TABLE 3
FROM:
Treatment of hepatocellular carcinoma with major portal vein thrombosis by combined therapy with subcutaneous interferon-
and intra-arterial 5-fluorouracil; role of type 1 interferon receptor expression
H Ota, H Nagano, M Sakon, H Eguchi, M Kondo, T Yamamoto, M Nakamura, B Damdinsuren, H Wada, S Marubashi, A Miyamoto, K Dono, K Umeshita, S Nakamori, K Wakasa and M Monden
BACK TO ARTICLETable 3. Univariate analysis for efficiency of IFN-/5-FU combination therapy based on serum AFP, serum PIVKA-II, Child–Pugh score, CLIP score, and IFNAR2 expression
| CR/PR (n=24) | NC/PD (n=31) | P-value | |
|---|---|---|---|
| Age | |||
| <60 | 12 | 15 | >0.9999 |
 60 | 12 | 16 | |
| Gender | |||
| Male | 21 | 28 | >0.9999 |
| Female | 3 | 3 | |
| Child–Pugh | |||
| A | 8 | 11 | >0.9999 |
| B,C | 15 | 20 | |
| AFP | |||
| <400 | 14 | 15 | 0.5919 |
| 400 | 10 | 15 | |
| PIVKA-II | |||
| <65 | 3 | 1 | 0.3123 |
| 65 | 21 | 29 | |
| Okuda | |||
| 1 | 19 | 23 | 0.3270 |
| 2,3 | 3 | 8 | |
| CLIP | |||
| 0,1,2,3 | 12 | 13 | 0.7843 |
| 4,5,6 | 12 | 17 | |
| IFNAR | |||
| Negative | 0 | 4 | 0.0070 |
| Positive | 8 | 1 | |
CR=complete response; PR=partial response; NC=no change; PD=progressive disease; AFP=alpha-fetoprotein; PIVKA-II=protein induced by vitamin K antagonists or absence.
