TABLE OF CONTENTS

Volume 152, Issue 1 (September 2007)

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Commentary

High-throughput microscopy must re-invent the microscope rather than speed up its functions FREE

M Oheim

Br J Pharmacol 152: 1-4; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707348

See also: Review by Starkuviene & Pepperkok
Chemogenomic approaches to drug discovery: similar receptors bind similar ligands FREE

T Klabunde

Br J Pharmacol 152: 5-7; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707308

See also: Review by Rognan

Review Article

In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling FREE

S Ekins, J Mestres and B Testa

Br J Pharmacol 152: 9-20; advance online publication, June 4, 2007; doi:10.1038/sj.bjp.0707305

See also: Review by Ekins et al.
In silico pharmacology for drug discovery: applications to targets and beyond FREE

S Ekins, J Mestres and B Testa

Br J Pharmacol 152: 21-37; advance online publication, June 4, 2007; doi:10.1038/sj.bjp.0707306

See also: Review by Ekins et al.
Chemogenomic approaches to rational drug design FREE

D Rognan

Br J Pharmacol 152: 38-52; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707307

See also: Commentary by Klabunde
Origin and evolution of high throughput screening FREE

D A Pereira and J A Williams

Br J Pharmacol 152: 53-61; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707373

The potential of high-content high-throughput microscopy in drug discovery FREE

V Starkuviene and R Pepperkok

Br J Pharmacol 152: 62-71; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707346

See also: Commentary by Oheim

Molecular and cellular mechanisms

Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293 cells FREE

J Shi, S Takahashi, X-H Jin, Y-Q Li, Y Ito, Y Mori and R Inoue

Br J Pharmacol 152: 122-131; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707368

A functional comparison of recombinant and native somatostatin sst2 receptor variants in epithelia FREE

N D Holliday, I R Tough and H M Cox

Br J Pharmacol 152: 132-140; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707365

Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases FREE

S A Lévesque, É G Lavoie, J Lecka, F Bigonnesse and J Sévigny

Br J Pharmacol 152: 141-150; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707361

Neuropharmacology

Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models FREE

G Gigler, K Móricz, M ágoston, A Simó, M Albert, A Benedek, G Kapus, S Kertész, M Vegh, J Barkóczy, B Markó, G Szabó, É Matucz, I Gacsályi, G Lévay, L G Hársing Jr and G Szénási

Br J Pharmacol 152: 151-160; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707362

Intraglandular application of botulinum toxin leads to structural and functional changes in rat acinar cells FREE

A Teymoortash, F Sommer, R Mandic, S Schulz, M Bette, G Aumüller and J A Werner

Br J Pharmacol 152: 161-167; advance online publication, July 9, 2007; doi:10.1038/sj.bjp.0707375

Cardiovascular and pulmonary pharmacology

Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization FREE

M C Chang, B J Uang, C Y Tsai, H L Wu, B R Lin, C S Lee, Y J Chen, C H Chang, Y L Tsai, C J Kao and J H Jeng

Br J Pharmacol 152: 73-82; advance online publication, July 16, 2007; doi:10.1038/sj.bjp.0707367

Synergistic effect of formoterol and mometasone in a mouse model of allergic lung inflammation FREE

D Wyss, O Bonneau and A Trifilieff

Br J Pharmacol 152: 83-90; advance online publication, July 9, 2007; doi:10.1038/sj.bjp.0707381

Role of alpha 2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice FREE

M Honda, M Suzuki, K Nakayama and T Ishikawa

Br J Pharmacol 152: 91-100; advance online publication, July 9, 2007; doi:10.1038/sj.bjp.0707380

Role of InsP3 and ryanodine receptors in the activation of capacitative Ca2+ entry by store depletion or hypoxia in canine pulmonary arterial smooth muscle cells FREE

L C Ng, S M Wilson, C E McAllister and J R Hume

Br J Pharmacol 152: 101-111; advance online publication, June 25, 2007; doi:10.1038/sj.bjp.0707357

Drug Discovery

In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors FREE

J J N Silva, A L Osakabe, W R Pavanelli, J S Silva and D W Franco

Br J Pharmacol 152: 112-121; advance online publication, July 2, 2007; doi:10.1038/sj.bjp.0707363

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