ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
July 14 2008 |
July 7 2008 |
June 30 2008 |
June 23 2008 |
June 16 2008 |
June 9 2008 |
June 2 2008 |
May 26 2008 |
May 19 2008 |
April 21 2008
July 21 2008
Commentary
Atypical pharmacologies at 
-adrenoceptors FREE
R J Summers
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.293
Reviews
Annexin-A1: a pivotal regulator of the innate and adaptive immune systems
F D'Acquisto, M Perretti and R J Flower
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.252
Mechanisms of oxygen sensing: a key to therapy of pulmonary hypertension and patent ductus arteriosus
E K Weir, M Obreztchikova, A Vargese, J A Cabrera, D A Peterson and Z Hong
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.291
Research Papers
Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice
V Brancaleone, F Roviezzo, V Vellecco, L De Gruttola, M Bucci and G Cirino
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.296
Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone
H J Leis and W Windischhofer
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.304
Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy
J Reutenauer, O M Dorchies, O Patthey-Vuadens, G Vuagniaux and U T Ruegg
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.285
1-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats
A A Scopinho, L B M Resstel and F M A Corrêa
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.295
YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway
S Y Wu, S L Pan, T H Chen, C H Liao, D Y Huang, J H Guh, Y L Chang, S C Kuo, F Y Lee and C M Teng
Br J Pharmacol advance online publication, July 21, 2008; doi:10.1038/bjp.2008.292
July 14 2008
Research Papers
Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between 
-opioid and cannabinoid CB1 receptors
R Capasso, F Borrelli, M G Cascio, G Aviello, K Huben, J K Zjawiony, P Marini, B Romano, V Di Marzo, F Capasso and A A Izzo
Br J Pharmacol advance online publication, July 14, 2008; doi:10.1038/bjp.2008.294
Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat
B Marcos, T T Chuang, F J Gil-Bea and M J Ramirez
Br J Pharmacol advance online publication, July 14, 2008; doi:10.1038/bjp.2008.281
Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide
R Rodriguez-Rodriguez, E Stankevicius, M D Herrera, L Østergaard, M R Andersen, V Ruiz-Gutierrez and U Simonsen
Br J Pharmacol advance online publication, July 14, 2008; doi:10.1038/bjp.2008.289
July 7 2008
Commentary
Targeting airway inflammation: PMX464 and the epithelial bulls eye FREE
D W Sexton
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.290
Reviews
Novel long-acting bronchodilators for COPD and asthma
M Cazzola and M G Matera
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.284
Principles of Safety Pharmacology
M K Pugsley, S Authier and M J Curtis
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.280
Literature-based evaluation of four 'hard endpoint' models for assessing drug-induced torsades de pointes liability
M A Vos
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.277
Research Papers
Estimating the efficiency of benzodiazepines on GABAA receptors comprising 
1 or 2 subunits BJPOpen
I Baburin, S Khom, E Timin, A Hohaus, W Sieghart and S Hering
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.271
Bradykinin regulates human colonic ion transport in vitro
A W Baird, M M Skelly, D P O'Donoghue, K E Barrett and S J Keely
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.288
2-Adrenoceptor action on cell proliferation and mammary tumour growth in mice
A Bruzzone, C Pérez Piñero, L F Castillo, M G Sarappa, P Rojas, C Lanari and I A Lüthy
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.278
The cardiovascular and pharmacokinetic profile of dofetilide in conscious telemetered beagle dogs and cynomolgus monkeys
T M Haushalter, G S Friedrichs, D L Reynolds, M Barecki-Roach, G Pastino, R Hayes and A S Bass
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.275
Dietary trace amine-dependent vasoconstriction in porcine coronary artery
A A Herbert, E J Kidd and K J Broadley
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.286
Smooth muscle 1D-adrenoceptors mediate phenylephrine-induced vasoconstriction and increases in endothelial cell Ca2+ in hamster cremaster arterioles
W F Jackson, E M Boerman, E J Lange, S S Lundback and K D Cohen
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.276
Investigation of the role of 5-HT2 receptor subtypes in the control of the bladder and the urethra in the anaesthetized female rat
Y Mbaki and A G Ramage
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.273
Production of a specific extracellular inhibitor of TRPM3 channels
J Naylor, C J Milligan, F Zeng, C Jones and D J Beech
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.283
Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues
K M Waldhauser, K Brecht, S Hebeisen, H R Ha, D Konrad, D Bur and S Krähenbühl
Br J Pharmacol advance online publication, July 7, 2008; doi:10.1038/bjp.2008.287
June 30 2008
Commentary
Cancer and the blood–brain barrier: 'Trojan horses' for courses? FREE
M Mazza, I F Uchegbu and A G Schätzlein
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.274
Research Papers
Pharmacological profiling of neuropeptides on rabbit vaginal wall and vaginal artery smooth muscle in vitro
K L Aughton, K Hamilton-Smith, J Gupta, J S Morton, C P Wayman and V M Jackson
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.253
Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues
D J Behm, J J McAtee, J W Dodson, M J Neeb, H E Fries, C A Evans, R R Hernandez, K D Hoffman, S M Harrison, J M Lai, C Wu, N V Aiyar, E H Ohlstein and S A Douglas
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.266
PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-B-dependent proinflammatory activation of alveolar epithelial cells BJPOpen
M E Callister, L Pinhu, M C Catley, A D Westwell, R Newton, S K Leaver, G J Quinlan, T W Evans, M J Griffiths and A Burke-Gaffney
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.258
Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation
R Colucci, C Blandizzi, N Ghisu, T Florio and M Del Tacca
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.268
Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase
M Oppermann, V T-V Dao, T Suvorava, M Bas and G Kojda
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.269
Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms
L Xia, X X Wang, X S Hu, X G Guo, Y P Shang, H J Chen, C L Zeng, F R Zhang and J Z Chen
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.272
Predicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea-pig model BJPOpen
X Yao, D L Anderson, S A Ross, D G Lang, B Z Desai, D C Cooper, P Wheelan, M S McIntyre, M L Bergquist, K I MacKenzie, J D Becherer and M A Hashim
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.267
Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice
A Zarbock, M Allegretti and K Ley
Br J Pharmacol advance online publication, June 30, 2008; doi:10.1038/bjp.2008.270
June 23 2008
Commentaries
The 1L-adrenoceptor is an alternative phenotype of the 1A-adrenoceptor FREE
C P Nelson
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.264
Epigenetic biomarkers in psychiatric disorders FREE
J Peedicayil
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.254
Reviews
Moving towards better predictors of drug-induced torsades de pointes
A S Bass, B Darpo, J-P Valentin, P Sager and K Thomas
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.215
The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles
B Mayer and M Beretta
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.263
Research Papers
High-affinity blockade of voltage-operated skeletal muscle and neuronal sodium channels by halogenated propofol analogues
G Haeseler, M Karst, N Foadi, S Gudehus, A Roeder, H Hecker, R Dengler and M Leuwer
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.255
Hypertension and the absence of EDHF-mediated responses favour endothelium-dependent contractions in renal arteries of the rat
F S Michel, G S Man, R Y K Man and P M Vanhoutte
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.256
Effects of pregabalin on visceral pain responses and colonic compliance in rats
A Ravnefjord, M Brusberg, H Larsson, E Lindström and V Martínez
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.259
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2
A Régina, M Demeule, C Ché, I Lavallée, J Poirier, R Gabathuler, R Béliveau and J-P Castaigne
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.260
The 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels
Q Tang, Z-Q Li, W Li, J Guo, H-Y Sun, X-H Zhang, C-P Lau, H-F Tse, S Zhang and G-R Li
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.261
PEGylated cholecystokinin is more potent in inducing anorexia than conditioned taste aversion in rats
I Verbaeys, F León-Tamariz, H Pottel, E Decuypere, Q Swennen and M Cokelaere
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.257
Raloxifene protects endothelial cell function against oxidative stress
C M Wong, L M Yung, F P Leung, S-Y Tsang, C L Au, Z-Y Chen, X Yao, C H K Cheng, C-W Lau, M Gollasch and Y Huang
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.262
The effect of changes in core body temperature on the QT interval in beagle dogs: a previously ignored phenomenon, with a method for correction BJPOpen
H J van der Linde, B Van Deuren, A Teisman, R Towart and D J Gallacher
Br J Pharmacol advance online publication, June 23, 2008; doi:10.1038/bjp.2008.265
June 16 2008
Commentary
Brivaracetam: a rational drug discovery success story FREE
M A Rogawski
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.221
Reviews
Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery
T P Barros, W K Alderton, H M Reynolds, A G Roach and S Berghmans
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.249
Arachidonic acid and ion channels: an update
H Meves
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.216
Cellular basis of drug-induced torsades de pointes
D M Roden
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.238
Sensitive and reliable proarrhythmia in vivo animal models for predicting drug-induced torsades de pointes in patients with remodelled hearts
A Sugiyama
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.240
Research Papers
Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells BJPOpen
A Banerjee, G Damera, R Bhandare, S Gu, Y S Lopez-Boado, R A Panettieri Jr and O Tliba
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.232
Mechanisms of augmented vasoconstriction induced by 5-hydroxytryptamine in aortic rings from spontaneously hypertensive rats
K Budzyn, R M Ravi, A A Miller and C G Sobey
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.247
Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5
D De Filippis, A Russo, A D'Amico, G Esposito, P Concetta, M Cinelli, G Russo and T Iuvone
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.211
Low concentrations of tetrodotoxin interact with tetrodotoxin-resistant voltage-gated sodium channels
C E Farmer, K J Smith and R J Docherty
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.235
The 1A-adrenoceptor gene is required for the 1L-adrenoceptor-mediated response in isolated preparations of the mouse prostate
K T Gray, J L Short and S Ventura
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.245
Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors
J Gupta, R J Russell, C P Wayman, D Hurley and V M Jackson
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.226
Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures
C-Y Hsiang and T-Y Ho
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.242
Interactions between CB1 receptors and TRPV1 channels mediated by 12-HPETE are cytotoxic to mesencephalic dopaminergic neurons
S R Kim, E Bok, Y C Chung, E S Chung and B K Jin
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.246
Prediction of clinical response based on pharmacokinetic/pharmacodynamic models of 5-hydroxytryptamine reuptake inhibitors in mice
M Kreilgaard, D G Smith, L T Brennum and C Sánchez
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.243
Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and 2-adrenoceptor mechanisms
R A Ngala, J O'Dowd, S J Wang, A Agarwal, C Stocker, M A Cawthorne and J R S Arch
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.244
Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids
L Thors, M Belghiti and C J Fowler
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.237
A dose escalation study in sheep of the effects of the benzodiazepine CNS 7056 on sedation, the EEG and the respiratory and cardiovascular systems
R N Upton, A M Martinez and C Grant
Br J Pharmacol advance online publication, June 16, 2008; doi:10.1038/bjp.2008.228
June 9 2008
Commentary
The failure of torcetrapib: what have we learned? FREE
T R Joy and R A Hegele
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.248
Reviews
Pulmonary hypertension: therapeutic targets within the serotonin system
Y Dempsie and M R MacLean
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.241
On the fitting of binding data when receptor dimerization is suspected
J Giraldo
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.234
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
M Oka, K A Fagan, P L Jones and I F McMurtry
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.239
Key clinical considerations for demonstrating the utility of preclinical models to predict clinical drug-induced torsades de pointes
P T Sager
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.222
Research Papers
The PKs PKA and ERK 1/2 are involved in phosphorylation of TH at Serine 40 and 31 during morphine withdrawal in rat hearts
P Almela, M V Milanés and M L Laorden
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.224
Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB1 receptor
B Bosier, E Hermans and D M Lambert
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.230
Anti-inflammatory actions of aprotinin provide dose-dependent cardioprotection from reperfusion injury
J M Carter, U Buerke, E Rössner, M Russ, S Schubert, H Schmidt, H Ebelt, D Pruefer, A Schlitt, K Werdan and M Buerke
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.223
Pathology-specific effects of the I Kur/I to/I K,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation
T Christ, E Wettwer, N Voigt, O Hála, S Radicke, K Matschke, A Várro, D Dobrev and U Ravens
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.209
Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone BJPOpen
M J Forrest, D Bloomfield, R J Briscoe, P N Brown, A-M Cumiskey, J Ehrhart, J C Hershey, W J Keller, X Ma, H E McPherson, E Messina, L B Peterson, W Sharif-Rodriguez, P K S Siegl, P J Sinclair, C P Sparrow, A S Stevenson, S-Y Sun, C Tsai, H Vargas, M Walker III, S H West, V White and R F Woltmann
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.229
Blockade of adenosine A2B receptors ameliorates murine colitis BJPOpen
V L Kolachala, B K Ruble, M Vijay-Kumar, L Wang, S Mwangi, H E Figler, R A Figler, S Srinivasan, A T Gewirtz, J Linden, D Merlin and S V Sitaraman
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.227
Hypercholesterolaemia exacerbates ventricular remodelling after myocardial infarction in the rat: role of angiotensin II type 1 receptors
M M
czewski, J Mczewska and M Duda
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.218
CO-MP4, a polyethylene glycol-conjugated haemoglobin derivative and carbon monoxide carrier that reduces myocardial infarct size in rats
K D Vandegriff, M A Young, J Lohman, A Bellelli, M Samaja, A Malavalli and R M Winslow
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.219
Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents
S Y M Yeung, M Schwake, V Pucovský and I A Greenwood
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.231
Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice
S Y 
nan and K Büyükaf
ar
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.225
Anthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone
T 
im
nek, M t
rba, O Popelová, H Kaiserová, M Adamcová, M Hroch, P Ha
ková, P Po
ka and V Gerl
Br J Pharmacol advance online publication, June 9, 2008; doi:10.1038/bjp.2008.236
June 2 2008
Reviews
Gaddum and LSD: the birth and growth of experimental and clinical neuropharmacology research on 5-HT in the UK
A R Green
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.207
In vitro models of proarrhythmia
C L Lawrence, C E Pollard, T G Hammond and J-P Valentin
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.195
Research Papers
Isolated porcine bronchi provide a reliable model for development of bronchodilator anti-muscarinic agents for human use
G D'Agostino, A M Condino, L Gioglio, F Zonta, M Tonini and A Barbieri
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.208
Vasorelaxation induced by prostaglandin E2 in human pulmonary vein: role of the EP4 receptor subtype
N Foudi, L Kotelevets, L Louedec, G Leséche, D Henin, E Chastre and X Norel
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.214
Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein
J Gierten, E Ficker, R Bloehs, K Schlömer, S Kathöfer, E Scholz, E Zitron, C Kiesecker, A Bauer, R Becker, H A Katus, C A Karle and D Thomas
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.213
Dose–response effects of sotalol on cardiovascular function in conscious, freely moving cynomolgus monkeys
J J Lynch III, A W Wilson, L E Hernandez, R A Nelson, K C Marsh, B F Cox and S W Mittelstadt
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.206
Characterization of the 1-adrenoceptor subtype mediating contractions of the pig internal anal sphincter
K A Mills, N Hausman and R Chess-Williams
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.217
Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects
M I Mohammed Abdul, X Jiang, K M Williams, R O Day, B D Roufogalis, W S Liauw, H Xu and A J McLachlan
Br J Pharmacol advance online publication, June 2, 2008; doi:10.1038/bjp.2008.210
May 26 2008
Reviews
Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders
B M Jensen, C Akin and A M Gilfillan
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.204
Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective
C E Pollard, J-P Valentin and T G Hammond
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.203
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
I Wessler and C J Kirkpatrick
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.185
Research Papers
Regional haemodynamic responses to adenosine receptor activation vary across time following lipopolysaccharide treatment in conscious rats BJPOpen
L Jolly, J E March, P A Kemp, T Bennett and S M Gardiner
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.205
Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A
A Matagne, D-G Margineanu, B Kenda, P Michel and H Klitgaard
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.198
Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres
K Sakamoto, H Mikami and J Kimura
Br J Pharmacol advance online publication, May 26, 2008; doi:10.1038/bjp.2008.192
May 19 2008
Research Papers
Predicting drug-induced changes in QT interval and arrhythmias: QT-shortening drugs point to gaps in the ICHS7B Guidelines BJPOpen
H R Lu, E Vlaminckx, A N Hermans, J Rohrbacher, K Van Ammel, R Towart, M Pugsley and D J Gallacher
Br J Pharmacol advance online publication, May 19, 2008; doi:10.1038/bjp.2008.191
Adrenaline reveals the torsadogenic effect of combined blockade of potassium channels in anaesthetized guinea pigs
G Michael, K A Kane and S J Coker
Br J Pharmacol advance online publication, May 19, 2008; doi:10.1038/bjp.2008.169
Retraction: Sex differences in the expression of sodium/calcium exchanger influence the arrhythmia phenotype in the long QT syndrome type 2
G Salama, B London, L J Kerchner, N R Salama and T Liu
Br J Pharmacol advance online publication, May 19, 2008; doi:10.1038/bjp.2008.183
