1. ¹Division of Epidemiology/Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, SE MMC 715, Minneapolis, MN 55455, USA
2. ²Cancer Center, University of Minnesota, 420 Delaware Street, SE MMC 715, Minneapolis, MN 55455, USA
3. ³Minnesota Department of Health, PO Box 64975, St Paul, MN 55164-0975, USA

Correspondence: Dr LG Spector, Assistant Professor, Division of Epidemiology/Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, SE MMC 715, Minneapolis, MN 55455, USA. E-mail: spector@umn.edu

Received 18 January 2008; Revised 27 February 2008; Accepted 7 March 2008; Published online 8 April 2008.

Abstract

We confirmed the strong association of hepatoblastoma with very low birth weight (relative risk <1000 g vs 2000 g=25.6; 95% confidence interval: 7.70–85.0) and demonstrated independent associations with congenital abnormalities and maternal Asian race in a population-based Minnesota study that included 36 cases and 7788 controls.