Table of contents

Volume 99, Issue 3
Published online 29 July 2008 (385-556)

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Editorial

Promises and caveats of in silico biomarker discovery FREE

L Pusztai and B Leyland-Jones

Br J Cancer 99: 385-386; doi:10.1038/sj.bjc.6604495

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Minireviews

Resistance to chemotherapy: new treatments and novel insights into an old problem FREE

S Raguz and E Yagüe

Br J Cancer 99: 387-391; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604510

Tumour-targeted nanomedicines: principles and practice FREE

T Lammers, W E Hennink and G Storm

Br J Cancer 99: 392-397; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604483

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Clinical Studies

PRAME expression and clinical outcome of breast cancer FREE

M T Epping, A A M Hart, A M Glas, O Krijgsman and R Bernards

Br J Cancer 99: 398-403; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604494

High-risk human papillomavirus infections in breast cancer in Syrian women and their association with Id-1 expression: a tissue microarray study FREE

N Akil, A Yasmeen, A Kassab, L Ghabreau, A D Darnel and A-E Al Moustafa

Br J Cancer 99: 404-407; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604503

Human papillomavirus detected in female breast carcinomas in Japan FREE

N A Khan, A Castillo, C Koriyama, Y Kijima, Y Umekita, Y Ohi, M Higashi, Y Sagara, H Yoshinaka, T Tsuji, S Natsugoe, T Douchi, Y Eizuru and S Akiba

Br J Cancer 99: 408-414; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604502

Implementing a system of quality-of-life diagnosis and therapy for breast cancer patients: results of an exploratory trial as a prerequisite for a subsequent RCT FREE

M Klinkhammer-Schalke, M Koller, C Ehret, B Steinger, B Ernst, J C Wyatt, F Hofstädter and W Lorenz for the Regensburg QoL Study Group

Br J Cancer 99: 415-422; doi:10.1038/sj.bjc.6604505

Effectiveness of service screening: a case–control study to assess breast cancer mortality reduction FREE

D Puliti, G Miccinesi, N Collina, V De Lisi, M Federico, S Ferretti, A C Finarelli, F Foca, L Mangone, C Naldoni, M Petrella, A Ponti, N Segnan, A Sigona, M Zarcone, M Zorzi, M Zappa and E Paci the IMPACT Working Group

Br J Cancer 99: 423-427; doi:10.1038/sj.bjc.6604532

Target and reality of adjuvant endocrine therapy in postmenopausal patients with invasive breast cancer FREE

U Güth, D J Huang, A Schötzau, R Zanetti-Dällenbach, W Holzgreve, J Bitzer and E Wight

Br J Cancer 99: 428-433; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604525

Dietary glycaemic index, glycaemic load and endometrial and ovarian cancer risk: a systematic review and meta-analysis FREE

H G Mulholland, L J Murray, C R Cardwell and M M Cantwell

Br J Cancer 99: 434-441; doi:10.1038/sj.bjc.6604496

Phase III randomised trial of doxorubicin-based chemotherapy compared with platinum-based chemotherapy in small-cell lung cancer FREE

S Baka, R Califano, R Ferraldeschi, L Aschroft, N Thatcher, P Taylor, C Faivre-Finn, F Blackhall and P Lorigan

Br J Cancer 99: 442-447; doi:10.1038/sj.bjc.6604480

The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation FREE

P Wolter, C Stefan, B Decallonne, H Dumez, M Bex, P Carmeliet and P Schöffski

Br J Cancer 99: 448-454; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604497

Biweekly cetuximab and irinotecan in advanced colorectal cancer patients progressing after at least one previous line of chemotherapy: results of a phase II single institution trial FREE

P Martín-Martorell, S Roselló, E Rodríguez-Braun, I Chirivella, A Bosch and A Cervantes

Br J Cancer 99: 455-458; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604530

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Translational Therapeutics

Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein Bid in ex vivo colorectal cancer FREE

M M Seenath, D Roberts, C Cawthorne, M P Saunders, G R Armstrong, S T O'Dwyer, I J Stratford, C Dive and A G Renehan

Br J Cancer 99: 459-463; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604474

The xc - cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance FREE

M Lo, V Ling, Y Z Wang and P W Gout

Br J Cancer 99: 464-472; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604485

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs FREE

T Gelardi, R Caputo, V Damiano, G Daniele, S Pepe, F Ciardiello, M Lahn, R Bianco and G Tortora

Br J Cancer 99: 473-480; doi:10.1038/sj.bjc.6604493

[18F]FDG and [18F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study FREE

W G E Direcks, S C Berndsen, N Proost, G J Peters, J Balzarini, M D Spreeuwenberg, A A Lammertsma and C F M Molthoff

Br J Cancer 99: 481-487; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604523

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Molecular Diagnostics

The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias FREE

I S Mahmoud, M A Sughayer, H A Mohammad, A A Eshtayeh, A S Awidi, M S EL-Khateeb and S I Ismail

Br J Cancer 99: 488-490; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604512

Identification of claudin-4 as a marker highly overexpressed in both primary and metastatic prostate cancer FREE

K A Landers, H Samaratunga, L Teng, M Buck, M J Burger, B Scells, M F Lavin and R A Gardiner

Br J Cancer 99: 491-501; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604486

Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells FREE

G O'Callaghan, J Kelly, F Shanahan and A Houston

Br J Cancer 99: 502-512; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604490

Genomic instability and proliferative activity as risk factors for distant metastases in breast cancer FREE

L Li, K Mu, G Zhou, L Lan, G Auer and A Zetterberg

Br J Cancer 99: 513-519; doi:10.1038/sj.bjc.6604479

MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells FREE

M P Ponnusamy, A P Singh, M Jain, S Chakraborty, N Moniaux and S K Batra

Br J Cancer 99: 520-526; doi:10.1038/sj.bjc.6604517

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Epidemiology

Obesity and risk of pancreatic cancer among postmenopausal women: the Women's Health Initiative (United States) FREE

J Luo, K L Margolis, H-O Adami, A LaCroix and W Ye For the Women's Health Initiative Investigators

Br J Cancer 99: 527-531; advance online publication, July 15, 2008; doi:10.1038/sj.bjc.6604487

Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology FREE

H Brenner, M Hoffmeister and U Haug

Br J Cancer 99: 532-535; advance online publication, July 15, 2008; doi:10.1038/sj.bjc.6604488

Modification of second cancer risk after malignant melanoma by parental history of cancer FREE

H Zhang, J Lorenzo Bermejo, J Sundquist and K Hemminki

Br J Cancer 99: 536-538; advance online publication, July 15, 2008; doi:10.1038/sj.bjc.6604489

Second breast cancers in a Tuscan case series: characteristics, prognosis, and predictors of survival FREE

S Ciatto, N Houssami, F Martinelli, R Bonardi, F H Cafferty and S W Duffy

Br J Cancer 99: 539-544; advance online publication, July 15, 2008; doi:10.1038/sj.bjc.6604481

Childhood cancer in the offspring born in 1921–1984 to US radiologic technologists FREE

K J Johnson, B H Alexander, M M Doody, A J Sigurdson, M S Linet, L G Spector, R W Hoffbeck, S L Simon, R M Weinstock and J A Ross

Br J Cancer 99: 545-550; advance online publication, July 29, 2008; doi:10.1038/sj.bjc.6604516

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Letters to the Editor

Clinical interest of KRAS mutation detection in blood for anti-EGFR therapies in metastatic colorectal cancer FREE

F Di Fiore, F Charbonnier, B Lefebure, M Laurent, F Le Pessot, P Michel and T Frebourg

Br J Cancer 99: 551-552; advance online publication, July 1, 2008; doi:10.1038/sj.bjc.6604451

Is serum matrix metalloproteinase 9 a useful biomarker in detection of colorectal cancer? Considering pre-analytical interference that may influence diagnostic accuracy FREE

K Jung

Br J Cancer 99: 553-554; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604491

Reply: Is serum matrix metalloproteinase 9 a useful biomarker in detection of colorectal cancer? Considering pre-analytical interference that may influence diagnostic accuracy FREE

N G Hurst

Br J Cancer 99: 555; advance online publication, July 22, 2008; doi:10.1038/sj.bjc.6604492

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Corrigendum

Reply: Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients FREE

N G Hurst, D D Stocken, S Wilson, C Keh, M J O Wakelam and T Ismail

Br J Cancer 99: 556; doi:10.1038/sj.bjc.6604543

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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