BJP Anniversary supplement cover

2006 is the 75th Anniversary of the founding of the British Pharmacological Society, and the 60th Anniversary of the first issue of its Journal, BJP, the British Journal of Pharmacology. To commemorate these important anniversaries, BJP is publishing a special supplement, comprising a series of articles by distinguished scientists who have been actively involved in areas of the subject in which British pharmacologists have made a major contribution.

Starting with 35 general topics which we felt fairly represented these areas, we approached authors with a request to write contributions, and were delighted when nearly all of them accepted the task with enthusiasm. Authors were asked to adopt a readable and narrative style to show how ideas arose and evolved, without constraints – apart from length – on how they approached the task. The result is a unique and varied series of articles which encapsulates the stories of many of the major pharmacological discoveries of past half-century, which we hope will be useful and interesting to pharmacologists young and old.

This supplement has been edited by Dr Y S Bakhle, Prof C P Page and Prof H P Rang.

The BJP would like to thank all the authors who contributed to this supplement.

TABLE OF CONTENTS

Volume 147, Issue S1 (January 2006)

View table of contents by subject category
Top

Introduction

Review Article

Introduction FREE

R Alan North

Br J Pharmacol 147: S1-S1; doi:10.1038/sj.bjp.0706499

A brief history of the British Pharmacological Society FREE

Alan W Cuthbert

Br J Pharmacol 147: S2-S8; doi:10.1038/sj.bjp.0706496

Top

General Topics

Review Article

The receptor concept: pharmacology's big idea FREE

H P Rang

Br J Pharmacol 147: S9-S16; doi:10.1038/sj.bjp.0706457

Agonist-activated ion channels FREE

David Colquhoun

Br J Pharmacol 147: S17-S26; doi:10.1038/sj.bjp.0706502

G-protein-coupled receptors: past, present and future FREE

Stephen J Hill

Br J Pharmacol 147: S27-S37; doi:10.1038/sj.bjp.0706455

Pharmacology of intracellular signalling pathways FREE

Stefan R Nahorski

Br J Pharmacol 147: S38-S45; doi:10.1038/sj.bjp.0706468

Heterotrimeric G-proteins: a short history FREE

Graeme Milligan and Evi Kostenis

Br J Pharmacol 147: S46-S55; doi:10.1038/sj.bjp.0706405

A short history of voltage-gated calcium channels FREE

Annette C Dolphin

Br J Pharmacol 147: S56-S62; doi:10.1038/sj.bjp.0706442

Potassium channels – multiplicity and challenges FREE

Donald H Jenkinson

Br J Pharmacol 147: S63-S71; doi:10.1038/sj.bjp.0706447

Molecular targets underlying general anaesthesia FREE

Nicholas P Franks

Br J Pharmacol 147: S72-S81; doi:10.1038/sj.bjp.0706441

Neurotransmitter transporters and their impact on the development of psychopharmacology FREE

Leslie Iversen

Br J Pharmacol 147: S82-S88; doi:10.1038/sj.bjp.0706428

Drug metabolism and pharmacogenetics: the British contribution to fields of international significance FREE

John Caldwell

Br J Pharmacol 147: S89-S99; doi:10.1038/sj.bjp.0706466

The glutamate story FREE

Jeffrey C Watkins and David E Jane

Br J Pharmacol 147: S100-S108; doi:10.1038/sj.bjp.0706444

GABA and glycine as neurotransmitters: a brief history FREE

N G Bowery and T G Smart

Br J Pharmacol 147: S109-S119; doi:10.1038/sj.bjp.0706443

Acetylcholine FREE

David A Brown

Br J Pharmacol 147: S120-S126; doi:10.1038/sj.bjp.0706474

Histamine and its receptors FREE

Mike E Parsons and C Robin Ganellin

Br J Pharmacol 147: S127-S135; doi:10.1038/sj.bjp.0706440

Dopamine: the rewarding years FREE

Charles A Marsden

Br J Pharmacol 147: S136-S144; doi:10.1038/sj.bjp.0706473

Neuropharmacology of 5-hydroxytryptamine FREE

A Richard Green

Br J Pharmacol 147: S145-S152; doi:10.1038/sj.bjp.0706427

75 years of opioid research: the exciting but vain quest for the Holy Grail FREE

Alistair D Corbett, Graeme Henderson, Alexander T McKnight and Stewart J Paterson

Br J Pharmacol 147: S153-S162; doi:10.1038/sj.bjp.0706435

Cannabinoid pharmacology: the first 66 years FREE

Roger G Pertwee

Br J Pharmacol 147: S163-S171; doi:10.1038/sj.bjp.0706406

Purinergic signalling FREE

Geoffrey Burnstock

Br J Pharmacol 147: S172-S181; doi:10.1038/sj.bjp.0706429

Prostaglandins, bioassay and inflammation FREE

R J Flower

Br J Pharmacol 147: S182-S192; doi:10.1038/sj.bjp.0706506

The discovery of nitric oxide and its role in vascular biology FREE

S Moncada and E A Higgs

Br J Pharmacol 147: S193-S201; doi:10.1038/sj.bjp.0706458

Neuropeptides and their receptors: innovative science providing novel therapeutic targets FREE

Susan D Brain and Helen M Cox

Br J Pharmacol 147: S202-S211; doi:10.1038/sj.bjp.0706461

The attraction of chemokines as a target for specific anti-inflammatory therapy FREE

James E Pease and Timothy J Williams

Br J Pharmacol 147: S212-S221; doi:10.1038/sj.bjp.0706475

Antiarrhythmic drug research FREE

M J A Walker

Br J Pharmacol 147: S222-S231; doi:10.1038/sj.bjp.0706500

The role of inflammation in CNS injury and disease FREE

Sian-Marie Lucas, Nancy J Rothwell and Rosemary M Gibson

Br J Pharmacol 147: S232-S240; doi:10.1038/sj.bjp.0706400

Antiplatelet drugs FREE

Gustav Born and Carlo Patrono

Br J Pharmacol 147: S241-S251; doi:10.1038/sj.bjp.0706401

Phosphodiesterase inhibitors FREE

Victoria Boswell-Smith, Domenico Spina and Clive P Page

Br J Pharmacol 147: S252-S257; doi:10.1038/sj.bjp.0706495

Glucocorticoids: exemplars of multi-tasking FREE

Julia C Buckingham

Br J Pharmacol 147: S258-S268; doi:10.1038/sj.bjp.0706456

Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer FREE

V Craig Jordan

Br J Pharmacol 147: S269-S276; doi:10.1038/sj.bjp.0706399

Neuromuscular block FREE

W C Bowman

Br J Pharmacol 147: S277-S286; doi:10.1038/sj.bjp.0706404

Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness FREE

Moussa B H Youdim and Y S Bakhle

Br J Pharmacol 147: S287-S296; doi:10.1038/sj.bjp.0706464

Drugs for asthma FREE

Peter J Barnes

Br J Pharmacol 147: S297-S303; doi:10.1038/sj.bjp.0706437

The future of pharmacology FREE

Patrick Vallance and Trevor G Smart

Br J Pharmacol 147: S304-S307; doi:10.1038/sj.bjp.0706454

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