Table of contents

Volume 95, Issue 8
Published online 17 October 2006 (953-1129)

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Editorial

A perspective on euthanasia FREE

D Oliver

Br J Cancer 95: 953-954; doi:10.1038/sj.bjc.6603365

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Minireviews

Predicted mechanisms of resistance to mTOR inhibitors FREE

R T Kurmasheva, S Huang and P J Houghton

Br J Cancer 95: 955-960; advance online publication, September 5, 2006; doi:10.1038/sj.bjc.6603353

A novel proteasome inhibitor NPI-0052 as an anticancer therapy FREE

D Chauhan, T Hideshima and K C Anderson

Br J Cancer 95: 961-965; doi:10.1038/sj.bjc.6603406

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Clinical Studies

Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer FREE

C von Plessen, B Bergman, O Andresen, R M Bremnes, S Sundstrøm, M Gilleryd, R Stephens, J Vilsvik, U Aasebø and S Sörenson for the Norwegian Lung Cancer Study Group

Br J Cancer 95: 966-973; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603383

Familial breast cancer: management of 'lower risk' referrals FREE

D Young, L McLeish, F Sullivan, M Pitkethly, M Reis, D Goudie, H Vysny, G Ozakinci and M Steel

Br J Cancer 95: 974-978; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603389

The impact of the Calman–Hine report on the processes and outcomes of care for Yorkshire's colorectal cancer patients FREE

E Morris, R A Haward, M S Gilthorpe, C Craigs and D Forman

Br J Cancer 95: 979-985; doi:10.1038/sj.bjc.6603372

Increased risk of malignancies in a population-based study of 818 soft-tissue sarcoma patients FREE

J Fernebro, A Bladström, A Rydholm, P Gustafson, H Olsson, J Engellau and M Nilbert

Br J Cancer 95: 986-990; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603401

Secondary dissemination in children with high-grade malignant gliomas and diffuse intrinsic pontine gliomas FREE

S Wagner, M Benesch, F Berthold, A K Gnekow, S Rutkowski, R Sträter, M Warmuth-Metz, R-D Kortmann, T Pietsch and J E A Wolff

Br J Cancer 95: 991-997; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603402

A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations FREE

H Asahina, K Yamazaki, I Kinoshita, N Sukoh, M Harada, H Yokouchi, T Ishida, S Ogura, T Kojima, Y Okamoto, Y Fujita, H Dosaka–Akita, H Isobe and M Nishimura on behalf of the Hokkaido Lung Cancer Clinical Study Group

Br J Cancer 95: 998-1004; doi:10.1038/sj.bjc.6603393

Weekly cisplatin, epirubicin, and paclitaxel with granulocyte colony-stimulating factor support vs triweekly epirubicin and paclitaxel in locally advanced breast cancer: final analysis of a sicog phase III study FREE

G Frasci, G D'Aiuto, P Comella, R Thomas, G Botti, M Di Bonito, V De Rosa, G Iodice, M R Rubulotta and G Comella for the Southern Italy Cooperative Oncology Group (SICOG)- Italy

Br J Cancer 95: 1005-1012; doi:10.1038/sj.bjc.6603395

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Translational Therapeutics

Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation FREE

G Vlahovic, Z N Rabbani, J E Herndon II, M W Dewhirst and Z Vujaskovic

Br J Cancer 95: 1013-1019; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603366

The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro  FREE

T Alain, M Kim, R N Johnston, S Urbanski, A E Kossakowska, P A Forsyth and P W K Lee

Br J Cancer 95: 1020-1027; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603363

Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice FREE

C Bing, S Russell, E Becket, M Pope, M J Tisdale, P Trayhurn and J R Jenkins

Br J Cancer 95: 1028-1037; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603360

Moxifloxacin enhances antiproliferative and apoptotic effects of etoposide but inhibits its proinflammatory effects in THP-1 and Jurkat cells FREE

I Fabian, D Reuveni, A Levitov, D Halperin, E Priel and I Shalit

Br J Cancer 95: 1038-1046; doi:10.1038/sj.bjc.6603355

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Molecular Diagnostics

Case–control, kin-cohort and meta-analyses provide no support for STK15 F31I as a low penetrance colorectal cancer allele FREE

E L Webb, M F Rudd and R S Houlston

Br J Cancer 95: 1047-1049; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603382

Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma FREE

K T Ng, K Man, C K Sun, T K Lee, R T Poon, C-M Lo and S-T Fan

Br J Cancer 95: 1050-1055; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603399

Altered sirtuin expression is associated with node-positive breast cancer FREE

N Ashraf, S Zino, A MacIntyre, D Kingsmore, A P Payne, W D George and P G Shiels

Br J Cancer 95: 1056-1061; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603384

Prognostic value of increase in transcript levels of Tp73 DeltaEx2-3 isoforms in low-grade glioma patients FREE

M Wager, J Guilhot, J-L Blanc, S Ferrand, S Milin, B Bataille, F Lapierre, S Denis, T Chantereau, C-J Larsen and L Karayan-Tapon

Br J Cancer 95: 1062-1069; doi:10.1038/sj.bjc.6603410

Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer FREE

F Oshita, S Matsukuma, M Yoshihara, Y Sakuma, N Ohgane, Y Kameda, H Saito, K Yamada, E Tsuchiya and Y Miyagi

Br J Cancer 95: 1070-1075; doi:10.1038/sj.bjc.6603396

The longitudinal relationship between circulating concentrations of C-reactive protein, interleukin-6 and interleukin-10 in patients undergoing resection for renal cancer FREE

S Ramsey, G W A Lamb, M Aitchison and D C McMillan

Br J Cancer 95: 1076-1080; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603387

Prognostic relevance of Tiam1 protein expression in prostate carcinomas FREE

R Engers, M Mueller, A Walter, J G Collard, R Willers and H E Gabbert

Br J Cancer 95: 1081-1086; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603385

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Genetics and Genomics

Association of decreased mitochondrial DNA content with ovarian cancer progression FREE

Y Wang, V W S Liu, W C Xue, A N Y Cheung and H Y S Ngan

Br J Cancer 95: 1087-1091; advance online publication, October 3, 2006; doi:10.1038/sj.bjc.6603377

Gene expression profiling of human ovarian tumours FREE

S Biade, M Marinucci, J Schick, D Roberts, G Workman, E H Sage, P J O'Dwyer, V A LiVolsi and S W Johnson

Br J Cancer 95: 1092-1100; advance online publication, September 12, 2006; doi:10.1038/sj.bjc.6603346

Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer FREE

E Miranda, A Destro, A Malesci, E Balladore, P Bianchi, E Baryshnikova, G Franchi, E Morenghi, L Laghi, L Gennari and M Roncalli

Br J Cancer 95: 1101-1107; advance online publication, September 12, 2006; doi:10.1038/sj.bjc.6603337

Reduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemia FREE

A Scardocci, F Guidi, F D'Alo', D Gumiero, E Fabiani, A DiRuscio, M Martini, L M Larocca, M Zollino, S Hohaus, G Leone and M T Voso

Br J Cancer 95: 1108-1113; doi:10.1038/sj.bjc.6603392

TIMP-1 gene deficiency increases tumour cell sensitivity to chemotherapy-induced apoptosis FREE

M L Davidsen, SØ Würtz, M U Rømer, N M Sørensen, S K Johansen, I J Christensen, J K Larsen, H Offenberg, N Brünner and U Lademann

Br J Cancer 95: 1114-1120; doi:10.1038/sj.bjc.6603378

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Letters to the Editor

Enhancing the quality of clinical trials in cancer pain first requires that pain assessment methods are appropriately understood and used FREE

A Caraceni, C Brunelli, C Martini, E Zecca and F De Conno

Br J Cancer 95: 1121; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603357

A model of the natural history of screen-detected prostate cancer FREE

C Metcalfe, J A Lane, F Hamdy, D Neal and J L Donovan on behalf of the ProtecT Study Research Group

Br J Cancer 95: 1122-1123; advance online publication, September 26, 2006; doi:10.1038/sj.bjc.6603368

Familial ovarian screening – effective or ineffective? FREE

I J Jacobs, J Mackay, U Menon, S J Skates, A N Rosenthal and L Fraser

Br J Cancer 95: 1124; doi:10.1038/sj.bjc.6603407

High percentage of abnormal findings on TVU needs further discussion FREE

M J E Mourits, N M van der Velde, H J G Arts and G H de Bock

Br J Cancer 95: 1125; doi:10.1038/sj.bjc.6603408

Reply: Familial ovarian screening: how to address abnormal TVU findings and its influence on the efficacy of screening? FREE

A L M Oei, L F A G Massuger, J Bulten, M J L Ligtenberg, N Hoogerbrugge and J A de Hullu

Br J Cancer 95: 1126-1127; doi:10.1038/sj.bjc.6603409

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Book Reviews

The Molecular Biology of Cancer FREE

V Emuss

Br J Cancer 95: 1128; doi:10.1038/sj.bjc.6603379

Death and Medical Power: An Ethical Analysis of Dutch Euthanasia Practice FREE

D Oliver

Br J Cancer 95: 1129; doi:10.1038/sj.bjc.6603373

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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