TABLE 2
FROM:
In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo
K Yao, J A Gietema, S Shida, M Selvakumaran, X Fonrose, N B Haas, J Testa and P J O'Dwyer
BACK TO ARTICLETable 2. Apoptosis (%) in hypoxia-conditioned cell lines
| Cell line | HCT116 | HCP40 | HT29 | HP40 | HCT116(-/-) | HCP40(-/-) |
|---|---|---|---|---|---|---|
| Oxic | 3.2 0.3 | 4.50.2 | 4.10.3 | 2.50.1 | 3.30.2 | 3.00.3 |
| Hypoxia | 15.51.1 | 33.92.7*
| 12.80.8 | 2.10.2*
| 7.50.7 | 3.90.5*
|
HT29 and HCT116 and their hypoxia-conditioned derivatives, HP40 and HCP40, were exposed to 24 h of hypoxia as described. In addition, apoptosis was measured in a matched pair of HCT116/p53-/- cells conditioned and treated similarly.
* Denote a statistically significant difference between parental cell line and its hypoxia-conditioned derivative with P-value <0.05.
