British Journal of Cancer - Table 2 for article: Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC

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Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC

A Kalikaki, A Koutsopoulos, M Trypaki, J Souglakos, E Stathopoulos, V Georgoulias, D Mavroudis and A Voutsina

	EGFR mutation status		EGFR expression		p-EGFR expression		K-RAS mutation status
Case	Primary	Metastasis	Primary	Metastasis	Primary	Metastasis	Primary	Metastasis	Gefitinib	Response
1	wt	wt	1+	1+	0	2+	wt	wt	No	—
2	wt	wt	3+	3+	1+	1+	wt	wt	No	—
3	wt	wt	0	1+	0	0	wt	wt	No	—
4	wt	wt	3+	2+	0	1+	wt	wt	No	—
5	wt	wt	0	0	0	0	wt	wt	No	—
6	wt	wt	1+	0	0	0	wt	wt	No	—
7	wt	wt	0	1+	0	0	wt	wt	No	—
8	wt	wt	1+	0	0	0	G12S	wt	No	—
9	wt	wt	1+	1+	0	1+	wt	G13S	No	—
10	wt	wt	2+	3+	0	0	G12V	G12V	No	—
11	wt	wt	ND	2+	ND	2+	wt	G12S	No	—
12	wt	L692P V717A	1+	0	ND	2+	wt	wt	No	—
13	wt	T847A	0	0	0	1+	wt	wt	No	—
14	wt	wt	3+	0	1+	0	wt	wt	Yes	PD
15	wt	wt	0	2+	ND	2+	wt	wt	Yes	PD
16	wt	wt	0	0	0	2+	wt	G12A	Yes	PD
17	L692P	wt	0	1+	0	0	wt	wt	Yes	SD
18	E746V	wt	0	0	ND	0	wt	wt	Yes	SD
19	G857E	wt	0	0	0	1+	wt	wt	Yes	SD
20	E746-A750 del	E746-A750 del T790M	2+	3+	2+	0	wt	wt	Yes	SD
21	wt	wt	ND	ND	ND	ND	wt	wt	No	—
22	wt	wt	ND	ND	ND	ND	G12D	wt	Yes	PD
23	E746-A750 del	wt	ND	ND	ND	ND	G12C	G12C	Yes	SD
24	wt	wt	ND	ND	ND	ND	wt	wt	No	—
25	wt	wt	ND	ND	ND	ND	G12C	wt	No	—