British Journal of Cancer - Figures and tables for article: Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma

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Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma

M Sonobe, T Manabe, H Wada and F Tanaka

Figure 1.

Single-strand conformation polymorphism of the EGFR gene. Each band alteration corresponds to a specific gene mutation. (A) Exon 18. W: wild type, 1: 2156G>C, 2: 2159C>T. Allow heads: altered bands. (B) Exon 19. W: wild type. The designated types of mutation (1a–1g, 2a–2e) in exon 19 were those described in Table 3. (C) Exon 20. W: wild type, 1: 2361G>A and 2407C>A, 2: 2308ins/dup(CCAGCGTGG) with 2310C>T and 2315C>G, 3: 2311ins/dup(GCGTGGACA) with 2315C>G. Allow heads: altered bands. (D) Exon 21. W: wild type, 1: 2573T>G, 2: 2573–2573CT>AG, 3: 2573–2574TG>GT. Allow heads: altered bands.

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Table 4 - Relationship of EGFR gene mutations to clinicopathological characteristics and other genetic/epigenetic alterations in 108 patients with adenocarcinoma.

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Table 5 - Summary of previous reports on EGFR gene mutations in NSCLC.

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FIGURES AND TABLES

Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma

Figure 1.

Table 1 - Characteristics of 154 patients included in the study.

Table 2 - PCR primers and parameters.

Table 3 - Types of EGFR gene mutations found in this study.

Table 4 - Relationship of EGFR gene mutations to clinicopathological characteristics and other genetic/epigenetic alterations in 108 patients with adenocarcinoma.

Table 5 - Summary of previous reports on EGFR gene mutations in NSCLC.