TABLE OF CONTENTS

Volume 153, Issue 1 (January 2008)

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Commentaries

Commentary

Reperfusion and calculated RISKs: pharmacological postconditioning of human myocardium FREE

G F Baxter and D S Burley

Br J Pharmacol 153: 1-3; advance online publication, October 22, 2007; doi:10.1038/sj.bjp.0707498

See also: Research Paper by Mudalagiri et al.
Evidence against C-type natriuretic peptide as an arterial 'EDHF' FREE

C J Garland and K A Dora

Br J Pharmacol 153: 4-5; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707520

See also: Research Paper by Leuranguer et al.
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Reviews

Review Article

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors FREE

A Negre-Salvayre, C Coatrieux, C Ingueneau and R Salvayre

Br J Pharmacol 153: 6-20; advance online publication, July 23, 2007; doi:10.1038/sj.bjp.0707395

Inflammatory response and cardioprotection during open-heart surgery: the importance of anaesthetics FREE

M-S Suleiman, K Zacharowski and G D Angelini

Br J Pharmacol 153: 21-33; advance online publication, October 22, 2007; doi:10.1038/sj.bjp.0707526

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Research Papers

Cancer Pharmacology

[Pt(O,O'-acac)(bold gamma-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway FREE

A Muscella, N Calabriso, F P Fanizzi, S A De Pascali, L Urso, A Ciccarese, D Migoni and S Marsigliante

Br J Pharmacol 153: 34-49; advance online publication, November 19, 2007; doi:10.1038/sj.bjp.0707576

Cardiovascular and pulmonary pharmacology

Erythropoietin protects the human myocardium against hypoxia/reoxygenation injury via phosphatidylinositol-3 kinase and ERK1/2 activation FREE

N R Mudalagiri, M M Mocanu, C Di Salvo, S Kolvekar, M Hayward, J Yap, B Keogh and D M Yellon

Br J Pharmacol 153: 50-56; advance online publication, October 22, 2007; doi:10.1038/sj.bjp.0707461

See also: Commentary by Baxter & Burley
C-type natriuretic peptide and endothelium-dependent hyperpolarization in the guinea-pig carotid artery FREE

V Leuranguer, P M Vanhoutte, T Verbeuren and M Félétou

Br J Pharmacol 153: 57-65; advance online publication, October 1, 2007; doi:10.1038/sj.bjp.0707476

See also: Commentary by Garland & Dora
Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression FREE

J-C Zhong, X-Y Yu, Q-X Lin, X-H Li, X-Z Huang, D-Z Xiao and S-G Lin

Br J Pharmacol 153: 66-74; advance online publication, October 1, 2007; doi:10.1038/sj.bjp.0707482

Relevance of anaesthesia for dofetilide-induced torsades de pointes in alpha1-adrenoceptor-stimulated rabbits FREE

D Vincze, A S Farkas, L Rudas, P Makra, N Csík, I Leprán, T Forster, M Csanády, J G Papp, A Varró and A Farkas

Br J Pharmacol 153: 75-89; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707536

Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers FREE

S Hanafy, N J Dagenais, W F Dryden and F Jamali

Br J Pharmacol 153: 90-99; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707538

The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia–reperfusion injury in the isolated rabbit heart FREE

G Rossoni, A Sparatore, V Tazzari, B Manfredi, P Del Soldato and F Berti

Br J Pharmacol 153: 100-109; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707540

Electromechanical characterization of cinnamophilin, a natural thromboxane A2 receptor antagonist with anti-arrhythmic activity, in guinea-pig heart FREE

G-J Chang, M-J Su, T-S Wu, W-P Chen and C-M Kuo

Br J Pharmacol 153: 110-123; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707541

The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro  FREE

N J Mutch, N R Moore, C Mattsson, H Jonasson, A R Green and N A Booth

Br J Pharmacol 153: 124-131; advance online publication, November 5, 2007; doi:10.1038/sj.bjp.0707543

Effects of chronic in vivo administration of nitroglycerine on ACh-induced endothelium-dependent relaxation in rabbit cerebral arteries FREE

Y Watanabe, N Kusama and T Itoh

Br J Pharmacol 153: 132-139; advance online publication, October 29, 2007; doi:10.1038/sj.bjp.0707562

Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools FREE

S Salomone, E M Potts, S Tyndall, P C Ip, J Chun, V Brinkmann and C Waeber

Br J Pharmacol 153: 140-147; advance online publication, November 19, 2007; doi:10.1038/sj.bjp.0707581

Immunopharmacology and inflammation

Platelet-dependent accumulation of leukocytes in sinusoids mediates hepatocellular damage in bile duct ligation-induced cholestasis FREE

M W Laschke, S Dold, M D Menger, B Jeppsson and H Thorlacius

Br J Pharmacol 153: 148-156; advance online publication, November 19, 2007; doi:10.1038/sj.bjp.0707578

Neuropharmacology

AS601245, a c-Jun NH2-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils FREE

S Carboni, U Boschert, P Gaillard, J-P Gotteland, J-Y Gillon and P-A Vitte

Br J Pharmacol 153: 157-163; advance online publication, November 19, 2007; doi:10.1038/sj.bjp.0707574

Pharmacokinetics, drug metabolism, toxicology

Contribution of the active metabolite M1 to the pharmacological activity of tesofensine in vivo: a pharmacokinetic-pharmacodynamic modelling approach FREE

T Lehr, A Staab, C Tillmann, E Ø Nielsen, D Trommeshauser, H G Schaefer and C Kloft

Br J Pharmacol 153: 164-174; advance online publication, November 5, 2007; doi:10.1038/sj.bjp.0707539

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Erratum

[Pt(O,O'-acac)(bold gamma-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway FREE

A Muscella, N Calabriso, F P Fanizzi, S A De Pascali, L Urso, A Ciccarese, D Migoni and S Marsigliante

Br J Pharmacol 153: 175; doi:10.1038/sj.bjp.0707646

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