TABLE OF CONTENTS

Volume 151, Issue 6 (July 2007)

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Commentaries

Commentary

Taking the sting out of pain FREE

I Nagy, C Paule, J White and L Urban

Br J Pharmacol 151: 721-722; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707274

See also: Research Paper by Mortari et al.
Two new non-competitive mGlu1 receptor antagonists are potent tools to unravel functions of this mGlu receptor subtype FREE

T Knöpfel

Br J Pharmacol 151: 723-724; advance online publication, May 14, 2007; doi:10.1038/sj.bjp.0707289

See also: Research Paper by Fukunaga et al.
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Reviews

Review Article

Chemokines and their receptors as potential targets for the treatment of asthma FREE

C Palmqvist, A J Wardlaw and P Bradding

Br J Pharmacol 151: 725-736; advance online publication, April 30, 2007; doi:10.1038/sj.bjp.0707263

Tricyclic antidepressant pharmacology and therapeutic drug interactions updated FREE

P K Gillman

Br J Pharmacol 151: 737-748; advance online publication, April 30, 2007; doi:10.1038/sj.bjp.0707253

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Research Papers

Biopharmaceuticals

Mutations at F637 in the NMDA receptor NR2A subunit M3 domain influence agonist potency, ion channel gating and alcohol action FREE

H Ren, A K Salous, J M Paul, R H Lipsky and R W Peoples

Br J Pharmacol 151: 749-757; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707254

Cardiovascular and pulmonary pharmacology

Molecular expression and pharmacological identification of a role for Kv7 channels in murine vascular reactivity FREE

S Y M Yeung, V Pucovský, J D Moffatt, L Saldanha, M Schwake, S Ohya and I A Greenwood

Br J Pharmacol 151: 758-770; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707284

Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats FREE

D Lebrecht, A Geist, U-P Ketelsen, J Haberstroh, B Setzer and U A Walker

Br J Pharmacol 151: 771-778; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707294

Treprostinil potentiates the positive inotropic effect of catecholamines in adult rat ventricular cardiomyocytes FREE

M Fontana, H Olschewski, A Olschewski and K-D Schlüter

Br J Pharmacol 151: 779-786; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707300

Activation of the ERK signalling pathway contributes to the adaptive changes in rat hearts during naloxone-induced morphine withdrawal FREE

P Almela, M V Milanés and M L Laorden

Br J Pharmacol 151: 787-797; advance online publication, June 4, 2007; doi:10.1038/sj.bjp.0707301

Drug Discovery

A-272651, a nonpeptidic blocker of large-conductance Ca2+-activated K+ channels, modulates bladder smooth muscle contractility and neuronal action potentials FREE

C-C Shieh, S C Turner, X-F Zhang, I Milicic, A Parihar, T Jinkerson, J Wilkins, S A Buckner and M Gopalakrishnan

Br J Pharmacol 151: 798-806; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707278

Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARbold italic gamma and Pref-1 expression BJPOpen

A C Nicholson, D P Hajjar, X Zhou, W He, A M Gotto Jr and J Han

Br J Pharmacol 151: 807-815; advance online publication, June 4, 2007; doi:10.1038/sj.bjp.0707250

Gastrointestinal pharmacology

Different profiles of Ca2+ responses to endothelin-1 and PDGF in liver myofibroblasts during the process of cell differentiation FREE

N Kojima, M Hori, T Murata, Y Morizane and H Ozaki

Br J Pharmacol 151: 816-827; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707269

Genitourinary, renal and endocrine pharmacology

K+ channel modulation of slow wave activity in the guinea-pig prostate FREE

D-T T Nguyen, R J Lang and B Exintaris

Br J Pharmacol 151: 828-836; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707283

Immunopharmacology and inflammation

Size-fractionated heparins have differential effects on human neutrophil function in vitro  FREE

R Lever, W T Lo, M Faraidoun, V Amin, R A Brown, J Gallagher and C P Page

Br J Pharmacol 151: 837-843; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707298

Apoptotic mimicry: phosphatidylserine liposomes reduce inflammation through activation of peroxisome proliferator-activated receptors (PPARs) in vivo  FREE

G C Ramos, D Fernandes, C T Charão, D G Souza, M M Teixeira and J Assreuy

Br J Pharmacol 151: 844-850; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707302

Molecular and cellular mechanisms

Achieving signalling selectivity of ligands for the corticotropin-releasing factor type 1 receptor by modifying the agonist's signalling domain FREE

M Beyermann, N Heinrich, K Fechner, J Furkert, W Zhang, O Kraetke, M Bienert and H Berger

Br J Pharmacol 151: 851-859; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707293

Neuropharmacology

Inhibition of acute nociceptive responses in rats after i.c.v. injection of Thr6-bradykinin, isolated from the venom of the social wasp, Polybia occidentalis  FREE

M R Mortari, A O S Cunha, R O G Carolino, J Coutinho-Netto, J C Tomaz, N P Lopes, N C Coimbra and W F dos Santos

Br J Pharmacol 151: 860-869; advance online publication, May 29, 2007; doi:10.1038/sj.bjp.0707275

See also: Commentary by Nagy et al.
Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices FREE

I Fukunaga, C H Yeo and A M Batchelor

Br J Pharmacol 151: 870-876; advance online publication, May 14, 2007; doi:10.1038/sj.bjp.0707286

See also: Commentary by Knöpfel
Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of mu- and delta-opioid receptor antagonists FREE

N S Abul-Husn, M Sutak, B Milne and K Jhamandas

Br J Pharmacol 151: 877-887; advance online publication, May 14, 2007; doi:10.1038/sj.bjp.0707277

The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle FREE

S Verma, A P Robertson and R J Martin

Br J Pharmacol 151: 888-899; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707296

Blockade of MCH1 receptor signalling ameliorates obesity and related hepatic steatosis in ovariectomized mice FREE

A Gomori, A Ishihara, M Ito, H Matsushita, M Ito, S Mashiko, H Iwaasa, M Matsuda, M A Bednarek, S Qian, D J MacNeil and A Kanatani

Br J Pharmacol 151: 900-908; advance online publication, May 21, 2007; doi:10.1038/sj.bjp.0707292

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