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| Case reports |
| Plasmodium vivax causing pancytopenia after allogeneic blood stem cell transplantation in CML |
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| V Raina1,a, A Sharma1, S Gujral2 and R Kumar2 |
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1Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
2Department of Laboratory Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
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aCorrespondence: Dr V Raina, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, 110 029, India |
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| Abstract |
| A 20-year-old male patient with chronic myeloid leukemia (CML), in chronic phase, underwent allogeneic blood stem cell transplantation in August 1996. Engraftment was well documented in the marrow on day 19, but pancytopenia and mild splenomegaly continued. On day +70, the patient developed severe anemia and had one pyrexial episode. He was detected to have malaria (Plasmodium vivax). After chloroquin therapy, the pancytopenia reversed completely. We suggest that malaria should be considered as a possible cause of pancytopenia in the post-transplant period in endemic areas. |
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| Keywords |
| allogeneic blood stem cell transplantation; CML; malaria; pancytopenia |
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| Received 30 September 1997; accepted 1 March 1998 |
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| July 1998, Volume 22, Number 2, Pages 205-206 |
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