British Journal of Pharmacology

FIGURE 3

FROM:

TRPV1 activation results in disruption of the blood–brain barrier in the rat

De-En Hu, Alexander S Easton and Paul A Fraser

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Figure 3.

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Effects of CGRP on pial venular permeability. (a) The permeability effect of CGRP on the permeability of venules that had spontaneously become slightly leaky was plotted against concentration. Four vessels from four rats. (b) The effect of the CGRP receptor antagonist CGRP8--37 on the capsaicin dose–effect curve; four to 13 vessels for each of the curves, each vessel from a different animal. All the vessel diameters were between 8 and 15 mum.

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