British Journal of Pharmacology

FIGURE 2

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TRPV1 activation results in disruption of the blood–brain barrier in the rat

De-En Hu, Alexander S Easton and Paul A Fraser

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Figure 2.

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Effects of capsaicin, NK1 and NK2 agonists on pial venular permeability. The permeability effect of (a) the TRPV1 agonist capsaicin, (b) the NK1 agonist SP-o-Me and (c) the NK2 agonist beta-Ala(8)-NK4–10 was plotted against concentration. The data were obtained from six to 13 venular capillaries, diameters between 8 and 15 mum, each vessel from a separate animal, and displayed as meanplusminuss.e.m.

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