British Journal of Pharmacology

FIGURE 2

FROM:

Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain

M D Jhaveri, D Richardson and V Chapman

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Figure 2.

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(a) Effects of spinal nerve ligation (SNL) versus sham-surgery on levels of AEA in the hindpaw skin of vehicle-treated rats. (b) Effects of intraplantar injection of URB597 (URB, 25 mug in 50 mul) on levels of AEA, 2AG and PEA in the hindpaw skin of sham-operated rats. Data were analysed using Mann–Whitney non-parametric test and are expressed as a percentage of the contralateral value+s.e.mean. (n=6 rats per group). * P<0.05, ** P<0.01 ipsilateral versus contralateral hindpaw. AEA, anandamide; 2AG, 2-arachidonoylglycerol; PEA, palmitoyl ethanolamide. Modified from Jhaveri et al. (2006). Copyright © 2006 Society for Neuroscience.

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