Table of contents

Volume 94, Issue 2
Published online 24 January 2006 (179-340)

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Minireviews

Epigenetics provides a new generation of oncogenes and tumour-suppressor genes FREE

M Esteller

Br J Cancer 94: 179-183; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602918

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival FREE

H-W Lo and M-C Hung

Br J Cancer 94: 184-188; doi:10.1038/sj.bjc.6602941

Primary thromboprophylaxis for cancer patients with central venous catheters – a reappraisal of the evidence FREE

M S Cunningham, B White, D Hollywood and J O'Donnell

Br J Cancer 94: 189-194; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602917

mTOR signaling: implications for cancer and anticancer therapy FREE

E Petroulakis, Y Mamane, O Le Bacquer, D Shahbazian and N Sonenberg

Br J Cancer 94: 195-199; advance online publication, December 13, 2005; doi:10.1038/sj.bjc.6602902

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Clinical Studies

Increased risk of venous thromboembolism in patients with acute leukaemia FREE

M Mohren, I Markmann, K Jentsch-Ullrich, M Koenigsmann, G Lutze and A Franke

Br J Cancer 94: 200-202; advance online publication, January 17, 2006; doi:10.1038/sj.bjc.6602945

The prognostic significance of genetic polymorphisms (Methylenetetrahydrofolate Reductase C677T, Methionine Synthase A2756G, Thymidilate Synthase tandem repeat polymorphism) in multimodally treated oesophageal squamous cell carcinoma FREE

M Sarbia, M Stahl, C von Weyhern, G Weirich and F Pühringer-Oppermann

Br J Cancer 94: 203-207; advance online publication, December 6, 2005; doi:10.1038/sj.bjc.6602900

Disarming the guarded prognosis: predicting survival in newly referred patients with incurable cancer FREE

M R Stockler, M H N Tattersall, M J Boyer, S J Clarke, P J Beale and R J Simes

Br J Cancer 94: 208-212; advance online publication, December 13, 2005; doi:10.1038/sj.bjc.6602908

Refining the role of laparoscopy and laparoscopic ultrasound in the staging of presumed pancreatic head and ampullary tumours FREE

B N J Thomson, R W Parks, D N Redhead, F K S Welsh, K K Madhavan, S J Wigmore and O J Garden

Br J Cancer 94: 213-217; doi:10.1038/sj.bjc.6602919

Monocytes and neutrophils as 'bad guys' for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma – results from a randomised phase II trial FREE

F Donskov, M Hokland, N Marcussen, H H Torp Madsen and H von der Maase

Br J Cancer 94: 218-226; doi:10.1038/sj.bjc.6602937

Evaluation of an inflammation-based prognostic score (GPS) in patients with metastatic breast cancer FREE

A M Al Murri, J M S Bartlett, P A Canney, J C Doughty, C Wilson and D C McMillan

Br J Cancer 94: 227-230; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602922

Impact of familial risk factors on management and survival of early-onset breast cancer: a population-based study FREE

H M Verkooijen, P O Chappuis, E Rapiti, G Vlastos, G Fioretta, S Sarp, A P Sappino, H Schubert and C Bouchardy

Br J Cancer 94: 231-238; advance online publication, December 13, 2005; doi:10.1038/sj.bjc.6602914

Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival FREE

S Desruisseau, J Palmari, C Giusti, S Romain, P-M Martin and Y Berthois

Br J Cancer 94: 239-246; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602920

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Translational Therapeutics

PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer FREE

T Fujita, H Doihara, K Kawasaki, D Takabatake, H Takahashi, K Washio, K Tsukuda, Y Ogasawara and N Shimizu

Br J Cancer 94: 247-252; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602926

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Molecular Diagnostics

Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence FREE

N Barnes, P Haywood, P Flint, W F Knox and N J Bundred

Br J Cancer 94: 253-258; advance online publication, January 17, 2006; doi:10.1038/sj.bjc.6602932

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? FREE

L Arnould, M Gelly, F Penault-Llorca, L Benoit, F Bonnetain, C Migeon, V Cabaret, V Fermeaux, P Bertheau, J Garnier, J-F Jeannin and B Coudert

Br J Cancer 94: 259-267; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602930

Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism FREE

D Meierhofer, J A Mayr, K Fink, N Schmeller, B Kofler and W Sperl

Br J Cancer 94: 268-274; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602929

Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma FREE

K Hiraoka, M Miyamoto, Y Cho, M Suzuoki, T Oshikiri, Y Nakakubo, T Itoh, T Ohbuchi, S Kondo and H Katoh

Br J Cancer 94: 275-280; advance online publication, January 17, 2006; doi:10.1038/sj.bjc.6602934

Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS) – novel predictors for response and survival in gastric cancer patients FREE

E Goekkurt, S Hoehn, C Wolschke, C Wittmer, C Stueber, D K Hossfeld and J Stoehlmacher

Br J Cancer 94: 281-286; advance online publication, November 29, 2005; doi:10.1038/sj.bjc.6602891

Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis FREE

D G Ward, Y Cheng, G N'kontchou, T T Thar, N Barget, W Wei, L J Billingham, A Martin, M Beaugrand and P J Johnson

Br J Cancer 94: 287-292; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602923

Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2 FREE

S Kazama, T Watanabe, Y Ajioka, T Kanazawa and H Nagawa

Br J Cancer 94: 293-298; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602927

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Genetics and Genomics

Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study FREE

F Canzian, J D McKay, R J Cleveland, L Dossus, C Biessy, S Rinaldi, S Landi, C Boillot, S Monnier, V Chajès, F Clavel-Chapelon, B Téhard, J Chang-Claude, J Linseisen, P H Lahmann, T Pischon, D Trichopoulos, A Trichopoulou, D Zilis, D Palli, R Tumino, P Vineis, F Berrino, H B Bueno-de-Mesquita, C H van Gils, P H M Peeters, G Pera, E Ardanaz, M-D Chirlaque, J R Quirós, N Larrañaga, C Martínez-García, N E Allen, T J Key, S A Bingham, K-T Khaw, N Slimani, T Norat, E Riboli and R Kaaks

Br J Cancer 94: 299-307; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602936

Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers FREE

Z Kote-Jarai, A Salmon, T Mengitsu, M Copeland, A Ardern-Jones, I Locke, S Shanley, B Summersgill, Y-J Lu, J Shipley and R Eeles

Br J Cancer 94: 308-310; advance online publication, December 13, 2005; doi:10.1038/sj.bjc.6602912

BRAF mutations and phosphorylation status of mitogen-activated protein kinases in the development of flat and depressed-type colorectal neoplasias FREE

K Konishi, M Takimoto, K Kaneko, R Makino, Y Hirayama, H Nozawa, T Kurahashi, Y Kumekawa, T Yamamoto, H Ito, N Yoshikawa, M Kusano, K Nakayama, B J Rembacken, H Ota and M Imawari

Br J Cancer 94: 311-317; advance online publication, December 13, 2005; doi:10.1038/sj.bjc.6602911

COSMIC 2005 FREE

S Forbes, J Clements, E Dawson, S Bamford, T Webb, A Dogan, A Flanagan, J Teague, R Wooster, P A Futreal and M R Stratton

Br J Cancer 94: 318-322; advance online publication, January 17, 2006; doi:10.1038/sj.bjc.6602928

Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome FREE

S E Bojesen, O Ammerpohl, A Weinhäusl, O A Haas, H Mettal, R M Bohle, A Borkhardt and U Fuchs

Br J Cancer 94: 323-332; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602939

A multiplex PCR predictor for aCGH success of FFPE samples FREE

E H van Beers, S A Joosse, M J Ligtenberg, R Fles, F B L Hogervorst, S Verhoef and P M Nederlof

Br J Cancer 94: 333-337; advance online publication, December 6, 2005; doi:10.1038/sj.bjc.6602889

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Letters to the Editor

Human papilloma virus and breast cancer FREE

K Altundag and M Z Baptista

Br J Cancer 94: 338; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602944

Reply: Human papilloma virus and breast cancer FREE

C-Y Kan, B J Iacopetta, J S Lawson and N J Whitaker

Br J Cancer 94: 339; advance online publication, January 10, 2006; doi:10.1038/sj.bjc.6602943

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Book Review

Genetic Predisposition to Cancer FREE

F Eisinger

Br J Cancer 94: 340; doi:10.1038/sj.bjc.6602883

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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