TABLE OF CONTENTS
Volume 145, Issue 8 (August 2005)
View table of contents by subject categoryReview
Review Article
The Quintiles Prize Lecture 2004: The identification of the adenosine A2B receptor as a novel therapeutic target in asthma FREE
Stephen T Holgate
Br J Pharmacol 145: 1009-1015; advance online publication, June 27, 2005; doi:10.1038/sj.bjp.0706272
Papers
Gastrointestinal pharmacology
Caveolin-1 gene knockout impairs nitrergic function in mouse small intestine FREE
Ahmed F El-Yazbi, Woo-Jung Cho, Geoffrey Boddy and Edwin E Daniel
Br J Pharmacol 145: 1017-1026; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706289
Immunopharmacology and inflammation
APT070 (Mirococept), a membrane-localised complement inhibitor, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury FREE
Danielle G Souza, Dirk Esser, Roberta Bradford, Angélica T Vieira and Mauro M Teixeira
Br J Pharmacol 145: 1027-1034; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706286
Neuropharmacology
Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats FREE
Izzettin Hatip-Al-Khatib, Katsunori Iwasaki, Yoshitaka Yoshimitsu, Takashi Arai, Nobuaki Egashira, Kenichi Mishima, Tomoaki Ikeda and Michihiro Fujiwara
Br J Pharmacol 145: 1035-1044; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706288
Molecular and cellular mechanisms
New positron emission tomography tracer [11C]carvedilol reveals P-glycoprotein modulation kinetics FREE
Joost Bart, Eli C F Dijkers, Theodora D Wegman, Elisabeth G E de Vries, Winette T A van der Graaf, Harry J M Groen, Willem Vaalburg, Antoon T M Willemsen and N Harry Hendrikse
Br J Pharmacol 145: 1045-1051; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706283
Immunopharmacology and inflammation
Differing mechanisms of leukocyte recruitment and sensitivity to conditioning by shear stress for endothelial cells treated with tumour necrosis factor-
or interleukin-1
FREE
Sajila Sheikh, Mahbub Rahman, Zoe Gale, N Thin Luu, Philip C W Stone, Nick M Matharu, G Edward Luu Rainger and Gerard B Nash
Br J Pharmacol 145: 1052-1061; advance online publication, May 23, 2005; doi:10.1038/sj.bjp.0706281
Mast cell-derived tumour necrosis factor- mediates macrophage inflammatory protein-2-induced recruitment of neutrophils in mice FREE
Yusheng Wang and Henrik Thorlacius
Br J Pharmacol 145: 1062-1068; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706274
Genitourinary, renal and endocrine pharmacology
Glibenclamide depletes ATP in renal proximal tubular cells by interfering with mitochondrial metabolism FREE
Richard Engbersen, Rosalinde Masereeuw, Miriam A van Gestel, Elise M J van der Logt, Paul Smits and Frans G M Russel
Br J Pharmacol 145: 1069-1075; advance online publication, May 23, 2005; doi:10.1038/sj.bjp.0706275
Cancer Pharmacology
4-Amino-5-benzoyl-2-(4-methoxyphenylamino)thiazole (DAT1): a cytotoxic agent towards cancer cells and a probe for tubulin-microtubule system FREE
Suparna Sengupta, Sasidharan L Smitha, Nisha E Thomas, Thankaiyyan R Santhoshkumar, Satyabhama K C Devi, Kumaran G Sreejalekshmi and Kallikat N Rajasekharan
Br J Pharmacol 145: 1076-1083; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706276
Neuropharmacology
Cellular responses to nicotinic receptor activation are decreased after prolonged exposure to galantamine in human neuroblastoma cells FREE
Jacques Barik, Federico Dajas-Bailador and Susan Wonnacott
Br J Pharmacol 145: 1084-1092; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706278
Molecular and cellular mechanisms
Characterisation of cell-penetrating peptide-mediated peptide delivery FREE
Simon W Jones, Richard Christison, Ken Bundell, Catherine J Voyce, Sarah M V Brockbank, Peter Newham and Mark A Lindsay
Br J Pharmacol 145: 1093-1102; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706279
Neuropharmacology
Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons FREE
Ester Verdaguer, Daniel Alvira, Andrés Jiménez, Victor Rimbau, Antoni Camins and Mercè Pallàs
Br J Pharmacol 145: 1103-1111; advance online publication, May 23, 2005; doi:10.1038/sj.bjp.0706280
Genitourinary, renal and endocrine pharmacology
Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney FREE
Klaus Höcherl, Corina Hensel, Bettina Ulbricht and Bernhard K Krämer
Br J Pharmacol 145: 1112-1122; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706259
Cardiovascular and pulmonary pharmacology
Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways FREE
Marcello Trevisani, Riccardo Patacchini, Paola Nicoletti, Raffaele Gatti, David Gazzieri, Nicola Lissi, Giovanni Zagli, Christophe Creminon, Pierangelo Geppetti and Selena Harrison
Br J Pharmacol 145: 1123-1131; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706277
Molecular and cellular mechanisms
A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3 is essential for agonist-induced phosphorylation, desensitization and internalization FREE
Frank Neuschäfer-Rube, Ricardo Hermosilla, Manuela Kuna, Andrea Pathe-Neuschäfer-Rube, Ralf Schülein and Gerhard Paul Püschel
Br J Pharmacol 145: 1132-1142; advance online publication, June 6, 2005; doi:10.1038/sj.bjp.0706282
Cardiovascular and pulmonary pharmacology
Dual regulation of myofilament Ca2+ sensitivity by levosimendan in normal and acidotic conditions in aequorin-loaded canine ventricular myocardium FREE
Reiko Takahashi and Masao Endoh
Br J Pharmacol 145: 1143-1152; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706292
Neuropharmacology
Distinct mixtures of muscarinic receptor subtypes mediate inhibition of noradrenaline release in different mouse peripheral tissues, as studied with receptor knockout mice FREE
Anne-Ulrike Trendelenburg, Angelika Meyer, Jürgen Wess and Klaus Starke
Br J Pharmacol 145: 1153-1159; advance online publication, June 20, 2005; doi:10.1038/sj.bjp.0706297
Cardiovascular and pulmonary pharmacology
Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice FREE
Kristin J Carpenter, Jillian L Ewing, Jane M Schuh, Traci L Ness, Steven L Kunkel, Monica Aparici, Montserrat Miralpeix and Cory M Hogaboam
Br J Pharmacol 145: 1160-1172; advance online publication, June 13, 2005; doi:10.1038/sj.bjp.0706243
