FIGURE 2
FROM:
Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma
M R Morris, D Gentle, M Abdulrahman, N Clarke, M Brown, T Kishida, M Yao, B T Teh, F Latif and E R Maher
BACK TO ARTICLEFigure 2.
Re-expression of CXCL16 in RCC cells results in growth suppression. Equal (molar) amounts of empty vector (EV) and pCDNA3.1-CXCL16 (CXCL16) were transfected into SKRC39 cells. Following antibiotic selection, surviving colonies were stained. Each experiment was performed in triplicate and the means of these used to produce the bar chart. The mean number of colonies counted in the EV plates was taken as 100%. There was a statistically significant reduction of colonies in each of the CXCL16 transfectants (P=0.0141).
