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (hem), CIC 526, MM Greco (27, 2/25)

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (peds), CIC 350, P Paolucci (6, 0/6)

Siena, Ospedale Sclavo, CIC 321, F Lauria (27, 0/27)

Taranto, Ospedale Nord, CIC 332, P Mazza, G Palazzo, B Amurri (43, 6/37)

Taranto, Ospedale SS Annunziata, Dr Pezzella (0, 0/0)

Torino, S Giovanni Antica Swde Hospital, M Airoldi (0, 0/0)

Torino, Ospedale Mauriziano Umberto 1, CIC 377, M Aglietta, A Capaldi; G Garetto (18, 0/18)

Torino, University Hospital of Turin, San Giovanni Battista, CIC 231, M Falda, F Locatelli (59, 28/31)

Torino, Dept of Pediatrics, University, CIC 305, E Madon, F Fagioli (28, 8/20)

Trieste, Istituto per l'Infanzia, Clinical Pediatrica, M Andolina, A de Manzini (17, 5/12)

Udine, Policlinico Universitario, CIC 705, M Baccarani, R Fanin, A Geromin (69, 19/50)

Venezia, Ospedale Civile Riuniti de Venezia, CIC 502, T Chisesi, M Vespignani, M Chinello (21, 0/21)

Venice, Civic Hospital (onco), CIC 563, O Vinante, G Azzarello (18, 0/18)

Verbania Pallanza, Ospedale di Verbania, M Bersi (4, 0/4)

Verona Ospedale Civile Maggiore (onco), GL Cetto (4, 0/4)

Verona, Policlinico di Borgo Roma, CIC 623, G Perona (44, 17/27)

Vicenza, Ospedale S Bortolo (hem), CIC 797, R Raimondi, F Rodeghiero (47, 18/29)

Vicenza, Ospedale S Bortolo (onco), CIC 347, V Fosser, P Morandi, P Ruffini (0, 0/0)

Latvia: no report

Liechtenstein: no report

Lithuania: (1 team; 2, 2/0)

Vilnuis, University Hospital (hem), 1 Trociukas (2, 2/0)

Luxemburg (2 teams; 0/42)

Centre Hospitalier, M Dicato (35, 0/35)

Esch-Airette, Hopital de la Ville Esch/Alzette, CIC 545, F Le Moine (7, 0/7)

Macedonia: (1 team 0, 0/0)

Skopje, Medical Faculty (haem), B Georgievski (0, 0/0) starting in 2000

Malta: no report

Moldova: no report

Monaco: no report

Netherlands (14 teams; 601, 257/344)

Amsterdam, Free University Hospital (Haem), CIC 588, GM Ossenkoppele (55, 10/45)

Amsterdam, Free University Hospital (onco), CIC 380, E van der Wall (0, 0/0)

Amsterdam, Academic Medical Center (ads, peds), CIC 247, J van der Lelie, H van den Berg (peds) (29, 6/23)

Amsterdam, The Netherlands Cancer Institute, CIC 976, S Rodenhuis J Baars (25, 0/25)

Groningen, University Hospital (onco),m CIC 395, E de Vries (55, 10/45)

Groningen, University Hospital (hem), CIC 546, E Vellenga (41, 0/41)

The Hague, Leyenburg Hospital, CIC 547, PW Wijermans (7, 0/7)

Leiden, University Medical Centre (ads, peds), CIC 203, J Vossen, R Willemze, (100, 72/27)

Maastricht, University Hospital (haem, onco), CIC 565, HC Schouten, J Wagstaff (33, 15/18)

Nijmegen, University Hospital (ads, peds, onco), CIC 237, A Schattenberg, L Beex, P Hoogerbrugge (77, 44/33)

Rotterdam, Dr Daniel den Hoed Cancer Center, CIC 246, JJ Cornelissen (62, 36/26)

Utrecht, University Hospital (ads and peds), CIC 239, LF Verdonck, NM Wulffraat, D Biesma (93, 64/29)

Zwolle, Isala Klinieken/Sophia Ziekenhuis, CIC 548, M von Marwijk Kooy, (11, 0/11)

Enschede, The Medisch Spectrum Twente, CIC 360, Dr Schaafsma (13, 0/13)

Norway (5 teams; 117, 44/73)

Bergen, Haukelands Sjukhus, P Ernst (8, 0/8)

Oslo, Rikshospitalet, CIC 235, D Albrechtsen, L Brinch (62, 44/18)

Oslo, The Norwegian Radium Hospital, CIC 782, S Kvaloy (21, 0/21)

Oslo, Ullevals Sjukhus (haem), F Wisslöf, J-M Tangen (12, 0/12)

Trondheim, Regionsjukhuset, J Hammerstrom (14, 0/14)

Poland (13 teams; 410, 146/264)

Gdansk, Medical University, CIC 799, A Hellmann (44, 18/26)

Katowice, Silesian Medical Academy, CIC 677, J Holowiecki (124, 31/93)

Krakow, CMUJ, CIC 553, A Skotnicki, (33, 6/27)

Lublin, Ped Hem Onco, CIC 678, J Kowalczyk, (20, 1/19)

Lublin, University Medical School, CIC 695, A Dmoszykska, M Wach, A Walter-Croneck, W Legiec (16, 0/16)**

Poznan, Medical Academy, CIC 730, J Hansz (50, 27/23)

Poznan, Institute of Pediatrics, CIC 641, J Wachowiak (16, 16/0)

Warsaw, Central Clinical Hospital, Military Medical Academy, CIC 816, K Sulek (10, 4/6)

Warsaw, Maria Sklodowska-Curie, Centre of Oncology, CIC 800, J Walewski (23, 1/22)

Warsaw, Inst of Haematology and Blood Transfusion, CIC 693, B Marianska, L Konopka (10, 1/9)

Warsaw, Central Clinical Hospital, CIC 954, W Wiktor-Jedrzejczak, A Dzwigala, M Rokicka-Piotrowicz (10, 1/9)

Wroclaw, University of Medicine, Dept of Children, CIC 817, J Boguslawska-Jaworska (30, 14/16)

Wroclaw, K Diuske Hospital, CIC 538, A Lange (40, 26/14)

Portugal (7 teams; 181, 70/111)

Coimbra, University Hospital, N Costa (18, 0/18)**

Lisbon, Instituto Portugues de Oncologia, CIC 300, M Abecasis, F Leal Costa (59, 20/39)

Lisbon, Hospital de Santa Maria, CIC 636, J Alves do Carmo, F de Lacerda (38, 16/22)

Lisboa, Hospital dos Capuchos, JP Fernandes (20, 0/20)

Porto, Instituto Portugues de Oncologia, CIC 291, P Pimentel, F Campilho (54, 34/20)

Porto, Hospital S Joao (hem), CIC 329, F Principe (8, 0/8)

Porto, Faculty of Medicine of Porto, Hospital S Joao (Onco), CIC 572, JE Guimaraes (2, 0/2)

Romania: ()

Bucharest, Fundeni University Hospital, CIC 296, AD Moicean, D Colita, C Arion ()* new team

Russia (14 teams; 134, 23/11)

Ekaterinburg, City Hospital No. 7, LB Filatov (1, 0/1)

Ekaterinburg, Regional Hospital No. 1, TS Konstantinova, VA Shalaev (5, 0/5)

Moscow, Institute of Biophysics, AE Baranov (11, 3/8)

Moscow, Cancer Research Center, CIC 757, V Ptuschkin (13, 0/13)

Moscow, Cancer Research Center peds Hem/onco, G Mentrevich, (22/ 2/20)

Moscow, Russian Children's Hospital, CIC 694, A Maschan, E Skorobogato, E Pachanov (17, 13/4)**

Moscow, Research Hematology Center of RAS, VG Savtchenko (21, 10/11)

Novosibirsk, Institute of Clinical Immunology, CIC 376, I Lisukov (7, 0/7)

Samara, Regional Hospital, VA Rossiev (13, 5/8)

St Petersburg, Research Institute of Hematology, CIC 724, KM Abdulkadirov (9, 2/7)

St Petersburg, Military Medical Academy, CIC 520, A Novik (4, 0/4)

St Petersburg, Clinical Center for Advanced Medical Tech, CIC 370, E Podoltseva, V Soldatenkov, O Ryasnyanskaya (13, 1/12)

St Petersburg, State Pavlov Medical University, CIC 725, BV Afanassiev, L Zubarovskaya (13, 0/13)

Yaroslavl, City Hospital No 8, VA Lapin (2, 0/2)

San Marino: no report

Slovakia (4 teams; 112, 24/88)

Bansra Bystrica, Roosevelt Hospital, CIC 333, K Mocikova (22, 1/21)

Bratislava, 2nd Children's Clinic, University Hospital, J Lukac (9, 3/6)

Bratislava, University Hospital, CIC 610, M Mistrik (34, 19/15)

Bratislava, National Cancer Institute, CIC 560, J Lakota (47, 1/46)

Slovenia (1 team; 21, 11/10)

Ljublijana, University Medical Centre, CIC 640, J Pretnar (21, 11/10)

Spain (76 teams; 1957, 430/1527)

Alicante, Hospital General, C Rivas-Gonzales (10, 0/10)

Barcelona, Instituto de Oncologia Corachan, D Alfonso-Modolell (11, 0/11)

Barcelona, Santa Creu I Sant Pau (adults), CIC 260, J Sierra, S Brunet (73, 28/45)

Barcelona, Santa Creu I Sant Pau (peds), CIC 260, I Badell Serra, J Cubells-Riero (7, 2/5)

Barcelona, Santa Creu I Sant Pau (onco), CIC 260, Dr JJ Lopez, C Solà (0, 0/49)

Barcelona, Hospital Sant Joan de Deu, CIC 668, J Estella Aguado, (8, 0/8)

Barcelona, Hospital Duran i Reynals (Hem), Institut Catala d'Oncologia, CIC 759, A Granena, C Ferra, J Berlanga (46, 16/30)

Barcelona, Hospital General ‘Vall d'Hebron’, CIC 583, A Julia Font (49, 7/42)

Barcelona, Hospital Mutua de Terrasa (hem-onco), CIC 556, J Marti (8, 0/8)

Barcelona, Hospital Universitario Germans Trias i Pujol, CIC 613, J Ribera (0, 0/0) starting in 2000

Barcelona, Hospital M Infantil, CIC 527, J Ortega (49, 20/29)

Barcelona, Hospital Clinic, CIC 214, E Montserrat, E Carreras (91, 28/63)

Barcelona, Instituto Hematologico Torre Vilana, CIC 777, P Vivancos (7, 0/7)

Barcelona, Instituto Dexeus (hem), CIC 670, A Granena, J Sarra, J Garcia ()*

Cadiz, Hospital del SAS de Jérez, A Leon (53, 0/53)

Cadiz, Hospital Universitario ‘Puerta del mar’, CIC 679, J Gil, (20, 0/20)

Canary Isles, Hospital Insular Las Palmas, CIC 335, F Fernandez-Fuentes, J Gonzalez-San Miguel (8, 0/8)

Canary Isles, Hop, Materno-Infantil Las Palmas (haem, onco), J Lodos Rojas, A Molinés (1, 0/1)

Canary Isles, Hospital Universitario de Canarias, Santa Cruz de Teneriffe, L Hernandez Nieto, MT Hernandez Garcia (11, 0/11)

Canary Isles, Hospital Nostra Senora del Pino, Las Palmas, JJ Malcorra, R Mataix, C Campo ()*

Castellon de La Plana, Hospital general de castellon (haem), R Garcia-Boyero (8, 0/8)

Cordoba, Hospital de la Cruz Roja de Cordoba (haem), J-M Garcia-Castellano (2, 0/2)

Cordoba, Hospital Reina Sofia, CIC 238, A Torres Gomez (61, 30/31)

Cruces-Barakaldo, Hospital de Cruces, I Zuazua-Verde ()*

Galdakao, Hospital de Galdakao, Hem, J Ojanguren, K Atucha (12, 0/12)

Granada, Hospital Virgen de la Nieves, JM de Pablos (37, 9/28)

Jaen, Hospital Cuidad de Jaen (haem), ()*

La Coruna, Complexo Hospitalario Juan Canalejo, FJ Batlle, C Ramirez, P Torres, R Varela (29, 2/27)

Lérida, Hospital Arnan de Villanova, J Macia (9, 0/9)

Lugo, Hospital Xeral-Calde, M Gonzales-Lopez (6, 0/6)**

Madrid, Clinica La Luz, H Cortés-Funes, J Hornedo (10, 0/10)

Madrid, Clinica Moncloa (hem), JM Fernandez, Q Escudero (15, 0/15)

Madrid, Hospital Universitario de Getafe (hem), O Compan, C Monteserin, J Vels, N Somolinos, I Delgado (6, 0/6)

Madrid, Hospital Universitario San Carlos, CIC 733, J Diaz Mediavilla, L Llorente (16, 0/16)

Madrid, Hospital Univ San Carlos, CIC 733, M Martin, E Diaz-Rubio, A Casado, JA Lopez-Martin (21, 0/21)

Madrid, Hospital Ruber Internacional, J Diaz Mediavilla (2, 0/2)

Madrid, Unidad de TMO-ONC 4, Hospital Gregorio Maranon, CIC 819, JL Diez Martin (34, 7/27)

Madrid, Clinica Ruber, JM Fernandez-Ranada, Q Escudero (15, 0/15)

Madrid, Hospital de la Princesa, CIC 236, JM Fernández Rañada, A Figuera, A Alegre (67, 31/36)

Madrid, Clinica Puerta de Hierro, CIC 728, MN Fernandez (32, 17/15)

Madrid, Hospital General La Paz (ads), F Hernandez Navarro, E Ojeda (47, 10/37)

Madrid, Hospital Doce de Octubre, JJ Lahuerta (hem), H Cortés Funes (onco), J Lopez Perez (peds) (67, 7/60)

Madrid, Hospital Nino Jesus, LM Madero (29, 14/15)

Madrid, Hospital La Paz Infantil, CIC 734, A Martinez-Rubio, A Sastre, P Garcia-Miguel (18, 7/11)

Madrid, Hospital Ramon y Cajal (peds) A Munoz Villa, MS Maldonado (12, 6/6)

Madrid, Hospital Ramon y Cajal (ads), CIC 615, J Odriozola, J Pérez de Oteyza, J Lopez, J Garcia Larana (36, 12/24)

Madrid, Fundacion Jiminez Diaz, J Tomas, C Paniagua, F Lobo (15, 5/10)

Madrid, Hospital Militar Gomez Ulla, F Sancho-Cuesta, S Enrech-Frances (7, 0/7)

Malaga, Hospital Regional, CIC 576, J Maldonado (44, 23/21)

Murcia, Hospital Virgen de la Arrivxaca, CIC 323, R Candel Parra (23, 0/23)

Murcia, Hospital General, CIC 735, JM Moraleda, V Vicente-Garcia, I Heras (29, 10/19)

Orense, Hospital Cristal-Pinor (hem), J-L Sastre-Moral, M Vazquez (16, 0/16)

Oviedo, Hospital Covadonga, CIC 642, D Carrera Fernandez, C Rodriguez Pinto (23, 4/19)

Palma de Mallorca, Hospital Son Dureta, CIC 722, J Besalduch, HS Dureta (21, 3/18)

Palma de Mallorca, Policlinica Miramar, J Besalduch, A Sampol (8, 0/8)

Pamplona, Hospital Provincial de Navarra, CIC 577, E Pérez Equiza, MJ Uriz Pascual, J Gastearena (23, 0/23)

Pamplona, Clinica Universitario de Navarra, CIC 737, J Rifon (19, 4/15)

Pontevedra, Hospital Montecelo, CIC 549, M Constela (18, 0/18)

Salamanca, Complejo Hospital, CIC 727, D Caballero (86, 24/63)

San Sebastian, Hospital Nostra Senora de Aranzazu, CIC 598, J Marin, D Martinez (38, 6/32)

Santander, Hospital Universitario M de Valdecilla, CIC 242, A Iriondo, E Conde, E Bureo, A Zubizarreta-Pina (69, 22/47)

Sant Cugat des Vallés, Hospital General de Cataluna, M Sureda-Gonzales (10, 0/10)**

Santiago de Compostela, Hospital Xeral de Galicia, CIC 570, JL Bello (18, 5/13)

Sevilla, Hospital Universitario Virgen del Rocio, CIC 769, JM Rodriguez Fernandez (56, 21/35)

Sevilla, Clinica Del Sagrado Corazon, M Rodrigues ()*

Tarragona, Hospital de Tarragona Joan XXIII (hem), C Alonso y Macia, (3, 0/3)

Valencia, Hospital Universitario La Fe (peds), CIC 653, V Castel, A Verdeguer (18, 3/15)

Valencia, Hospital Clinico Universitario, CIC 282, J Garcia-Conde, C Solano (88, 13/75)

Valencia, Instituto Valenciano de Oncologia, V Guillen, J Palau (35, 0/35)

Valencia, Hospital Universitario La Fe, CIC 663, MA Sanz, GF Sanz (64, 27/37)

Valencia, Clinica Virgen del Consuelo (hem), MA Sanz ()*

Valencia, Hospital Doctor Peset (hem), P Ribas Garcia (16, 0/16)

Valladolid, Hospital Rio Hortega, J Garcia Frade (20, 0/20)

Vigo, Hospital Xeral-Cies, A Martinez-Dalmau (30, 4/26)

Zaragoza, Hospital Miguel Servet (hem and onco) M Girald, G Pérez-Lugmus, D Rubio-Félix, A Anton (37, 3/34)

Zaragoza, Clinico Universitario Lozano Blesa (Haem, onco), A Tres, P Palomera, M Gutierrez, J Mayordomo, (47, 0/47)

Sweden (10 teams; 422, 150/272)

Goteborg, Medical Clinic, CIC 715, M Brune (70, 17/53)

Goteborg, East Hospital, CIC 289, A Fasth, S Rodjer (12, 4/8)

Huddinge, Hospital, CIC 212, P Ljungman (85, 54/31)

Linköping, University Hospital, CIC 740, G Juliusson (47, 20/27)

Lund, University Hospital, CIC 283, AN Bekassy (56, 16/40)

Malmö, University Hospital, I Turesson (5, 0/5)

Örebro, Medical Center Hospital, CIC 738, U Tidefelt (11, 0/11)

Stockholm, Karolinska Hospital, CIC 626, M Björkholm (20, 0/20)

Umea, Norrland University Hospital, CIC 731, A Wahlin, P Hörnsten, J Lindh, L Eliasson (33, 8/25)

Uppsala, University Hospital, CIC 266, B Simonsson, K Carlson, H Hagberg (83, 31/52)

Switzerland (12 teams; 277, 80/197)

Aarau, Kantonsspital, CIC 316, M Wernli (15, 0/15)

Basel, Kantonsspital, CIC 202, A Gratwohl, T Kühne, R Herrmann (57, 35/22)

Bellinzona, Ospedale San Giovanni, CIC 829, F Cavalli, M Ghielmini (7, 0/7)

Berne, Inselspital, CIC 221, A Tobler, K Leibundgut (27, 0/27)

Geneva, Hôpital cantonal universitaire, CIC 261, B Chapuis, J Humbert (27, 23/4)

Geneva, Clinique La Tour, C Irlé (9, 0/9)

Lausanne, CHUV, CIC 810+ CIC 579, D Schapira, T Kovacsovics, N Nenadov-Beck (50, 0/50)

Neuchatel, Hopital des Cadolles, D Piguet (2, 0/2)

Pully, Clinic de la Source, W von Fliedner (1, 0/1)

St Gallen, Kantonsspital, CIC 324, U Hess (11, 0/11)

Zurich, University Hospital, CIC 208, J Gmür, R Stahel, L Jost, R Seger (64, 22/42)

Zurich, Klinik Im Park, J Gmür, U Breitenstein, A von Rohr (7, 0/7)

Turkey (21 teams; 328, 143/185)

Ankara, Numune Education and Research Hospital, CIC 691, T Demirer (32, 10/22)

Ankara, Ibn-1 Sina Hospital, CIC 617, H Koc (62, 42/20)

Ankara Hacettepe University, Inst of Oncology Hematopoietic Stem Cell Transplantation Unit CIC 292, E Kansu (2, 2/0)

Ankara, Childrens Hospital, Hacettepe University, A Tuncer, D Uckan (14, 14/0)

Ankara, University of Ankara (peds), CIC 620, E Unal (5, 5/0)

Ankara-Etlik, GATA BMT Center, CIC 372, A Yalcin, F Arpaci, A Özet, C Beyan, A Ural (53, 19/34)

Antalya, Akdeniz University Hospital, CIC 618, MA Yesilipek, V Hazar, O Yegin (9, 4/5)

Antalya, Akdeniz University Hospital, CIC 685, L Undar (7, 3/4)

Balcali, Hospital, CIC 821, A Tanyeli (3, 1/2)

Eskisehir, Osmangazi University, CIC 686, Z Güblas (2, 1/1)

Istanbul, Marmara University, Altunizade, CIC 714, S Ratip, T Akoglu (6, 4/2)

Istanbul, Maltepe Medical Faculty, CIC 210, K Ozerkan, A Tamkan (0, 0/0,) new team for 2000

Istanbul, Cerrahpasa Medical School, CIC 761, B Ferhanoglu, T Soysal, Z Baslar (13, 6/7)

Istanbul, Tip Fakultesi, CIC 762, G Gedikoglu (21, 17/4)

Istanbul, Medical Faculty, CIC 760, T Yangün (18, 9/9)

Istanbul, GATA Haydarpasa Egitim Hst, CIC 687, N Uskent (21, 0/21)

Istanbul, Institute of Oncology, CIC 689, H Onat (3, 0/3)

Izmir, Ege University Medical Faculty (ads), CIC 628, S Cagirgan (42, 3/39)

Izmir, Ege University Medical Faculty (peds), CIC 621, S Kansoy (5, 2/3)

Izmir, Dokuz Eylul University, CIC 688, U Yilmaz ()*

Kayseri, Erciyes University Hospital, CIC 627, A Unal, M Cetin, (10, 1/9)

Ukraine: no report

United Kingdom (55 teams; 2084, 760/1324)

Aberdeen, The Royal Infirmary, CIC 344, DJ Culligan (17, 1/16)

Bangor, Gwynedd Hospital, CIC 736, H Parry (11, 0/11)

Bath, Royal United Hospital, CIC 619, JG Smith (9, 0/9)

Belfast, Belvoir Park Hospital, P Abram (5, 0/5)

Belfast, Royal Victoria Hospital, CIC 268, F Jones, MF McMullin, P Burnside (20, 15/5)

Belfast City Hospital, CIC 753, TCM Morris, L Ranaghan (17, 0/17)

Birmingham, The Birmingham Childrens Hospital, CIC 781, PJ Darbyshire, MW Williams (25, 25/0)

Birmingham, Queen Elizabeth Hospital, CIC 387, P Mahendra, C Craddock (67, 26/41)

Birmingham, Heartlands Hospital, CIC 284, DW Milligan (52, 23/29)

Bournemouth, Royal Bournemouth Hospital, CIC 765, H Mying (21, 0/21)

Bristol, Royal Hospital for Sick Children, CIC 386, JM Cornish and Southmead Hospital, J Hows, MG Rainey (93, 66/27)

Cambridge, Addenbrooke's Hospital and Norwich Hospital, CIC 566 + 391, RE Marcus, M Deans (58, 17/41)

Cardiff, University of Wales, CIC 303, CH Poynton (41, 9/32)

Coventry, Walsgrave Hospital, R Harris (8, 0/8)**

Dundee, Ninewells Hospital, CIC 719, D Bowen (7, 0/7)

Edinburgh, Western General Hospital, (hem) CIC 228, PS Ganly, MJ Mackie, PRE Johnson (36, 14/22)

Edinburgh, Western General Hospital (onco) CIC 228, R Leonard (0, 0/0 new team for 2000)

Exeter, Royal Devon and Exeter Hospital, CIC 571, M Joyner (4, 0/4)

Glasgow, Royal Infirmary, CIC 244, A Parker, IG McQuaker (36, 12/24)

Glasgow, The Western Infirmary, CIC 325, T Fitzsimons (25, 0/25)

Glasgow, Royal Hospital for Sick Children, CIC 707, Dr Gibson (14, 10/4)

Leeds, St James's University Hospital and The General Infirmary, D Barnard, S Kinsey, JA Child, CIC 154 (100, 32/68)

Leicester, Royal Infirmary, CIC 713, AE Hunter (36, 13/23)

Liverpool, Royal Liverpool University Hospital, CIC 501, RE Clark (70, 12/58)

Liverpool, Alder Hay, (6, 5/1)

London, Hammersmith and Charing Cross Hospital, CIC 205 & CIC 510, JM Goldman, D Samson, E Kanfer (120, 59/61)

London, University College Hospital, CIC 224, AH Goldstone (158, 59/99)

London Oncology Marrow Transplantation Group, CIC 263, PJ Gravett (15, 1/14)

London, St George's Hospital, CIC 539, J Marsh, S Ball, EC Gordon-Smith (19, 7/12)

London, King's College, CIC 763, A Pagliuca, GJ Mufti (45, 22/23)

London, Royal Marsden Hospital, CIC 218, R Powles, J Mehta (161, 37/124)

London, Royal Free Hospital, CIC 216, HG Prentice, M Potter (63, 46/17)

London, St Bartholomew's, CIC 768 and the Royal London Hospital, CIC 269, A Rohatiner, AC Newland (61, 22/39)

London, Guy's Hospital, CIC 721, S Schey (38, 4/34)

London, Institute of Child Health, CIC 243, P Veys, IM Hann (45, 39/6)

Manchester, Christie Hospital, G Morgenstern (107, 15/92)

Manchester, Royal Children's Hospital, CIC 521, AM Will (33, 24/9)

Manchester, The Royal Infirmary, JA Yin (39, 20/19)

Manchester, Trafford General Hospital, PA Carrington (4, 0/4)

Manchester, Hope Hospital, PA Carrington (1, 0/1)

Newcastle upon Tyne, Royal Victoria Infirmary, CIC 276, GH Jackson, SJ Proctor, P Taylor, A Cant, R Skinner (72, 31/41)

Norwich, Norfolk and Norwich Hospital (hem), CIC 391, M Deane (transplants performed in 1999 at Norwich are reported through Addenbrookes)

Nottingham, City Hospital, CIC 717, N Russell (93, 52/41)

Oxford, John Radcliffe Hospital, Headington, CIC 255, TJ Littlewood, C Bunch, C Mitchell, C Hatton, G Hall, J Wainscoat (40, 13/27)

Plymouth, Derriford Hospital, CIC 823, MD Hamon (28, 5/23)

Poole, Dorset Cancer Centre, CIC 580, A Bell (16, 0/16)

Rotherham, General Hospital, CIC 647, H Barker (4, 0/4)

Sheffield, The Royal Hallamshire and Weston Park Hospitals (ads, peds, onco) CIC 778, E Vandenberghe, A Vora, P Lorigan (57, 21/36)

Somerset, Taunton and Somerset Hospital, SA Johnson, S Rule (7, 0/7)

CRC Wessex, Southampton, CIC 704, A Smith, A Duncombe, J Sweetenham, J Kohler (58, 3/55)

Stoke-on-Trent, North Staffordshire Royal Infirmary, R Chasty (8, 0/8)

Sunderland, The Sunderland Royal, PJ Carey (1, 0/1)

Swansea, Singleton Hospital, Sketty, S Al Ismail (9, 0/9)

Swindon, Princess Margaret Hospital (Hem), CIC608, NE Blesing, A Gray, S Green, A Koster (4, 0/4)

Wakefield, Pinderfield's General Hospital, CIC 764, MC Galvin, D Wright (8, 0/8)

Yugoslavia (Serbia and Montenegro) (4 teams: 32, 6/26)

Belgrade, Clinical Centre of Serbia, CIC 373, M Colovic, A Bogdanovic (3, 0/3)

Belgrade, Mother and Child Health Institute, D Makic (2, 0/2)

Belgrade, Military Medical Academy, CIC 582, M Malesevic (26, 5/21)

Novi Sad, Institute of Internal Diseases, CIC 655, D Pejin (1, 0/1)

* no report

** late data, not included in Tables and Figures

*** late correction, appendix only, not included in Tables and Figures

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Gratwohl, A., Passweg, J., Baldomero, H. et al. Hematopoietic stem cell transplantation activity in Europe 1999. Bone Marrow Transplant 27, 899–916 (2001). https://doi.org/10.1038/sj.bmt.1702995

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