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British Journal of Cancer (2007) 97, 949-951.
doi:10.1038/sj.bjc.6603981 www.bjcancer.com Published online 18 September 2007
Chlamydiae and Mycoplasma infections in pulmonary MALT lymphoma
E Chanudet1, P Adam2, A G Nicholson3, A C Wotherspoon4, R Ranaldi5, G Goteri5, S A Pileri6, H Ye1, H K Müller-Hermelink2 and M-Q Du1
1Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Box 231, Level 3, Lab Block Addenbrooke's Hospital, Hills road, Cambridge CB2 0QQ, UK
2Institute of Pathology, University of Würzburg, Würzburg 97080, Germany
3Department of Histopathology, Royal Brompton Hospital, London SW3 6PN, UK
4Department of Histopathology, Royal Marsden Hospital, London SW3 6JJ, UK
5Anatomia Patologica, Università Politecnica delle Marche, Torrette di Ancona 60020, Italy
6Unità Operativa di Emolinfopatologia - Università degli Studi di Bologna, Bologna 40138, Italy
Correspondence to: Professor M-Q Du, E-mail: mqd20@cam.ac.uk
Received 2 May 2007; revised 15 August 2007; accepted 15 August 2007; published online 18 September 2007
Chlamydia pneumoniae, Chlamydia trachomatis and Chlamydia psittaci were detected at low frequencies (<20%) among 69 pulmonary mucosa-associated lymphoid tissue (MALT) lymphomas, 30 other lymphoproliferative disorders (LPD) and 44 non-LPD. The incidence of individual Chlamydiae was generally higher in MALT lymphoma than non-LPD, although not reaching statistical significance. Mycoplasma pneumoniae DNA was not detected.
Keywords: pulmonary MALT lymphoma; Chlamydia; Mycoplasma
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