TABLE OF CONTENTS
Volume 153, Issue 7 (April 2008)
View table of contents by subject categoryCommentary
Commentary
A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism FREE
J Guindon and A G Hohmann
Br J Pharmacol 153: 1341-1343; advance online publication, February 25, 2008; doi:10.1038/bjp.2008.41
See also: Research Paper by Hu et al.Reviews
Review Article
Tumour endoproteases: the cutting edge of cancer drug delivery? FREE
J M Atkinson, C S Siller and J H Gill
Br J Pharmacol 153: 1344-1352; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707657
Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors FREE
P G Strange
Br J Pharmacol 153: 1353-1363; advance online publication, January 28, 2008; doi:10.1038/sj.bjp.0707672
Research Papers
Cancer Pharmacology
N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats
N Chen, K Aleksa, C Woodland, M Rieder and G Koren
Br J Pharmacol 153: 1364-1372; advance online publication, February 18, 2008; doi:10.1038/bjp.2008.15
5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene
H Hagiwara, H Sato, Y Ohde, Y Takano, T Seki, T Ariga, N Hokaiwado, M Asamoto, T Shirai, Y Nagashima and T Yano
Br J Pharmacol 153: 1373-1381; advance online publication, February 11, 2008; doi:10.1038/bjp.2008.17
Cardiovascular and pulmonary pharmacology
The flavonoid luteolin inhibits niacin-induced flush
D Papaliodis, W Boucher, D Kempuraj and T C Theoharides
Br J Pharmacol 153: 1382-1387; advance online publication, January 28, 2008; doi:10.1038/sj.bjp.0707668
Pioglitazone opposes neurogenic vascular dysfunction associated with chronic hyperinsulinaemia
S Takatori, Y Zamami, N Yabumae, N Hanafusa, M Mio, T Egawa and H Kawasaki
Br J Pharmacol 153: 1388-1398; advance online publication, February 4, 2008; doi:10.1038/bjp.2008.8
Secretory PLA2 inhibitor indoxam suppresses LDL modification and associated inflammatory responses in TNF
-stimulated human endothelial cells
K Sonoki, M Iwase, N Sasaki, S Ohdo, S Higuchi, Y Takata and M Iida
Br J Pharmacol 153: 1399-1408; advance online publication, February 11, 2008; doi:10.1038/bjp.2008.12
Agonists at PPAR-
suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts
G-H Hao, X-L Niu, D-F Gao, J Wei and N-P Wang
Br J Pharmacol 153: 1409-1419; advance online publication, February 18, 2008; doi:10.1038/bjp.2008.21
Activation of ETB receptors regulates the abundance of ET-1 mRNA in vascular endothelial cells
N Farhat, C C Matouk, A M Mamarbachi, P A Marsden, B G Allen and E Thorin
Br J Pharmacol 153: 1420-1431; advance online publication, February 18, 2008; doi:10.1038/bjp.2008.25
Genitourinary, renal and endocrine pharmacology
Analysis of the effects of oestrogen receptor (ER)- and ER
-selective ligands given in combination to ovariectomized rats
T Hertrampf, J Seibel, U Laudenbach, K H Fritzemeier and P Diel
Br J Pharmacol 153: 1432-1437; advance online publication, February 4, 2008; doi:10.1038/sj.bjp.0707664
Cholinergic nitric oxide release from the urinary bladder mucosa in cyclophosphamide-induced cystitis of the anaesthetized rat
M C Andersson, G Tobin and D Giglio
Br J Pharmacol 153: 1438-1444; advance online publication, February 4, 2008; doi:10.1038/bjp.2008.6
Oxidative stress and 1-adrenoceptor-mediated stimulation of the Cl-
/HCO3
-
exchanger in immortalized SHR proximal tubular epithelial cells
S Simão, S Fraga, P A Jose and P Soares-da-Silva
Br J Pharmacol 153: 1445-1455; advance online publication, February 25, 2008; doi:10.1038/bjp.2008.16
Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway
J-M Zheng, J-M Zhu, L-S Li and Z-H Liu
Br J Pharmacol 153: 1456-1464; advance online publication, February 11, 2008; doi:10.1038/bjp.2008.26
Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?
P Sadananda, R Chess-Williams and E Burcher
Br J Pharmacol 153: 1465-1473; advance online publication, February 11, 2008; doi:10.1038/bjp.2008.29
Molecular and cellular mechanisms
Influence of the M3–M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
S Kracun, P C Harkness, A J Gibb and N S Millar
Br J Pharmacol 153: 1474-1484; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707676
Identification of the 1L-adrenoceptor in rat cerebral cortex and possible relationship between 1L- and 1A-adrenoceptors
S Morishima, F Suzuki, H Yoshiki, A S Md Anisuzzaman, Z S Sathi, T Tanaka and I Muramatsu
Br J Pharmacol 153: 1485-1494; advance online publication, January 28, 2008; doi:10.1038/sj.bjp.0707679
Probing the presence of the ligand-binding haem in cellular nitric oxide receptors
B Roy, E Mo, J Vernon and J Garthwaite
Br J Pharmacol 153: 1495-1504; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707687
Modulation of TRPC5 cation channels by halothane, chloroform and propofol
Y M Bahnasi, H M Wright, C J Milligan, A M Dedman, F Zeng, P M Hopkins, A N Bateson and D J Beech
Br J Pharmacol 153: 1505-1512; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707689
Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells
J Longden, E-L Cooke and S J Hill
Br J Pharmacol 153: 1513-1527; advance online publication, January 28, 2008; doi:10.1038/sj.bjp.0707691
Thrombin-promoted release of UDP-glucose from human astrocytoma cells
S M Kreda, L Seminario-Vidal, C van Heusden and E R Lazarowski
Br J Pharmacol 153: 1528-1537; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707692
Neuropharmacology
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NF
B activity
S Shu-Jung Hu, H B Bradshaw, J S-C Chen, B Tan and J Michael Walker
Br J Pharmacol 153: 1538-1549; advance online publication, February 25, 2008; doi:10.1038/bjp.2008.33
See also: Commentary by Guindon & HohmannEffect of peripheral obestatin on food intake and gastric emptying in ghrelin-knockout mice
I Depoortere, T Thijs, D Moechars, B De Smet, L Ver Donck and T L Peeters
Br J Pharmacol 153: 1550-1557; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707683
Gabapentin evoked changes in functional activity in nociceptive regions in the brain of the anaesthetized rat: an fMRI study
R J M Governo, P G Morris, C A Marsden and V Chapman
Br J Pharmacol 153: 1558-1567; advance online publication, February 11, 2008; doi:10.1038/bjp.2008.27
Pharmacokinetics, drug metabolism, toxicology
Pharmacokinetic interaction between DA-8159, a new erectogenic, and metformin in rats: competitive inhibition of metabolism via hepatic CYP3A1/2
Y H Choi, S J Chung and M G Lee
Br J Pharmacol 153: 1568-1578; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707680
Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide
H Xu, K M Williams, W S Liauw, M Murray, R O Day and A J McLachlan
Br J Pharmacol 153: 1579-1586; advance online publication, January 21, 2008; doi:10.1038/sj.bjp.0707685
