FIGURE 1
FROM:
Engineering T cells for cancer therapy
W Mansoor, D E Gilham, F C Thistlethwaite and R E Hawkins
BACK TO ARTICLEFigure 1.
Generation of tumour antigen-specific T cells. Different strategies have been employed to endow T cells with the specificity and power to specifically kill tumour. Large numbers of host T cells can be modified to become tumour reactive by transducing them to express. (A) Chimeric immune receptors or (B) tumour-specific T-cell receptors using retroviral technology. (C) Tumour reactive T cells are identified and grown out of a population of tumour infiltrating lymphocytes. These cells are then expanded for use.
