Table of contents

Volume 92, Issue 10
Published online 17 May 2005 (1817-1954)

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Editorial

Point mutation in GRIM-19: a new genetic lesion in Hurthle cell thyroid carcinomas FREE

A Fusco, G Viglietto and M Santoro

Br J Cancer 92: 1817-1818; doi:10.1038/sj.bjc.6602556

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Minireviews

Intensity-modulated radiation therapy: emerging cancer treatment technology FREE

T S Hong, M A Ritter, W A Tomé and P M Harari

Br J Cancer 92: 1819-1824; advance online publication, April 26, 2005; doi:10.1038/sj.bjc.6602577

The use of radiofrequency in cancer FREE

A R Gillams

Br J Cancer 92: 1825-1829; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602582

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Clinical Studies

Report of a Joint Cancer Research UK/Medical Research Council workshop on cancer cachexia research at the Royal College of Physicians, Tuesday, 2 December 2003 FREE

T E Steer

Br J Cancer 92: 1830-1833; advance online publication, April 19, 2005; doi:10.1038/sj.bjc.6602565

A prospective longitudinal study of performance status, an inflammation-based score (GPS) and survival in patients with inoperable non-small-cell lung cancer FREE

L M Forrest, D C McMillan, C S McArdle, W J Angerson, K Dagg and H R Scott

Br J Cancer 92: 1834-1836; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602591

Plucked human hair as a tissue in which to assess pharmacodynamic end points during drug development studies FREE

D R Camidge, K R Randall, J R Foster, C J Sadler, J A Wright, A R Soames, P J Laud, P D Smith and A M Hughes

Br J Cancer 92: 1837-1841; advance online publication, May 10, 2005; doi:10.1038/sj.bjc.6602558

Social and geographic disparities in access to reference care site for patients with colorectal cancer in France FREE

O Dejardin, A-M Bouvier, C Herbert, M Velten, A Buemi, P Delafosse, N Maarouf, S Boutreux and G Launoy

Br J Cancer 92: 1842-1845; advance online publication, May 10, 2005; doi:10.1038/sj.bjc.6602571

A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer FREE

M L Veronese, W Sun, B Giantonio, J Berlin, J Shults, L Davis, D G Haller and P J O'Dwyer

Br J Cancer 92: 1846-1849; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602569

Salvage chemotherapy with irinotecan, 5-fluorouracil and leucovorin for taxane- and cisplatin-refractory, metastatic gastric cancer FREE

S T Kim, W K Kang, J H Kang, K W Park, J Lee, S-H Lee, J O Park, K Kim, W S Kim, C W Jung, Y S Park, Y-H Im and K Park

Br J Cancer 92: 1850-1854; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602575

Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours FREE

A Awada, A Hendlisz, T Gil, S Bartholomeus, M Mano, D de Valeriola, D Strumberg, E Brendel, C G Haase, B Schwartz and M Piccart

Br J Cancer 92: 1855-1861; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602584

Survival rate in patients with hepatocellular carcinoma: a retrospective analysis of 389 patients FREE

T F Greten, F Papendorf, J S Bleck, T Kirchhoff, T Wohlberedt, S Kubicka, J Klempnauer, M Galanski and M P Manns

Br J Cancer 92: 1862-1868; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602590

Zoledronic acid significantly improves pain scores and quality of life in breast cancer patients with bone metastases: a randomised, crossover study of community vs hospital bisphosphonate administration FREE

A Wardley, N Davidson, P Barrett-Lee, A Hong, J Mansi, D Dodwell, R Murphy, T Mason and D Cameron

Br J Cancer 92: 1869-1876; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602551

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Translational Therapeutics

Gefitinib treatment affects androgen levels in non-small-cell lung cancer patients FREE

M Nishio, F Ohyanagi, A Horiike, Y Ishikawa, Y Satoh, S Okumura, K Nakagawa, K Nishio and T Horai

Br J Cancer 92: 1877-1880; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602585

Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines FREE

O Uziel, E Fenig, J Nordenberg, E Beery, H Reshef, J Sandbank, M Birenbaum, M Bakhanashvili, R Yerushalmi, D Luria and M Lahav

Br J Cancer 92: 1881-1891; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602592

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Molecular Diagnostics

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid FREE

V Máximo, T Botelho, J Capela, P Soares, J Lima, A Taveira, T Amaro, A P Barbosa, A Preto, H R Harach, D Williams and M Sobrinho-Simões

Br J Cancer 92: 1892-1898; advance online publication, April 19, 2005; doi:10.1038/sj.bjc.6602547

The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells FREE

M Mandal, S Kim, M N Younes, S A Jasser, A K El-Naggar, G B Mills and J N Myers

Br J Cancer 92: 1899-1905; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602595

Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder FREE

H-L Cheng, H-S Liu, Y-J Lin, H H-W Chen, P-Y Hsu, T-Y Chang, C-L Ho, T-S Tzai and N-H Chow

Br J Cancer 92: 1906-1914; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602593

Aberrant expression of RAB1A in human tongue cancer FREE

K Shimada, K Uzawa, M Kato, Y Endo, M Shiiba, H Bukawa, H Yokoe, N Seki and H Tanzawa

Br J Cancer 92: 1915-1921; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602594

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Genetics and Genomics

Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors FREE

F Weber, K Fukino, T Sawada, N Williams, K Sweet, R M Brena, C Plass, T Caldes, G L Mutter, M A Villalona-Calero and C Eng

Br J Cancer 92: 1922-1926; advance online publication, April 19, 2005; doi:10.1038/sj.bjc.6602557

Inflammation-associated gene expression is altered between normal human ovarian surface epithelial cells and cell lines derived from ovarian adenocarcinomas FREE

O Gubbay, W Guo, M T Rae, D Niven, S P Langdon and S G Hillier

Br J Cancer 92: 1927-1933; advance online publication, May 3, 2005; doi:10.1038/sj.bjc.6602568

Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours FREE

K Almstrup, C E Hoei-Hansen, J E Nielsen, U Wirkner, W Ansorge, N E Skakkebæk, E Rajpert-De Meyts and H Leffers

Br J Cancer 92: 1934-1941; advance online publication, April 26, 2005; doi:10.1038/sj.bjc.6602560

Quantitative relationship between functionally active telomerase and major telomerase components (hTERT and hTR) in acute leukaemia cells FREE

J H Ohyashiki, H Hisatomi, K Nagao, S Honda, T Takaku, Y Zhang, G Sashida and K Ohyashiki

Br J Cancer 92: 1942-1947; advance online publication, April 12, 2005; doi:10.1038/sj.bjc.6602546

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer FREE

A Ballestrero, A Garuti, M Bertolotto, I Rocco, D Boy, A Nencioni, L Ottonello and F Patrone

Br J Cancer 92: 1948-1952; advance online publication, April 19, 2005; doi:10.1038/sj.bjc.6602563

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Book Review

Cancer of the Skin FREE

I M Leigh

Br J Cancer 92: 1953-1954; doi:10.1038/sj.bjc.6602578

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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