TABLE OF CONTENTS

Volume 153, Issue 3 (February 2008)

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Commentaries

Commentary

Curcumin: potential for hepatic fibrosis therapy? FREE

M A O'Connell and S A Rushworth

Br J Pharmacol 153: 403-405; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707580

Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon? FREE

M A G van der Heyden, M E Smits and M A Vos

Br J Pharmacol 153: 406-409; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707618

See also: Research Paper by Takemasa et al.
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Reviews

Review Article

Prostamides (prostaglandin-ethanolamides) and their pharmacology FREE

D F Woodward, Y Liang and A H-P Krauss

Br J Pharmacol 153: 410-419; advance online publication, August 27, 2007; doi:10.1038/sj.bjp.0707434

Neuropeptide Y Y2 receptor in health and disease FREE

S L Parker and A Balasubramaniam

Br J Pharmacol 153: 420-431; advance online publication, September 10, 2007; doi:10.1038/sj.bjp.0707445

Controversies

Pharmacological Onomastics: What's in a name? FREE

T P Kenakin

Br J Pharmacol 153: 432-438; advance online publication, August 13, 2007; doi:10.1038/sj.bjp.0707407

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Research Papers

Cardiovascular and pulmonary pharmacology

Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome

H Takemasa, T Nagatomo, H Abe, K Kawakami, T Igarashi, T Tsurugi, N Kabashima, M Tamura, M Okazaki, B P Delisle, C T January and Y Otsuji

Br J Pharmacol 153: 439-447; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707537

See also: Research Paper by Takemasa et al.
Chlorthalidone inhibits the KvLQT1 potassium current in guinea-pig ventricular myocytes and oocytes from Xenopus laevis

C Mancilla-Simbro, A López, E Martinez-Morales, E Soto-Perez-de-Celis, L Millan-PerezPeña, R Tsushima and E M Salinas-Stefanon

Br J Pharmacol 153: 448-458; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707579

Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation

P-A Paquette, D Duguay, R El- Ayoubi, A Menaouar, B Danalache, J Gutkowska, D DeBlois and S Mukaddam-Daher

Br J Pharmacol 153: 459-467; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707588

Gender-specific vascular effects elicited by chronic ethanol consumption in rats: a role for inducible nitric oxide synthase

C R Tirapelli, S Y Fukada, A Yogi, A Z Chignalia, R C Tostes, D Bonaventura, V L Lanchote, F Q Cunha and A M de Oliveira

Br J Pharmacol 153: 468-479; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707589

Differential effects of glucose on agonist-induced relaxations in human mesenteric and subcutaneous arteries

A MacKenzie, E J Cooper and F J Dowell

Br J Pharmacol 153: 480-487; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707592

Cardiac capsaicin-sensitive sensory nerves regulate myocardial relaxation via S-nitrosylation of SERCA: role of peroxynitrite

P Bencsik, K Kupai, Z Giricz, A Görbe, I Huliák, S Fürst, L Dux, T Csont, G Jancsó and P Ferdinandy

Br J Pharmacol 153: 488-496; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707599

Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteries

D Dou, X Zheng, X Qin, H Qi, L Liu, J U Raj and Y Gao

Br J Pharmacol 153: 497-507; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707600

Paraoxonase 1 gene transfer lowers vascular oxidative stress and improves vasomotor function in apolipoprotein E-deficient mice with pre-existing atherosclerosis

P-J Guns, T Van Assche, W Verreth, P Fransen, B Mackness, M Mackness, P Holvoet and H Bult

Br J Pharmacol 153: 508-516; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707585

Gastrointestinal pharmacology

Regional differences in nitrergic innervation of the smooth muscle of murine lower oesophageal sphincter

Y Zhang, H Mashimo and W G Paterson

Br J Pharmacol 153: 517-527; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707573

Immunopharmacology and inflammation

Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures

P X Elsas, T Queto, S C Mendonça-Sales, M I G Elsas, Y Kanaoka and B K Lam

Br J Pharmacol 153: 528-535; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707586

Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress

S K McMaster, M J Paul-Clark, M Walters, M Fleet, J Anandarajah, S Sriskandan and J A Mitchell

Br J Pharmacol 153: 536-543; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707595

Molecular and cellular mechanisms

Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue

E Fonfria, W C Clay, D S Levy, J A Goodwin, S Roman, G D Smith, J P Condreay and A D Michel

Br J Pharmacol 153: 544-556; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707596

Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling

A Chen and S Zheng

Br J Pharmacol 153: 557-567; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707542

Neuropharmacology

Effects of zileuton and montelukast in mouse experimental spinal cord injury

T Genovese, A Rossi, E Mazzon, R Di Paola, C Muià, R Caminiti, P Bramanti, L Sautebin and S Cuzzocrea

Br J Pharmacol 153: 568-582; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707577

Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats

C C Crestani, F H F Alves, L B Resstel and F M A Corrêa

Br J Pharmacol 153: 583-590; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707591

Role of alpha1-adrenoceptor subtypes in the effects of methylenedioxy methamphetamine (MDMA) on body temperature in the mouse

S Bexis and J R Docherty

Br J Pharmacol 153: 591-597; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707590

Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate

P Li, D E Reichert, A D Rodríguez, B D Manion, A S Evers, V A Eterovic acute, J H Steinbach and G Akk

Br J Pharmacol 153: 598-608; advance online publication, November 26, 2007; doi:10.1038/sj.bjp.0707597

Activities of mixed NOP and mu-opioid receptor ligands

B Spagnolo, G Calo, W E Polgar, F Jiang, C M Olsen, I Berzetei-Gurske, T V Khroyan, S M Husbands, J W Lewis, L Toll and N T Zaveri

Br J Pharmacol 153: 609-619; advance online publication, December 3, 2007; doi:10.1038/sj.bjp.0707598

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Corrigendum

Internalization: what does it tell us about pharmacokinetic and pharmacodynamic properties of an antagonist? FREE

A Mueller

Br J Pharmacol 153: 620; doi:10.1038/sj.bjp.0707671

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Erratum

Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression FREE

J-C Zhong, X-Y Yu, Q-X Lin, X-H Li, X-Z Huang, D-Z Xiao and S-G Lin

Br J Pharmacol 153: 621; doi:10.1038/sj.bjp.0707614

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