TABLE OF CONTENTS
Volume 152, Issue 5 (November 2007)
Themed issue: Cannabinoid pharmacology
PubMed lists over 6,000 records for cannabinoids in 2006, indicating the level of interest in the scientific community. It is an exciting time to be involved in cannabinoid research as reflected in the growing number of international scientific meetings on cannabinoids or cannabinoid-related topics. One of these, organized in Nottingham by Steve Alexander, Victoria Chapman, Dave Kendall and Michael Randall, was the British Pharmacological Society Focused Meeting on Cannabinoids/3rd European Workshop on Cannabinoid Research (April 2007).
This special themed issue on cannabinoids, guest edited by Steve Alexander and Michael Randall, contains 12 review articles related to topics presented at the British Pharmacological Society Focused Meeting/3rd European Workshop, as well as a series of 15-20 original articles.
Review Article |
Molecular and cellular mechanisms |
Neuropharmacology |
Cardiovascular and pulmonary pharmacology |
Pharmacokinetics, drug metabolism, toxicology
Commentary
Cannabinoids and their actions FREE
S P H Alexander and M Randall
Br J Pharmacol 152: 557-558; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707483
See also: Review by Alexander & KendallSee also: Review by Baker et al. See also: Review by BrownSee also: Review by Campbell & GowranSee also: Review by FowlerSee also: Review by Jhaveri et al. See also: Review by Matias et al. See also: Review by McPartland et al. See also: Review by O'SullivanSee also: Review by RandallSee also: Review by Rea et al. See also: Review by SangerGPR55 and the vascular receptors for cannabinoids FREE
C R Hiley and S S Kaup
Br J Pharmacol 152: 559-561; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707421
See also: Research Paper by Johns et al.Cannabis reward: biased towards the fairer sex? FREE
I S McGregor and J C Arnold
Br J Pharmacol 152: 562-564; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707469
See also: Research Paper by Fattore et al.Tuning the endocannabinoid system: allosteric modulators of the CB1 receptor FREE
R A Ross
Br J Pharmacol 152: 565-566; advance online publication, June 25, 2007; doi:10.1038/sj.bjp.0707349
See also: Research Paper by Horswill et al.Review Article
Novel cannabinoid receptors FREE
A J Brown
Br J Pharmacol 152: 567-575; advance online publication, October 1, 2007; doi:10.1038/sj.bjp.0707481
See also: Commentary by Hiley & KaupSee also: Research Paper by Johns et al. See also: Commentary by Alexander & RandallCannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors FREE
S E O'Sullivan
Br J Pharmacol 152: 576-582; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707423
Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences FREE
J M McPartland, M Glass and R G Pertwee
Br J Pharmacol 152: 583-593; advance online publication, July 16, 2007; doi:10.1038/sj.bjp.0707399
Abstract | Full Text | PDF | Supplementary information
See also: Commentary by Alexander & RandallThe contribution of cyclooxygenase-2 to endocannabinoid metabolism and action FREE
C J Fowler
Br J Pharmacol 152: 594-601; advance online publication, July 9, 2007; doi:10.1038/sj.bjp.0707379
See also: Commentary by Alexander & RandallThe complications of promiscuity: endocannabinoid action and metabolism FREE
S P H Alexander and D A Kendall
Br J Pharmacol 152: 602-623; advance online publication, September 17, 2007; doi:10.1038/sj.bjp.0707456
See also: Commentary by Alexander & RandallEndocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain FREE
M D Jhaveri, D Richardson and V Chapman
Br J Pharmacol 152: 624-632; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707433
See also: Commentary by Alexander & RandallSupraspinal modulation of pain by cannabinoids: the role of GABA and glutamate FREE
K Rea, M Roche and D P Finn
Br J Pharmacol 152: 633-648; advance online publication, September 10, 2007; doi:10.1038/sj.bjp.0707440
See also: Commentary by Alexander & RandallCannabinoid control of neuroinflammation related to multiple sclerosis FREE
D Baker, S J Jackson and G Pryce
Br J Pharmacol 152: 649-654; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707458
See also: Commentary by Alexander & RandallAlzheimer's disease; taking the edge off with cannabinoids? FREE
V A Campbell and A Gowran
Br J Pharmacol 152: 655-662; advance online publication, September 10, 2007; doi:10.1038/sj.bjp.0707446
See also: Commentary by Alexander & RandallEndocannabinoids and the gastrointestinal tract: what are the key questions? FREE
G J Sanger
Br J Pharmacol 152: 663-670; advance online publication, September 3, 2007; doi:10.1038/sj.bjp.0707422
See also: Commentary by Alexander & RandallEndocannabinoids and the haematological system FREE
M D Randall
Br J Pharmacol 152: 671-675; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707420
See also: Commentary by Alexander & RandallRole and regulation of acylethanolamides in energy balance: focus on adipocytes and 
-cells FREE
I Matias, M-P Gonthier, S Petrosino, L Docimo, R Capasso, L Hoareau, P Monteleone, R Roche, A A Izzo and V Di Marzo
Br J Pharmacol 152: 676-690; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707424
See also: Commentary by Alexander & RandallMolecular and cellular mechanisms
Cannabinoid activation of PPAR
; a novel neuroprotective mechanism
Y Sun, S P H Alexander, M J Garle, C L Gibson, K Hewitt, S P Murphy, D A Kendall and A J Bennett
Br J Pharmacol 152: 734-743; advance online publication, October 1, 2007; doi:10.1038/sj.bjp.0707478
Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake
L Thors, J Eriksson and C J Fowler
Br J Pharmacol 152: 744-750; advance online publication, August 6, 2007; doi:10.1038/sj.bjp.0707401
Vascular pharmacology of a novel cannabinoid-like compound, 3-(5-dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide (VSN16) in the rat
P M Hoi, C Visintin, M Okuyama, S M Gardiner, S S Kaup, T Bennett, D Baker, D L Selwood and C R Hiley
Br J Pharmacol 152: 751-764; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707470
Neuropharmacology
Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats
E J Rahn, A Makriyannis and A G Hohmann
Br J Pharmacol 152: 765-777; advance online publication, June 18, 2007; doi:10.1038/sj.bjp.0707333
Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide
E L Veale, R Buswell, C E Clarke and A Mathie
Br J Pharmacol 152: 778-786; advance online publication, September 10, 2007; doi:10.1038/sj.bjp.0707436
The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation
F Comelli, G Giagnoni, I Bettoni, M Colleoni and B Costa
Br J Pharmacol 152: 787-794; advance online publication, August 13, 2007; doi:10.1038/sj.bjp.0707425
Cannabinoid self-administration in rats: sex differences and the influence of ovarian function
L Fattore, M S Spano, S Altea, F Angius, P Fadda and W Fratta
Br J Pharmacol 152: 795-804; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707465
See also: Commentary by McGregor & ArnoldPSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats
J G Horswill, U Bali, S Shaaban, J F Keily, P Jeevaratnam, A J Babbs, C Reynet and P Wong Kai In
Br J Pharmacol 152: 805-814; advance online publication, June 25, 2007; doi:10.1038/sj.bjp.0707347
See also: Commentary by RossCardiovascular and pulmonary pharmacology
Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619
C J Hillard, W-Sv Ho, J Thompson, K M Gauthier, C E Wheelock, H Huang and B D Hammock
Br J Pharmacol 152: 691-698; advance online publication, September 24, 2007; doi:10.1038/sj.bjp.0707468
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta
E Herradón, M I Martín and V López-Miranda
Br J Pharmacol 152: 699-708; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707404
9-Tetrahydrocannabinol inhibits electrically-evoked CGRP release and capsaicin-sensitive sensory neurogenic vasodilatation in the rat mesenteric arterial bed
J D Wilkinson, D A Kendall and V Ralevic
Br J Pharmacol 152: 709-716; advance online publication, September 10, 2007; doi:10.1038/sj.bjp.0707448
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats
A J Wheal, T Bennett, M D Randall and S M Gardiner
Br J Pharmacol 152: 717-724; advance online publication, August 13, 2007; doi:10.1038/sj.bjp.0707410
Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed
P Pakdeechote, W R Dunn and V Ralevic
Br J Pharmacol 152: 725-733; advance online publication, July 16, 2007; doi:10.1038/sj.bjp.0707397
Pharmacokinetics, drug metabolism, toxicology
The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids
M L Holland, D T T Lau, J D Allen and J C Arnold
Br J Pharmacol 152: 815-824; advance online publication, October 1, 2007; doi:10.1038/sj.bjp.0707467
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
D G Johns, D J Behm, D J Walker, Z Ao, E M Shapland, D A Daniels, M Riddick, S Dowell, P C Staton, P Green, U Shabon, W Bao, N Aiyar, T-L Yue, A J Brown, A D Morrison and S A Douglas
Br J Pharmacol 152: 825-831; advance online publication, August 20, 2007; doi:10.1038/sj.bjp.0707419
See also: Commentary by Hiley & Kaup
