
2006 is the 75th Anniversary of the founding of the British Pharmacological Society, and the 60th Anniversary of the first issue of its Journal, BJP, the British Journal of Pharmacology. To commemorate these important anniversaries, BJP is publishing a special supplement, comprising a series of articles by distinguished scientists who have been actively involved in areas of the subject in which British pharmacologists have made a major contribution.
Starting with 35 general topics which we felt fairly represented these areas, we approached authors with a request to write contributions, and were delighted when nearly all of them accepted the task with enthusiasm. Authors were asked to adopt a readable and narrative style to show how ideas arose and evolved, without constraints – apart from length – on how they approached the task. The result is a unique and varied series of articles which encapsulates the stories of many of the major pharmacological discoveries of past half-century, which we hope will be useful and interesting to pharmacologists young and old.
This supplement has been edited by Dr Y S Bakhle, Prof C P Page and Prof H P Rang.
The BJP would like to thank all the authors who contributed to this supplement.
TABLE OF CONTENTS
Volume 147, Issue S1 (January 2006)
View table of contents by subject categoryIntroduction
Review Article
Introduction FREE
R Alan North
Br J Pharmacol 147: S1-S1; doi:10.1038/sj.bjp.0706499
A brief history of the British Pharmacological Society FREE
Alan W Cuthbert
Br J Pharmacol 147: S2-S8; doi:10.1038/sj.bjp.0706496
General Topics
Review Article
The receptor concept: pharmacology's big idea FREE
H P Rang
Br J Pharmacol 147: S9-S16; doi:10.1038/sj.bjp.0706457
Agonist-activated ion channels FREE
David Colquhoun
Br J Pharmacol 147: S17-S26; doi:10.1038/sj.bjp.0706502
G-protein-coupled receptors: past, present and future FREE
Stephen J Hill
Br J Pharmacol 147: S27-S37; doi:10.1038/sj.bjp.0706455
Pharmacology of intracellular signalling pathways FREE
Stefan R Nahorski
Br J Pharmacol 147: S38-S45; doi:10.1038/sj.bjp.0706468
Heterotrimeric G-proteins: a short history FREE
Graeme Milligan and Evi Kostenis
Br J Pharmacol 147: S46-S55; doi:10.1038/sj.bjp.0706405
A short history of voltage-gated calcium channels FREE
Annette C Dolphin
Br J Pharmacol 147: S56-S62; doi:10.1038/sj.bjp.0706442
Potassium channels – multiplicity and challenges FREE
Donald H Jenkinson
Br J Pharmacol 147: S63-S71; doi:10.1038/sj.bjp.0706447
Molecular targets underlying general anaesthesia FREE
Nicholas P Franks
Br J Pharmacol 147: S72-S81; doi:10.1038/sj.bjp.0706441
Neurotransmitter transporters and their impact on the development of psychopharmacology FREE
Leslie Iversen
Br J Pharmacol 147: S82-S88; doi:10.1038/sj.bjp.0706428
Drug metabolism and pharmacogenetics: the British contribution to fields of international significance FREE
John Caldwell
Br J Pharmacol 147: S89-S99; doi:10.1038/sj.bjp.0706466
The glutamate story FREE
Jeffrey C Watkins and David E Jane
Br J Pharmacol 147: S100-S108; doi:10.1038/sj.bjp.0706444
GABA and glycine as neurotransmitters: a brief history FREE
N G Bowery and T G Smart
Br J Pharmacol 147: S109-S119; doi:10.1038/sj.bjp.0706443
Acetylcholine FREE
David A Brown
Br J Pharmacol 147: S120-S126; doi:10.1038/sj.bjp.0706474
Histamine and its receptors FREE
Mike E Parsons and C Robin Ganellin
Br J Pharmacol 147: S127-S135; doi:10.1038/sj.bjp.0706440
Dopamine: the rewarding years FREE
Charles A Marsden
Br J Pharmacol 147: S136-S144; doi:10.1038/sj.bjp.0706473
Neuropharmacology of 5-hydroxytryptamine FREE
A Richard Green
Br J Pharmacol 147: S145-S152; doi:10.1038/sj.bjp.0706427
75 years of opioid research: the exciting but vain quest for the Holy Grail FREE
Alistair D Corbett, Graeme Henderson, Alexander T McKnight and Stewart J Paterson
Br J Pharmacol 147: S153-S162; doi:10.1038/sj.bjp.0706435
Cannabinoid pharmacology: the first 66 years FREE
Roger G Pertwee
Br J Pharmacol 147: S163-S171; doi:10.1038/sj.bjp.0706406
Purinergic signalling FREE
Geoffrey Burnstock
Br J Pharmacol 147: S172-S181; doi:10.1038/sj.bjp.0706429
Prostaglandins, bioassay and inflammation FREE
R J Flower
Br J Pharmacol 147: S182-S192; doi:10.1038/sj.bjp.0706506
The discovery of nitric oxide and its role in vascular biology FREE
S Moncada and E A Higgs
Br J Pharmacol 147: S193-S201; doi:10.1038/sj.bjp.0706458
Neuropeptides and their receptors: innovative science providing novel therapeutic targets FREE
Susan D Brain and Helen M Cox
Br J Pharmacol 147: S202-S211; doi:10.1038/sj.bjp.0706461
The attraction of chemokines as a target for specific anti-inflammatory therapy FREE
James E Pease and Timothy J Williams
Br J Pharmacol 147: S212-S221; doi:10.1038/sj.bjp.0706475
Antiarrhythmic drug research FREE
M J A Walker
Br J Pharmacol 147: S222-S231; doi:10.1038/sj.bjp.0706500
The role of inflammation in CNS injury and disease FREE
Sian-Marie Lucas, Nancy J Rothwell and Rosemary M Gibson
Br J Pharmacol 147: S232-S240; doi:10.1038/sj.bjp.0706400
Antiplatelet drugs FREE
Gustav Born and Carlo Patrono
Br J Pharmacol 147: S241-S251; doi:10.1038/sj.bjp.0706401
Phosphodiesterase inhibitors FREE
Victoria Boswell-Smith, Domenico Spina and Clive P Page
Br J Pharmacol 147: S252-S257; doi:10.1038/sj.bjp.0706495
Glucocorticoids: exemplars of multi-tasking FREE
Julia C Buckingham
Br J Pharmacol 147: S258-S268; doi:10.1038/sj.bjp.0706456
Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer FREE
V Craig Jordan
Br J Pharmacol 147: S269-S276; doi:10.1038/sj.bjp.0706399
Neuromuscular block FREE
W C Bowman
Br J Pharmacol 147: S277-S286; doi:10.1038/sj.bjp.0706404
Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness FREE
Moussa B H Youdim and Y S Bakhle
Br J Pharmacol 147: S287-S296; doi:10.1038/sj.bjp.0706464
Drugs for asthma FREE
Peter J Barnes
Br J Pharmacol 147: S297-S303; doi:10.1038/sj.bjp.0706437





