FIGURE 5
FROM:
TRPV1 activation results in disruption of the blood–brain barrier in the rat
De-En Hu, Alexander S Easton and Paul A Fraser
BACK TO ARTICLEFigure 5.
The permeability response to capsaicin is inhibited by GR205171. (a) The effect of the NK1 antagonist GR205171 on venular permeability was plotted against concentration. (b) Dose–effect curves produced by coapplication of GR205171 (1–100 
M) with SP-o-Me; each curve mean of four vessels from four rats. (c) The effects of GR205171 (0.1–100
M) on the permeability response to capsaicin (100
M); ANOVA with Dunnett's multiple comparison test four vessels, **
P<0.01, six vessels from six rats. (d) Dose–effect curves produced by coapplication of GR205171 (1–100
M) with capsaicin; each curve mean of four vessels from four rats. All vessel diameters were between 8 and 15 m.