British Journal of Cancer

TABLE 2

FROM:

Recent increase of breast cancer incidence among women under the age of forty

C Bouchardy, G Fioretta, H M Verkooijen, G Vlastos, P Schaefer, J-F Delaloye, I Neyroud-Caspar, S Balmer Majno, Y Wespi, M Forni, P Chappuis, A-P Sappino and E Rapiti

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Table 2. Comparison of tumour assessment and characteristics of breast cancer patients aged <40 years before and after the increase began

  1995–2001 2002–2004  
Patient and tumour characteristics Number (%) Number (%) P-value for heterogeneity test
Age at diagnosis
 25–29 years6(7)6(10)0.523
 30–34 years32(35)17(27) 
 35–39 years54(59)40(64) 
Method of detection
 Screening8(9)12(19)0.168
 Breast self-examination66(72)40(64) 
 Symptoms, other18(20)11(18) 
Diagnostic assessment
 Clinical statusa 81(88)58(92)0.419
 Mammography or ultrasounda 80(87)56(88)0.719
 MRIa 24(26)30(48)0.006
Family history
 Negative64(70)41(65)0.557
 Positive28(30)22(35) 
Stage
 I37(40)21(33)0.673
 II41(45)27(43) 
 III7(8)9(14) 
 IV4(4)3(5) 
 Unknown3(3)3(5) 
Histology
 Ductal81(88)60(95)0.078
 Lobular0(0)1(2) 
 Other11(12)2(3) 
Grade
 I15(16)8(13)0.217
 II33(36)33(52) 
 III38(41)20(32) 
 Unknown6(7)2(3) 
Oestrogen receptor status
 Negative33(36)18(29)0.630
 Positive56(61)43(68) 
 Unknown3(3)2(3) 
Progesterone receptor status
 Negative37(40)25(40)0.997
 Positive52(57)36(57) 
 Unknown3(3)2(3) 
Total92(100)63(100) 

 MRI=magnetic resonance imaging.

a Binary variables classified as yes vs no.

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