FIGURE 2
FROM:
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-
B activation
S M Wyke, S T Russell and M J Tisdale
BACK TO ARTICLEFigure 2.
(A) Effect of curcumin (50 
M) on total protein degradation in the presence of PIF for 24 h, as measured by the release of [3H]phenylalanine. Myotubes were incubated with PIF alone (
) or pretreated with curcumin (
) 2 h prior to the addition of PIF. Differences from 0 nM PIF are indicated as b, P<0.01 and c, P<0.001, while differences in the presence of curcumin are indicated as d, P<0.05 and f, P<0.001. n=9. The experiment was repeated three times. (B) Chymotrypsin-like enzyme activity in soluble extracts of murine myotubes after treatment with PIF alone for 24 h (), or after treatment with PIF in the presence of curcumin (). The experiment was repeated three times (n=9). The symbols for the differences are the same as in (A).
