Clinical Study
British Journal of Cancer (2005) 92, 625–627. doi:10.1038/sj.bjc.6602406 www.bjcancer.com
Published online 22 February 2005
The relationship between the systemic inflammatory response and survival in patients with transitional cell carcinoma of the urinary bladder
M Hilmy1, J M S Bartlett1, M A Underwood1 and D C McMillan1
1University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK
Correspondence: M Hilmy, E-mail: m.hilmy@doctors.net.uk
Received 7 June 2004; Revised 21 December 2004; Accepted 4 January 2005.
Abstract
The relationship between tumour stage, grade, elevated C-reactive protein concentration (<10/>10 mg l-1), adjuvant therapy and survival was examined in patients with biopsy proven bladder cancer (n=105). On multivariate analysis stage (HR 3.37, 95% CI 1.37–8.29, P=0.008), grade (HR 2.01, 95% CI 1.14–3.57, P=0.017) and preoperative C-reactive protein (HR 3.31, 95% CI 1.09–10.09, P=0.035) were independently associated with cancer-specific survival.
Keywords:
bladder cancer, stage, grade, C-reactive protein, survival
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