Epidemiology
British Journal of Cancer (2006) 95, 363–365. doi:10.1038/sj.bjc.6603250 www.bjcancer.com
Published online 25 July 2006
Use of nonsteroidal anti-inflammatory drugs and risk of oral cancer: a cohort study
S Friis1, A Poulsen1, L Pedersen2, J A Baron3 and H T Sørensen2
- 1Institute of Cancer Epidemiology, Department of Genetics and Medicine, Danish Cancer Society, DK-2100 Copenhagen, Denmark
- 2Department of Clinical Epidemiology, Aarhus University Hospital, Ole Worms Allé 1150, DK-8000 Aarhus C, Denmark
- 3Departments of Medicine and Community and Family Medicine, Dartmouth Medical School, Dartmouth College, Hanover 03755-3861, NH, USA
Correspondence: Dr S Friis, E-mail: friis@cancer.dk
Received 2 May 2006; Revised 9 June 2006; Accepted 9 June 2006; Published online 25 July 2006.
Abstract
Epidemiologic data regarding the chemopreventive potential of nonsteroidal anti-inflammatory drugs (NSAIDs) against oral cancer are sparse. We found a relative risk for oral cancer of 1.2 (95% CI, 1.0–1.6) among 169 589 Danish NSAID users (
2 prescriptions), with no apparent trends in subgroups. Our study provided no clear evidence that NSAIDs may protect against oral cancer.
Keywords:
nonsteroidal anti-inflammatory drugs, oral cancer, population based, risk, cohort study
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