Epidemiology

British Journal of Cancer (2005) 92, 1326–1328. doi:10.1038/sj.bjc.6602475 www.bjcancer.com
Published online 15 March 2005

Tobacco smoking, snuff dipping and the risk of cutaneous squamous cell carcinoma: a nationwide cohort study in Sweden

Å Odenbro1, R Bellocco1, P Boffetta1,2, B Lindelöf3 and J Adami1,4

  1. 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden
  2. 2International Agency for Research on Cancer, 69008 Lyon, France
  3. 3Department of Dermatology, Karolinska University Hospital, 171 76 Stockholm, Sweden
  4. 4Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, 171 76 Stockholm, Sweden

Correspondence: Å Odenbro, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden. E-mail: asa.odenbro@meb.ki.se

Received 23 November 2004; Revised 26 January 2005; Accepted 28 January 2005; Published online 15 March 2005.

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Abstract

We investigated whether tobacco use causes cutaneous squamous cell carcinoma (CSCC) in a large cohort study with complete and long-term follow-up. A total of 756 incident cases occurred in a cohort of 337 311 men during a 30-year follow-up period, but no association was found between any kind of smoking tobacco use and CSCC risk, nor any risk change with increasing dose, duration or time since smoking cessation. Snuff use was associated with a decreased risk of CSCC. Overall, our study provides no evidence that tobacco use increases the risk of CSCC.

Keywords:

cutaneous squamous cell carcinoma, smoking tobacco, snuff dipping, epidemiology, cohort study